Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15678913

GI number: 15678913

Start: 812250

End: 813185

Strand: Direct

Name: Not Available

Synonym: MTH893

Alternate gene names: 15678913

Gene position: 812250-813185 (Clockwise)

Preceding gene: 15678912

Following gene: 15678914

Centisome position: 46.38

GC content: 45.73

Gene sequence:

>936_bases
ATGGTAGATACCATGAATATGAAGAGGGAGTCAGAGGAAAGGCAGGGTCTTCTTGAACGTTACAATTTTCCAGAGCTCAT
TGAGGATTACCTCATTGAACTTGAGATCAGGAATTACTCTCCAAACACGATAAAGACGTACAAATCAATTGTTAAAAACT
TTTATGAGTTTCTGATGAATGAGGATGACCTCTACGATGACCGGAGGGTCCTCAGGTCCTTCAAGAGGTATATACAGTAC
CTTAAAAGGGATAAAAAGGTTACACAGAACTATATCTACCTTGTAACCGTTGTTGTTAAGAAGTTCTTTGAGTTCAGTGG
CATAGACTGCTTGGAGGAGGTTAAGGCCCCCAAGAGGACCAAGTCCCTCCCCAAGTCCCTCAATGAGGATGAGGTCAAAA
GTCTCATCAACGCCGTTGAGGTGGCTGATGATGGCTCCGTCATAAGGAGGTTCATAAAGACACGTGACCGCCTTATACTC
TCACTTCTCTACTCATCGGGTCTCAGGGTCTCTGAGCTGGTCTCACTCAGGATCAATGACATAGACCCTGATGAGAGGAC
CATAAGGATCAGGGGTAAGGGTGATAAGGATCGTATAGTCCTATTTGATGAGAACACCCGTGATCTCCTCATGGATTACC
TCAAAAGAAGGATTCATGAAAGCGAGTACCTGTTCCTCAACCGTTTCGGCGATCCCCTCACCCCCAGGTACGTTCAGATG
ATGATAAAGAACTATGCACGGAAGGCCGGGATAAAGAAGAAGGTCACCCCACACATACTGAGGCACTCCTTTGCAACCCA
CCTCCTCAAGAACGGTGTGGATATAAGGGCCATACAGCAGCTTCTGGGCCATTCAAACCTTTCAACGACACAGATATATA
CCAGTGTGGATATGCAGACCCTTAAAAATGTTTATGACAGGGCCAGACTCCTCTAA

Upstream 100 bases:

>100_bases
TGGATACAGCAGTGAGAACATAGACCGCAGCTACATGTAGTGAGAACTGCATCAGATGAGTTCGATGAGTGCATGATCCG
CAAGGTTTAAGTGGATATTT

Downstream 100 bases:

>100_bases
TTAATTTATTTTTCATTTATTTCAATAAAATTCAGGTCAGGAGCCAGAAGATTGCCTGAATTCTTCCTTCAAGGGCGGGC
TTAATTTTTCAGAAGGTCAG

Product: integrase-recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMNEDDLYDDRRVLRSFKRYIQY
LKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRTKSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLIL
SLLYSSGLRVSELVSLRINDIDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQM
MIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQTLKNVYDRARLL

Sequences:

>Translated_311_residues
MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMNEDDLYDDRRVLRSFKRYIQY
LKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRTKSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLIL
SLLYSSGLRVSELVSLRINDIDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQM
MIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQTLKNVYDRARLL
>Mature_311_residues
MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMNEDDLYDDRRVLRSFKRYIQY
LKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRTKSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLIL
SLLYSSGLRVSELVSLRINDIDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQM
MIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQTLKNVYDRARLL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=32.8767123287671, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789261, Length=315, Percent_Identity=33.968253968254, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790767, Length=189, Percent_Identity=31.7460317460317, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790768, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERCL_METTH (O26979)

Other databases:

- EMBL:   AE000666
- PIR:   D69219
- RefSeq:   NP_276030.1
- ProteinModelPortal:   O26979
- SMR:   O26979
- STRING:   O26979
- GeneID:   1471301
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH893
- NMPDR:   fig|187420.1.peg.885
- eggNOG:   arNOG04691
- HOGENOM:   HBG727654
- OMA:   TKSHEER
- PhylomeDB:   O26979
- ProtClustDB:   CLSK798030
- BioCyc:   MTHE187420:MTH893-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 36912; Mature: 36912

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: ACT_SITE 169-169 ACT_SITE 193-193 ACT_SITE 258-258 ACT_SITE 261-261 ACT_SITE 284-284 ACT_SITE 293-293

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMN
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCC
EDDLYDDRRVLRSFKRYIQYLKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHH
KSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLILSLLYSSGLRVSELVSLRIND
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
IDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQM
CCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHH
MIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LKNVYDRARLL
HHHHHHHHHCC
>Mature Secondary Structure
MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMN
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCC
EDDLYDDRRVLRSFKRYIQYLKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHH
KSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLILSLLYSSGLRVSELVSLRIND
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
IDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQM
CCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHH
MIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LKNVYDRARLL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463