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Identifier: 15678778

GI number: 15678778

Start: 681467

End: 682504

Strand: Direct

Name: Not Available

Synonym: MTH753

Alternate gene names: 15678778

Gene position: 681467-682504 (Clockwise)

Preceding gene: 15678775

Following gene: 15678779

Centisome position: 38.91

GC content: 53.28

Gene sequence:

>1038_bases
ATGAAAGATGAGTACACCAATTCTCTCATAAAGGAGAAGAGTCCCTATTTACTGCAGCATGCACACAACCCTGTGAACTG
GTATCCATGGGGTGATGATGCCTTCAGAAAGGCCCTGGCAGAGAGGAAACCCATATTTTTATCGATAGGATACTCCACCT
GTCACTGGTGCCATGTGATGGCAAGGGAGTCCTTTGAGAACCCTGAAATCGCAGATATACTCAATCGAGACTTTGTTTCT
GTTAAGGTGGACCGGGAGGAGCGCCCGGATATTGATGCCATATACATGAGGGTCTGCCAGATGATGACAGGTGCCGGGGG
ATGGCCCCTGACGATCATCATGACACCCGAGGGTGAACCCTTCTTTGCAGGGACCTACTTCCCTCCAGAGGATAGGGGTG
GAGTCCCGGGCCTTAAGACGATCCTTGAGAGGGTTGTGATGCTCTGGAAGAAGGACGCCGACGGGATAGCTGAGACCGCG
AGGAAGGTCGTGGAGGCCCTGAAGGAAAAGCCCGCTTCATACCAGATTAAACCTGAAACCGTGGATATGGCCTACGAGTA
CCTCAGGAGGAATTTTGACAGGAAAAATGGTGGTTTCGGGTCTCAGCAGAAATTCCCAACTCCCCACAACATCCACTTCC
TCCTCACCTACCACCTCCGGAGGGGTGAGGGGGAGGCCCTTGAGATGGTCAGACTCACCCTGGAGAGGATGAGGTACGGT
GGAATATATGACCAGCTGGGTTACGGTTTCCACAGATACGCTGTTGAACCAACATGGACGATACCCCACTTTGAGAAGAT
GCTCTATGACCAGGCCCTCGCAATGACAGCCTACCTTGAGGCCTTCCAGGTGACGGGTGATGAGCTCCACCAGAGGACCG
CCCTTGAGATTTCAGAGTATGTCCTCAGGGACCTCAAGTCCCGGAGGGTGGATTCTACTCGGCCGTGGATGCTGAAAGCG
GTGGTGTTGAGGGTGGTTACTACCTCTGGAGGGCATCAGAGATACAGGAGGCCCTCGGTGATGATGCAGACCTTGTAA

Upstream 100 bases:

>100_bases
ACCGCACAGAGGAAGCAGAAGGTGACTGAAGATAATAAGGTACAGTCAACCCCTCAATTAATAAAGCGCCATCAACATAA
ATAATGGTGAGGGGGAACCA

Downstream 100 bases:

>100_bases
TGCGCTACTTCAATGTTCTTGAGGATGGTAACTTCAGGGGCGAGGTGAGGGGTGCGAACATACTCCATGTGGATTCCCCT
GAGAGGGTGGCAGAGGAGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKDEYTNSLIKEKSPYLLQHAHNPVNWYPWGDDAFRKALAERKPIFLSIGYSTCHWCHVMARESFENPEIADILNRDFVS
VKVDREERPDIDAIYMRVCQMMTGAGGWPLTIIMTPEGEPFFAGTYFPPEDRGGVPGLKTILERVVMLWKKDADGIAETA
RKVVEALKEKPASYQIKPETVDMAYEYLRRNFDRKNGGFGSQQKFPTPHNIHFLLTYHLRRGEGEALEMVRLTLERMRYG
GIYDQLGYGFHRYAVEPTWTIPHFEKMLYDQALAMTAYLEAFQVTGDELHQRTALEISEYVLRDLKSRRVDSTRPWMLKA
VVLRVVTTSGGHQRYRRPSVMMQTL

