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Identifier: 15678779

GI number: 15678779

Start: 682504

End: 683499

Strand: Direct

Name: Not Available

Synonym: MTH754

Alternate gene names: 15678779

Gene position: 682504-683499 (Clockwise)

Preceding gene: 15678778

Following gene: 15678780

Centisome position: 38.97

GC content: 53.21

Gene sequence:

>996_bases
ATGCGCTACTTCAATGTTCTTGAGGATGGTAACTTCAGGGGCGAGGTGAGGGGTGCGAACATACTCCATGTGGATTCCCC
TGAGAGGGTGGCAGAGGAGTTCAATCTGACCCTCGATGAACTTAATGAGAGGATAGAGGAGGCAAGGAGGGTCCTTCTTG
AAAGAAGACTTGAACGTGAGGCCCCTTCTGTGGATGATAAGGTGCTCACAGACTGGAATGGCCTGATGATCGGTGCCCTT
GCACGCTGCAGCAGGGTTCTTGACCATGATGAATCCCTCAGGGCAGCTGAAGGGTGCCTTGAATTCATTGAGGGCAGGTT
AATGTCCGATGGAAGGCTACTTCACAGGTACAGGGATGGCGAGGCAGCCATAAACGGGAAACTGGATGACTACGCATTCC
TGATATGGGGTCTCCTTGAAATGTATGATGCGACCCTCCGGGAGGGGTACATCAGAAAGGCCCTTGAACTCACAGAGATC
CTCAGGGATAACTTCAGGGACTCTGATGGTGGTTTTTATCTCACAGATGATCCGGATGTTATTGTGAGGCCAAAGGAATC
AATGGATGGGGCGATTCCATCAGGTAACTCTGTTCAGATGCAGAACCTTCTGAGGCTCGGTGGTCTCCTCGAGGATGAAG
GACTGATAGATGAGGCCAGGGGGATACTGAAAGCCTTCTCCAGGAGGGTTGAATCGTCTCCAGGGGCTCACACCTTCCTC
CTGTCCTCTGCAGAGTGGGCAGTTTATGGTGGGAGGTCCCTGGTGGTTGTCTGCAGTGGAGAACCAGAAATACCTGCAGT
TCTCAGGAAAACCCTGATCCCGGATTTCACCCTCACAGTTATGGGGGGATCAGGTGACTGGTCCTTTGCCCCGGCACACC
TCAATGAGAAGGTGGCCCTGGGTGATGGGTGCACCTACTACCTCTGTGATGGCAGCAAATGCCACCCGCCAGCAGAGGAC
CCTGAAAGGGTCATCGAGTACCTGGGGGTGAAATAG

Upstream 100 bases:

>100_bases
CTCGGCCGTGGATGCTGAAAGCGGTGGTGTTGAGGGTGGTTACTACCTCTGGAGGGCATCAGAGATACAGGAGGCCCTCG
GTGATGATGCAGACCTTGTA

Downstream 100 bases:

>100_bases
ATGGGCAGACAGAAAGACCATGAGAAAGGTCCCGGTGAAATTATGGAGAGCCACGGGCACCATGAGAAGAAGGGTAAGAT
GATGGACAGCCACGGGCACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRYFNVLEDGNFRGEVRGANILHVDSPERVAEEFNLTLDELNERIEEARRVLLERRLEREAPSVDDKVLTDWNGLMIGAL
ARCSRVLDHDESLRAAEGCLEFIEGRLMSDGRLLHRYRDGEAAINGKLDDYAFLIWGLLEMYDATLREGYIRKALELTEI
LRDNFRDSDGGFYLTDDPDVIVRPKESMDGAIPSGNSVQMQNLLRLGGLLEDEGLIDEARGILKAFSRRVESSPGAHTFL
LSSAEWAVYGGRSLVVVCSGEPEIPAVLRKTLIPDFTLTVMGGSGDWSFAPAHLNEKVALGDGCTYYLCDGSKCHPPAED
PERVIEYLGVK

Sequences:

>Translated_331_residues
MRYFNVLEDGNFRGEVRGANILHVDSPERVAEEFNLTLDELNERIEEARRVLLERRLEREAPSVDDKVLTDWNGLMIGAL
ARCSRVLDHDESLRAAEGCLEFIEGRLMSDGRLLHRYRDGEAAINGKLDDYAFLIWGLLEMYDATLREGYIRKALELTEI
LRDNFRDSDGGFYLTDDPDVIVRPKESMDGAIPSGNSVQMQNLLRLGGLLEDEGLIDEARGILKAFSRRVESSPGAHTFL
LSSAEWAVYGGRSLVVVCSGEPEIPAVLRKTLIPDFTLTVMGGSGDWSFAPAHLNEKVALGDGCTYYLCDGSKCHPPAED
PERVIEYLGVK
>Mature_331_residues
MRYFNVLEDGNFRGEVRGANILHVDSPERVAEEFNLTLDELNERIEEARRVLLERRLEREAPSVDDKVLTDWNGLMIGAL
ARCSRVLDHDESLRAAEGCLEFIEGRLMSDGRLLHRYRDGEAAINGKLDDYAFLIWGLLEMYDATLREGYIRKALELTEI
LRDNFRDSDGGFYLTDDPDVIVRPKESMDGAIPSGNSVQMQNLLRLGGLLEDEGLIDEARGILKAFSRRVESSPGAHTFL
LSSAEWAVYGGRSLVVVCSGEPEIPAVLRKTLIPDFTLTVMGGSGDWSFAPAHLNEKVALGDGCTYYLCDGSKCHPPAED
PERVIEYLGVK

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=349, Percent_Identity=28.6532951289398, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25147430, Length=342, Percent_Identity=30.1169590643275, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20129985, Length=344, Percent_Identity=29.3604651162791, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: NA

Molecular weight: Translated: 36984; Mature: 36984

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFNVLEDGNFRGEVRGANILHVDSPERVAEEFNLTLDELNERIEEARRVLLERRLERE
CCCCCEECCCCCEEEECCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
APSVDDKVLTDWNGLMIGALARCSRVLDHDESLRAAEGCLEFIEGRLMSDGRLLHRYRDG
CCCCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
EAAINGKLDDYAFLIWGLLEMYDATLREGYIRKALELTEILRDNFRDSDGGFYLTDDPDV
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCE
IVRPKESMDGAIPSGNSVQMQNLLRLGGLLEDEGLIDEARGILKAFSRRVESSPGAHTFL
EECCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
LSSAEWAVYGGRSLVVVCSGEPEIPAVLRKTLIPDFTLTVMGGSGDWSFAPAHLNEKVAL
EECCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEE
GDGCTYYLCDGSKCHPPAEDPERVIEYLGVK
CCCCEEEEECCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MRYFNVLEDGNFRGEVRGANILHVDSPERVAEEFNLTLDELNERIEEARRVLLERRLERE
CCCCCEECCCCCEEEECCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
APSVDDKVLTDWNGLMIGALARCSRVLDHDESLRAAEGCLEFIEGRLMSDGRLLHRYRDG
CCCCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
EAAINGKLDDYAFLIWGLLEMYDATLREGYIRKALELTEILRDNFRDSDGGFYLTDDPDV
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCE
IVRPKESMDGAIPSGNSVQMQNLLRLGGLLEDEGLIDEARGILKAFSRRVESSPGAHTFL
EECCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
LSSAEWAVYGGRSLVVVCSGEPEIPAVLRKTLIPDFTLTVMGGSGDWSFAPAHLNEKVAL
EECCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEE
GDGCTYYLCDGSKCHPPAEDPERVIEYLGVK
CCCCEEEEECCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]