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Identifier: 15679688

GI number: 15679688

Start: 1550341

End: 1551498

Strand: Direct

Name: Not Available

Synonym: MTH1694

Alternate gene names: 15679688

Gene position: 1550341-1551498 (Clockwise)

Preceding gene: 15679687

Following gene: 15679691

Centisome position: 88.52

GC content: 45.51

Gene sequence:

>1158_bases
ATGATTTCTCCTAAAAAATATGCTAAAGCTGCAAAAGTGCCACCAAATGGCTTTAAAACTTCAAATGAGTTTTTTAACTA
CGTCTTTAAGGATAAAGAAATGATATGGATGGGTCAGAACACCAACCATCTTCATGATCACTCTGAAATAGCGGAAGCCA
TGATTGAATGCATAAATGAGGGCAGCTACTGCAAGTATCCACCACCTGAAGGCTTTCCTGAGCTTAAGGAACTTGTACTG
AAGGATCTGGGCCTTGGTGATGACTTTGAGGCTCTGATAACTGCAGGGGGTACTGAGTCACTCTACCTGTGCATGAACGA
TATACTTGAACCCGAGGATAATGCCATAACCTGTGACCCGGGCTACCTGATAATTGACAATTTCGCAAGCAGATTTGCAT
GCAGCGTAAAATCGGTTCCCATATACAGCAGTGAATGTGACTACAAGTTAACACCCGACCTTGTACTTGAAAACATGGAC
CGCGACACCCGTCTCATATCACTCATAGATCCCCTGAATCCGCTGGGTTCCTCGTATACAAGGGATGAGATAAAGGCATT
CGCTGACATAGCTGTGGACCATGACGTTTATCTACTCCACGATATAACCTACAGGGACTTTGCAAGGGAGCACCACCTCG
CAGCAGAATATGCACCCGAGCACACGGTTACTGTCTACAGCTTCTCCAAGATATGTGGAATGGCAGGTCTGAGGATAGGT
GCAATTGTTGCAACATCCGATATCATTGAATCAGTCAAGGGTATAGTCATAAATGATCTCGGTACAAATGTTGTCTCACA
GGCAGGTGCAATTGCAGCCCTCAAATCAAAGGCTAAATGGGTTGAAAGGATACGTAATGAGACCCTCGGTAATCAGAAGA
TCATTAAGGCTGCCGTCGATGAGGTGGAAGGAGCCTTCCTCCCGGTTTATCCATCAAATGGTAACATGATGGCCATCGAC
ATATATGAAACAGGGGTTAACCCCGTTGACCTTACAGACTACCTGCTTAAGCGGAAGATCTTCGTGAGGCAGGGCGCCTA
CACCAGCAAGATATTTGGTGATAGGTACATACGCCTCAGCTTCTCAATACCAAGAGAGCAGGTCGAGATATTCGCTGAGA
ACTTTGTGGATGTCATGGAATTCCTGAGACCATCCTGA

Upstream 100 bases:

>100_bases
TAAGAAACCCTAAAGTGGAGTTTAATTGAGGTTCAGCCTCGGGTAGGTAAGAGAAGCCTTCTTCTCTTTCGCATGGATAC
TCCTGTGCTGATGTGATAAA

Downstream 100 bases:

>100_bases
TAACCCTTTCTTTTTTCAGGCCTTTAGAATTTAATAAAGGCAGATGTCTTTGAGGTAATATGCATCCGATGATCTTCTGA
ATATTCTCTTCAACAGCTAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINEGSYCKYPPPEGFPELKELVL
KDLGLGDDFEALITAGGTESLYLCMNDILEPEDNAITCDPGYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMD
RDTRLISLIDPLNPLGSSYTRDEIKAFADIAVDHDVYLLHDITYRDFAREHHLAAEYAPEHTVTVYSFSKICGMAGLRIG
AIVATSDIIESVKGIVINDLGTNVVSQAGAIAALKSKAKWVERIRNETLGNQKIIKAAVDEVEGAFLPVYPSNGNMMAID
IYETGVNPVDLTDYLLKRKIFVRQGAYTSKIFGDRYIRLSFSIPREQVEIFAENFVDVMEFLRPS

Sequences:

>Translated_385_residues
MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINEGSYCKYPPPEGFPELKELVL
KDLGLGDDFEALITAGGTESLYLCMNDILEPEDNAITCDPGYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMD
RDTRLISLIDPLNPLGSSYTRDEIKAFADIAVDHDVYLLHDITYRDFAREHHLAAEYAPEHTVTVYSFSKICGMAGLRIG
AIVATSDIIESVKGIVINDLGTNVVSQAGAIAALKSKAKWVERIRNETLGNQKIIKAAVDEVEGAFLPVYPSNGNMMAID
IYETGVNPVDLTDYLLKRKIFVRQGAYTSKIFGDRYIRLSFSIPREQVEIFAENFVDVMEFLRPS
>Mature_385_residues
MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINEGSYCKYPPPEGFPELKELVL
KDLGLGDDFEALITAGGTESLYLCMNDILEPEDNAITCDPGYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMD
RDTRLISLIDPLNPLGSSYTRDEIKAFADIAVDHDVYLLHDITYRDFAREHHLAAEYAPEHTVTVYSFSKICGMAGLRIG
AIVATSDIIESVKGIVINDLGTNVVSQAGAIAALKSKAKWVERIRNETLGNQKIIKAAVDEVEGAFLPVYPSNGNMMAID
IYETGVNPVDLTDYLLKRKIFVRQGAYTSKIFGDRYIRLSFSIPREQVEIFAENFVDVMEFLRPS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=209, Percent_Identity=24.8803827751196, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI56713254, Length=209, Percent_Identity=24.8803827751196, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=312, Percent_Identity=22.7564102564103, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43121; Mature: 43121

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINE
CCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCC
GSYCKYPPPEGFPELKELVLKDLGLGDDFEALITAGGTESLYLCMNDILEPEDNAITCDP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCCCHHHHHHHHCCCCCCCEEEECC
GYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMDRDTRLISLIDPLNPLGSSYT
CEEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHEEEHHCCCCCCCCCCC
RDEIKAFADIAVDHDVYLLHDITYRDFAREHHLAAEYAPEHTVTVYSFSKICGMAGLRIG
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHH
AIVATSDIIESVKGIVINDLGTNVVSQAGAIAALKSKAKWVERIRNETLGNQKIIKAAVD
HHHHHHHHHHHHCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EVEGAFLPVYPSNGNMMAIDIYETGVNPVDLTDYLLKRKIFVRQGAYTSKIFGDRYIRLS
HHCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEEEE
FSIPREQVEIFAENFVDVMEFLRPS
ECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINE
CCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCC
GSYCKYPPPEGFPELKELVLKDLGLGDDFEALITAGGTESLYLCMNDILEPEDNAITCDP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCCCHHHHHHHHCCCCCCCEEEECC
GYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMDRDTRLISLIDPLNPLGSSYT
CEEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHEEEHHCCCCCCCCCCC
RDEIKAFADIAVDHDVYLLHDITYRDFAREHHLAAEYAPEHTVTVYSFSKICGMAGLRIG
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHH
AIVATSDIIESVKGIVINDLGTNVVSQAGAIAALKSKAKWVERIRNETLGNQKIIKAAVD
HHHHHHHHHHHHCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EVEGAFLPVYPSNGNMMAIDIYETGVNPVDLTDYLLKRKIFVRQGAYTSKIFGDRYIRLS
HHCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEEEE
FSIPREQVEIFAENFVDVMEFLRPS
ECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]