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Identifier: 15678839

GI number: 15678839

Start: 742078

End: 743715

Strand: Direct

Name: Not Available

Synonym: MTH817

Alternate gene names: 15678839

Gene position: 742078-743715 (Clockwise)

Preceding gene: 15678838

Following gene: 15678840

Centisome position: 42.37

GC content: 54.46

Gene sequence:

>1638_bases
ATGAACACCGATAAACAGGGGATCAGGATCATGAAGGACGCGTCACGCCTCATAATCAATGGAATAATTTCAGGTGAAAT
AAGGACAAGGAAGGACCTTGAGAGGTTCAAGCACAGGGTCTGCCGTGAAATGGGACTTGAGAGATTCATGAGCAACTCTG
AAATCCTTGAACATGCGACTCCGGAGGAGAAAAAGGTTATAGAGGGCCTCTTGAGAAAAAAACCCACAAGGACCATCTCA
GGGGTTGCTGTCGTCGCTGTAATGTGCCAGCCCCGGGAATGCCCCCATGGGAGGTGCCTGTACTGTCCAGAGAGTGAAAA
GGCACCTCCCAGTTACACTGGAGAGGAACCTGCAGCCCTGAGGGCCAGGATGTACGATTTCCACCCCTACAGGCAGGTTT
ACAACCGCCTGGAGCAGCTCCACAGCATAGGTCACCCCGTGGATAAGGTTGAACTCATAGTTATGGGGGGGACCTTCCCC
TCCCACAGCCTCTGCTACCAGGAGTGGTTCATCTCCATGTGCCTCAAGGCCATGGTGGACTTCGGGGCGGAACTCAGGGG
CATCAGGGTGGATGTGCCAGAACACCATGGATACGTGAAGGTTGAGGACGCCCAGAGACTAAACGAGTCCTCGCCGGTGA
GATGCGTTGGCATGACCTTCGAGACAAGACCAGACTACTGCAGGGAGGAGGACGTGGACAGGATGCTGGGCCTGGGAGTT
ACCAGGGTCGAGCTGGGAGTTCAGACCATATACAACTACATCTACCAGCGGATCAAGAGAGGCCACAGCATAAGGGATGT
GGTGGAATCCAACAGGATCCTCAGGGACTCCGGGGTGAAGGTTGCCATGCACCTGATGCCTGGCCTGTTCTCAGACTTTG
AAAGGGACCTGCGCATATTCAGGAGGATATTCAGGGACCCCTCCTTCAGACCGGATATGATCAAGATATATCCCTGCCTT
GTGACCCGTGGCAGCGAACTCTACAGCCTATGGGAGAGGGGCCTCTATAAGCCCTACTCCACTGAGGAGGCGGTTGAACT
TATCGTGGAGATAAAGAAGATGATGCCGAAGTGGGTGAGGACCATGAGGATACAGAGGGATATTCCCTCACGGCTCATAG
TGGACGGTGTCAGGAAGTCCAATCTCGGTGAAATGGTCTACAGGCGCCTGGAGGAGGAGGGGGTGAGGTGCAGGTGTATA
AGGTGCCGTGAGGTTGGACACATGTCAAGGAGGGGTGTGAGGGTCGACGAGGATGCTGTTACCCTCATGGTGGAGGAGTA
CGCAGCCACCGGGGGGCGGGAGTTCTTCCTCTCCCAGGAGGACCCTGAAAATGACGTCCTTGTGGGTTTCCTGAGGCTGA
GGTTCCCATCAGAGGAGGCCCACCGCCCCGAGGTCGATGATAAAACAGCCCTTGTAAGGGAACTGCATGTATACGGTTCA
ATGCTCCCCATAGGAGAAAGGGGAGATGCCGTTGGTCAGCACAGGGGCTACGGTGAGGAGCTACTTGCAAGGGCAGAGTC
CCTGGCTGCTGATAATGGAATGGAGAAGATACTTGTAACAAGTGGGATAGGTGCCCGTGAATACTACAGCAAATTCGGAT
ACCTGAAGGAGGGCCCCTACATGGCAAAGAAACTTTAG