Sequences:

>Translated_345_residues
MKDEYTNSLIKEKSPYLLQHAHNPVNWYPWGDDAFRKALAERKPIFLSIGYSTCHWCHVMARESFENPEIADILNRDFVS
VKVDREERPDIDAIYMRVCQMMTGAGGWPLTIIMTPEGEPFFAGTYFPPEDRGGVPGLKTILERVVMLWKKDADGIAETA
RKVVEALKEKPASYQIKPETVDMAYEYLRRNFDRKNGGFGSQQKFPTPHNIHFLLTYHLRRGEGEALEMVRLTLERMRYG
GIYDQLGYGFHRYAVEPTWTIPHFEKMLYDQALAMTAYLEAFQVTGDELHQRTALEISEYVLRDLKSRRVDSTRPWMLKA
VVLRVVTTSGGHQRYRRPSVMMQTL
>Mature_345_residues
MKDEYTNSLIKEKSPYLLQHAHNPVNWYPWGDDAFRKALAERKPIFLSIGYSTCHWCHVMARESFENPEIADILNRDFVS
VKVDREERPDIDAIYMRVCQMMTGAGGWPLTIIMTPEGEPFFAGTYFPPEDRGGVPGLKTILERVVMLWKKDADGIAETA
RKVVEALKEKPASYQIKPETVDMAYEYLRRNFDRKNGGFGSQQKFPTPHNIHFLLTYHLRRGEGEALEMVRLTLERMRYG
GIYDQLGYGFHRYAVEPTWTIPHFEKMLYDQALAMTAYLEAFQVTGDELHQRTALEISEYVLRDLKSRRVDSTRPWMLKA
VVLRVVTTSGGHQRYRRPSVMMQTL

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=313, Percent_Identity=48.2428115015974, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI25147430, Length=291, Percent_Identity=47.0790378006873, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI20129985, Length=309, Percent_Identity=46.9255663430421, Blast_Score=305, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: NA

Molecular weight: Translated: 40084; Mature: 40084

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDEYTNSLIKEKSPYLLQHAHNPVNWYPWGDDAFRKALAERKPIFLSIGYSTCHWCHVM
CCCHHHHHHHHCCCCHHHHHCCCCCCEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
ARESFENPEIADILNRDFVSVKVDREERPDIDAIYMRVCQMMTGAGGWPLTIIMTPEGEP
HHHCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
FFAGTYFPPEDRGGVPGLKTILERVVMLWKKDADGIAETARKVVEALKEKPASYQIKPET
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCHH
VDMAYEYLRRNFDRKNGGFGSQQKFPTPHNIHFLLTYHLRRGEGEALEMVRLTLERMRYG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHC
GIYDQLGYGFHRYAVEPTWTIPHFEKMLYDQALAMTAYLEAFQVTGDELHQRTALEISEY
CCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VLRDLKSRRVDSTRPWMLKAVVLRVVTTSGGHQRYRRPSVMMQTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCC
>Mature Secondary Structure
MKDEYTNSLIKEKSPYLLQHAHNPVNWYPWGDDAFRKALAERKPIFLSIGYSTCHWCHVM
CCCHHHHHHHHCCCCHHHHHCCCCCCEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
ARESFENPEIADILNRDFVSVKVDREERPDIDAIYMRVCQMMTGAGGWPLTIIMTPEGEP
HHHCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
FFAGTYFPPEDRGGVPGLKTILERVVMLWKKDADGIAETARKVVEALKEKPASYQIKPET
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCHH
VDMAYEYLRRNFDRKNGGFGSQQKFPTPHNIHFLLTYHLRRGEGEALEMVRLTLERMRYG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHC
GIYDQLGYGFHRYAVEPTWTIPHFEKMLYDQALAMTAYLEAFQVTGDELHQRTALEISEY
CCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VLRDLKSRRVDSTRPWMLKAVVLRVVTTSGGHQRYRRPSVMMQTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]