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Identifier: 15679217

GI number: 15679217

Start: 1109207

End: 1109704

Strand: Direct

Name: Not Available

Synonym: MTH1206

Alternate gene names: 15679217

Gene position: 1109207-1109704 (Clockwise)

Preceding gene: 15679216

Following gene: 15679218

Centisome position: 63.33

GC content: 56.43

Gene sequence:

>498_bases
ATGAAAGTGGATAGCAGCGAAGCTGTTTACGCGGGTATGAAGGATGCAGGGATAGACTTCGCCGTCAGCGTCCCCTGTGT
GAATCTCAGGACGGTCCTTGAAATGGTGGATGCCGACCCTGCCATCATGCACGTACCGGTTACCCGGGAGGAGGAGGGCT
TCGGTGTTGCAGCCGGGGCCCACATGGCTGGAAAGACAACCGCCATACTGATGCAGAACTCAGGCCTCGGTAACTCAGTG
AACGTCCTGGCCTCCCTCTACAGCCTCTACCATATCCCCATAACCATGATTGTAAGTCACCGGGGCACCGAGGGAGAGTT
CATGGAGGCCCAGGTGCCCATGGGAAGGGCCACCGGGGATATATTGAGGATCCTTGAAATACCCTTCAGGACCCCCAGAA
GTCCTGCTGAGGCCAGGGAATCCATAGGAGAACTTACAGATATCTCCCTGAGGACCAGTAAGGCCGTGGCAGTCCTGCTG
GATGTATCCTACTGGTGA

Upstream 100 bases:

>100_bases
AGAGAAGGCGTGCTGAGGGTATCGAACTGGATGAAAAGCTCCTTGAGAGGATTCTTGGAATAGCCAGAGAACTTGATATA
AATCTCGAAATTAAGGAGTT

Downstream 100 bases:

>100_bases
TATGATGCTTGAGAGAATTGAAGCCATAGAAAGGATAACGGGTGTCCTTGAGGATGAGCTCGTCATATGTAACCTTGGGT
TTCCTTCAAGGGAGCTCTAC

Product: phosphonopyruvate decarboxylase related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGAHMAGKTTAILMQNSGLGNSV
NVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGDILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLL
DVSYW

Sequences:

>Translated_165_residues
MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGAHMAGKTTAILMQNSGLGNSV
NVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGDILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLL
DVSYW
>Mature_165_residues
MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGAHMAGKTTAILMQNSGLGNSV
NVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGDILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLL
DVSYW

Specific function: Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde

COG id: COG4032

COG function: function code R; Predicted thiamine-pyrophosphate-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COMD_METTH (O27274)

Other databases:

- EMBL:   AE000666
- PIR:   A69028
- RefSeq:   NP_276334.1
- ProteinModelPortal:   O27274
- STRING:   O27274
- GeneID:   1471614
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1206
- NMPDR:   fig|187420.1.peg.1189
- eggNOG:   arNOG09105
- HOGENOM:   HBG301502
- OMA:   HRGDLKE
- ProtClustDB:   CLSK876668
- BioCyc:   MTHE187420:MTH1206-MONOMER
- BRENDA:   4.1.1.79
- InterPro:   IPR022502
- InterPro:   IPR012001
- TIGRFAMs:   TIGR03845

Pfam domain/function: PF02776 TPP_enzyme_N

EC number: =4.1.1.79

Molecular weight: Translated: 17722; Mature: 17722

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGA
CCCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEECC
HMAGKTTAILMQNSGLGNSVNVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCHHH
ILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLLDVSYW
HHHHHHCCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEEEECCC
>Mature Secondary Structure
MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGA
CCCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEECC
HMAGKTTAILMQNSGLGNSVNVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCHHH
ILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLLDVSYW
HHHHHHCCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463