Upstream 100 bases:

>100_bases
ATATAGTCAGAACACTCAACCTGATGAACAAAAAAACAGAATAACCAGGATCAAAAAACTCGAGCGATGAAAAACCGAAT
GGATATGATGTACAGAATGG

Downstream 100 bases:

>100_bases
GTGGTTAAAATGAATGTGGAGACAAGGGAGGAACTTGCATCACTTATAGACCACACCAATGTGAGGGCTGATGCAACAGA
AAATGATATTGAGAGGCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNTDKQGIRIMKDASRLIINGIISGEIRTRKDLERFKHRVCREMGLERFMSNSEILEHATPEEKKVIEGLLRKKPTRTIS
GVAVVAVMCQPRECPHGRCLYCPESEKAPPSYTGEEPAALRARMYDFHPYRQVYNRLEQLHSIGHPVDKVELIVMGGTFP
SHSLCYQEWFISMCLKAMVDFGAELRGIRVDVPEHHGYVKVEDAQRLNESSPVRCVGMTFETRPDYCREEDVDRMLGLGV
TRVELGVQTIYNYIYQRIKRGHSIRDVVESNRILRDSGVKVAMHLMPGLFSDFERDLRIFRRIFRDPSFRPDMIKIYPCL
VTRGSELYSLWERGLYKPYSTEEAVELIVEIKKMMPKWVRTMRIQRDIPSRLIVDGVRKSNLGEMVYRRLEEEGVRCRCI
RCREVGHMSRRGVRVDEDAVTLMVEEYAATGGREFFLSQEDPENDVLVGFLRLRFPSEEAHRPEVDDKTALVRELHVYGS
MLPIGERGDAVGQHRGYGEELLARAESLAADNGMEKILVTSGIGAREYYSKFGYLKEGPYMAKKL

Sequences:

>Translated_545_residues
MNTDKQGIRIMKDASRLIINGIISGEIRTRKDLERFKHRVCREMGLERFMSNSEILEHATPEEKKVIEGLLRKKPTRTIS
GVAVVAVMCQPRECPHGRCLYCPESEKAPPSYTGEEPAALRARMYDFHPYRQVYNRLEQLHSIGHPVDKVELIVMGGTFP
SHSLCYQEWFISMCLKAMVDFGAELRGIRVDVPEHHGYVKVEDAQRLNESSPVRCVGMTFETRPDYCREEDVDRMLGLGV
TRVELGVQTIYNYIYQRIKRGHSIRDVVESNRILRDSGVKVAMHLMPGLFSDFERDLRIFRRIFRDPSFRPDMIKIYPCL
VTRGSELYSLWERGLYKPYSTEEAVELIVEIKKMMPKWVRTMRIQRDIPSRLIVDGVRKSNLGEMVYRRLEEEGVRCRCI
RCREVGHMSRRGVRVDEDAVTLMVEEYAATGGREFFLSQEDPENDVLVGFLRLRFPSEEAHRPEVDDKTALVRELHVYGS
MLPIGERGDAVGQHRGYGEELLARAESLAADNGMEKILVTSGIGAREYYSKFGYLKEGPYMAKKL
>Mature_545_residues
MNTDKQGIRIMKDASRLIINGIISGEIRTRKDLERFKHRVCREMGLERFMSNSEILEHATPEEKKVIEGLLRKKPTRTIS
GVAVVAVMCQPRECPHGRCLYCPESEKAPPSYTGEEPAALRARMYDFHPYRQVYNRLEQLHSIGHPVDKVELIVMGGTFP
SHSLCYQEWFISMCLKAMVDFGAELRGIRVDVPEHHGYVKVEDAQRLNESSPVRCVGMTFETRPDYCREEDVDRMLGLGV
TRVELGVQTIYNYIYQRIKRGHSIRDVVESNRILRDSGVKVAMHLMPGLFSDFERDLRIFRRIFRDPSFRPDMIKIYPCL
VTRGSELYSLWERGLYKPYSTEEAVELIVEIKKMMPKWVRTMRIQRDIPSRLIVDGVRKSNLGEMVYRRLEEEGVRCRCI
RCREVGHMSRRGVRVDEDAVTLMVEEYAATGGREFFLSQEDPENDVLVGFLRLRFPSEEAHRPEVDDKTALVRELHVYGS
MLPIGERGDAVGQHRGYGEELLARAESLAADNGMEKILVTSGIGAREYYSKFGYLKEGPYMAKKL

Specific function: Unknown

COG id: COG1243

COG function: function code KB; Histone acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23510283, Length=526, Percent_Identity=41.4448669201521, Blast_Score=400, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI133955098, Length=526, Percent_Identity=41.254752851711, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6325171, Length=552, Percent_Identity=40.036231884058, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI19920684, Length=559, Percent_Identity=40.2504472271914, Blast_Score=403, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR006638
- InterPro:   IPR005910
- InterPro:   IPR007197 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 62903; Mature: 62903

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDKQGIRIMKDASRLIINGIISGEIRTRKDLERFKHRVCREMGLERFMSNSEILEHAT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
PEEKKVIEGLLRKKPTRTISGVAVVAVMCQPRECPHGRCLYCPESEKAPPSYTGEEPAAL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
RARMYDFHPYRQVYNRLEQLHSIGHPVDKVELIVMGGTFPSHSLCYQEWFISMCLKAMVD
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FGAELRGIRVDVPEHHGYVKVEDAQRLNESSPVRCVGMTFETRPDYCREEDVDRMLGLGV
CCHHHCCEEEECCCCCCEEEECHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCH
TRVELGVQTIYNYIYQRIKRGHSIRDVVESNRILRDSGVKVAMHLMPGLFSDFERDLRIF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHH
RRIFRDPSFRPDMIKIYPCLVTRGSELYSLWERGLYKPYSTEEAVELIVEIKKMMPKWVR
HHHHCCCCCCCCCEEEEHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TMRIQRDIPSRLIVDGVRKSNLGEMVYRRLEEEGVRCRCIRCREVGHMSRRGVRVDEDAV
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCHHH
TLMVEEYAATGGREFFLSQEDPENDVLVGFLRLRFPSEEAHRPEVDDKTALVRELHVYGS
HHHHHHHHHCCCCEEEECCCCCCCCCEEEEHHEECCCCCCCCCCCCHHHHHHHHHHHHHC
MLPIGERGDAVGQHRGYGEELLARAESLAADNGMEKILVTSGIGAREYYSKFGYLKEGPY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCC
MAKKL
HHHCC
>Mature Secondary Structure
MNTDKQGIRIMKDASRLIINGIISGEIRTRKDLERFKHRVCREMGLERFMSNSEILEHAT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
PEEKKVIEGLLRKKPTRTISGVAVVAVMCQPRECPHGRCLYCPESEKAPPSYTGEEPAAL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
RARMYDFHPYRQVYNRLEQLHSIGHPVDKVELIVMGGTFPSHSLCYQEWFISMCLKAMVD
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FGAELRGIRVDVPEHHGYVKVEDAQRLNESSPVRCVGMTFETRPDYCREEDVDRMLGLGV
CCHHHCCEEEECCCCCCEEEECHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCH
TRVELGVQTIYNYIYQRIKRGHSIRDVVESNRILRDSGVKVAMHLMPGLFSDFERDLRIF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHH
RRIFRDPSFRPDMIKIYPCLVTRGSELYSLWERGLYKPYSTEEAVELIVEIKKMMPKWVR
HHHHCCCCCCCCCEEEEHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TMRIQRDIPSRLIVDGVRKSNLGEMVYRRLEEEGVRCRCIRCREVGHMSRRGVRVDEDAV
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCHHH
TLMVEEYAATGGREFFLSQEDPENDVLVGFLRLRFPSEEAHRPEVDDKTALVRELHVYGS
HHHHHHHHHCCCCEEEECCCCCCCCCEEEEHHEECCCCCCCCCCCCHHHHHHHHHHHHHC
MLPIGERGDAVGQHRGYGEELLARAESLAADNGMEKILVTSGIGAREYYSKFGYLKEGPY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCC
MAKKL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]