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Identifier: 15678564

GI number: 15678564

Start: 478945

End: 480483

Strand: Direct

Name: Not Available

Synonym: MTH536

Alternate gene names: 15678564

Gene position: 478945-480483 (Clockwise)

Preceding gene: 15678563

Following gene: 15678565

Centisome position: 27.35

GC content: 57.12

Gene sequence:

>1539_bases
ATGTCCCGTGTGCGTGGAGGGGAGAACTCCACACTGATAAGGGTATCATCCACACCGGTCCGGGCCTTCATAGAAAGGGT
GGATGTGCTGTTTGCACTGAGCCCCGGTGCAGTGGAACACATGGATGGCCGTGTGAAGGATACACTGGTCATTGCAGATG
AGGAGTTCCATGAGGAGGGCGCCATCAGCCTCCCGATAATGGGGGAGGCAGAGAAGCTGGGGGGCAGGATATTCGCCAAT
GTCGTTGCAGCGGGTGCAGCCGCAAACCTCTTCGGTGTCAGAGAGGAAACATTCGATGAAGCCGTGCGGTCCCTATTCGA
ACGCAAGGGCCCTGACATAGTAGAGGCCGACCTCAGGGCCGGGAGGAAGGGCTATGAACTGGGTGATGAACTCAGGGAGC
ACCTTGAGATCAGCATTGAACCCCAGCCATCGGTGAGGGAACACGTTGTCCTCAACGGGACAGAAGCCGTTGGCATAGGG
TGCATCGCCGGGGGCTGCCGCTTCATGTCATCATACCCCATGACACCATCAACTCCACTCCAGGTATTCATATCAGAGAA
CGCCGCTGAATTCGACATGGTATTCGAGCAGGCAGAGGATGAGATTGCAGCCATCAACATGTGCCTGGGGGCCTCCTATG
CGGGTGCACGGTCCCTTGTCGCAACCTCAGGTAGCGGATTTGCCCTCATGGAGGAGGCCGTTGGCCTTGCAGGTATGATA
GAAACACCTGTGGTTATATACATAGGCCAGAGGCCGGGGCCGGCTGTTGGTCTTCCCACCAGGACAGCCCAGGAGGACCT
GAACCTCGCCCTCTACGCAGGCCCCGGTGAGTTCCCAAGGGCAATTCTGGCTCCAGGGAAACTCGAGGATGCCCCTGAAA
TCGCGGCCCATGCCTTCAACCTGGCAGACAGGTACCAGATACCTGTATTTCTGCTCTCAGACCAGTACCTGGCAGACCTC
TACTACGACCTACCCTCACCCCAGATCGGTGAGGAACCCTCTTACCATATCACCCGGACATGGGAGGGTTACAGGAGATT
CGAGTTCACAGCTGATGGTATATCACCCAGGGGTATTCCAGGCTACGGGTCCGGGACGGTACGGGTGGACTCAGATGAGC
ACGATGAGGAGGGCCTGATAACAGAGGACCTTGATGTGAGGAGGAGGATGGTTGAGAAGAGGAACCTGCGCCTTGAGATG
CTGAAGGATGACACCCTGAAGCCTGAGGTGTACGGTGATAACTCCTCTGCACTGATATGCTGGGGTTCCACCTACTGGCT
GGTACGGGAGGCCATCGAGTCATCCGGTGCAGATGTGAGCATGGTGCACTTCAGCCAGGTCTACCCCCTCCCCCATGACA
CCCTGGAGCTCCTGGAATCATTCGACAGGACCGCTGTGGTTGAGAACAATTACCGCGGACAGTTCGCGGACCTCCTCAAG
CTTGAGGGATTTGAGGCCGATGAAAGGTTCAGGAGGTACGATGGCATGCCCTTCAGCGTTGAGGGGGTTGCCGGATTCAT
CGAGGAGGTTCTCCTATGA

Upstream 100 bases:

>100_bases
TCCTCTGCGGTGAGGCAGGGCAGGGCATACAGACCGTCGAGGCCCTCCTCATAAGGCCTTCAAGGCCACCGGCTACCACA
TATTCTCCTGCAAGGAGTAC

Downstream 100 bases:

>100_bases
GGCCAGAGGATTATGACATGAATGTTGAAATTGCATGGTGTCCAGGATGCGGTAACTTCTCCATCCTGAGGGCCCTCAAG
ATGGCCCTTGCAGACCTGGA

Product: 2-oxoacid:ferredoxin oxidoreductase, alpha subunit

Products: NA

Alternate protein names: 2-ketoglutarate oxidoreductase alpha chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSRVRGGENSTLIRVSSTPVRAFIERVDVLFALSPGAVEHMDGRVKDTLVIADEEFHEEGAISLPIMGEAEKLGGRIFAN
VVAAGAAANLFGVREETFDEAVRSLFERKGPDIVEADLRAGRKGYELGDELREHLEISIEPQPSVREHVVLNGTEAVGIG
CIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLGASYAGARSLVATSGSGFALMEEAVGLAGMI
ETPVVIYIGQRPGPAVGLPTRTAQEDLNLALYAGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQYLADL
YYDLPSPQIGEEPSYHITRTWEGYRRFEFTADGISPRGIPGYGSGTVRVDSDEHDEEGLITEDLDVRRRMVEKRNLRLEM
LKDDTLKPEVYGDNSSALICWGSTYWLVREAIESSGADVSMVHFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLK
LEGFEADERFRRYDGMPFSVEGVAGFIEEVLL

Sequences:

>Translated_512_residues
MSRVRGGENSTLIRVSSTPVRAFIERVDVLFALSPGAVEHMDGRVKDTLVIADEEFHEEGAISLPIMGEAEKLGGRIFAN
VVAAGAAANLFGVREETFDEAVRSLFERKGPDIVEADLRAGRKGYELGDELREHLEISIEPQPSVREHVVLNGTEAVGIG
CIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLGASYAGARSLVATSGSGFALMEEAVGLAGMI
ETPVVIYIGQRPGPAVGLPTRTAQEDLNLALYAGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQYLADL
YYDLPSPQIGEEPSYHITRTWEGYRRFEFTADGISPRGIPGYGSGTVRVDSDEHDEEGLITEDLDVRRRMVEKRNLRLEM
LKDDTLKPEVYGDNSSALICWGSTYWLVREAIESSGADVSMVHFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLK
LEGFEADERFRRYDGMPFSVEGVAGFIEEVLL
>Mature_511_residues
SRVRGGENSTLIRVSSTPVRAFIERVDVLFALSPGAVEHMDGRVKDTLVIADEEFHEEGAISLPIMGEAEKLGGRIFANV
VAAGAAANLFGVREETFDEAVRSLFERKGPDIVEADLRAGRKGYELGDELREHLEISIEPQPSVREHVVLNGTEAVGIGC
IAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLGASYAGARSLVATSGSGFALMEEAVGLAGMIE
TPVVIYIGQRPGPAVGLPTRTAQEDLNLALYAGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQYLADLY
YDLPSPQIGEEPSYHITRTWEGYRRFEFTADGISPRGIPGYGSGTVRVDSDEHDEEGLITEDLDVRRRMVEKRNLRLEML
KDDTLKPEVYGDNSSALICWGSTYWLVREAIESSGADVSMVHFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLKL
EGFEADERFRRYDGMPFSVEGVAGFIEEVLL

Specific function: Unknown

COG id: COG0674

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002880
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005476 [H]

Pfam domain/function: PF01855 POR_N; PF02780 Transketolase_C [H]

EC number: =1.2.7.3 [H]

Molecular weight: Translated: 56280; Mature: 56149

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVRGGENSTLIRVSSTPVRAFIERVDVLFALSPGAVEHMDGRVKDTLVIADEEFHEEG
CCCCCCCCCCEEEEEECCHHHHHHHHHHEEEEECCCCHHHCCCCCEEEEEEECHHHCCCC
AISLPIMGEAEKLGGRIFANVVAAGAAANLFGVREETFDEAVRSLFERKGPDIVEADLRA
CEEECCCCCHHHHCCHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHC
GRKGYELGDELREHLEISIEPQPSVREHVVLNGTEAVGIGCIAGGCRFMSSYPMTPSTPL
CCCCCHHHHHHHHHCEEEECCCCCCCCEEEECCCCEEEEEEEHHHHHHHHCCCCCCCCCE
QVFISENAAEFDMVFEQAEDEIAAINMCLGASYAGARSLVATSGSGFALMEEAVGLAGMI
EEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCC
ETPVVIYIGQRPGPAVGLPTRTAQEDLNLALYAGPGEFPRAILAPGKLEDAPEIAAHAFN
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCHHHHHHHHC
LADRYQIPVFLLSDQYLADLYYDLPSPQIGEEPSYHITRTWEGYRRFEFTADGISPRGIP
CCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCC
GYGSGTVRVDSDEHDEEGLITEDLDVRRRMVEKRNLRLEMLKDDTLKPEVYGDNSSALIC
CCCCCEEEECCCCCCCCCCEECCHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCEEEE
WGSTYWLVREAIESSGADVSMVHFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLK
ECCHHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LEGFEADERFRRYDGMPFSVEGVAGFIEEVLL
HCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHC
>Mature Secondary Structure 
SRVRGGENSTLIRVSSTPVRAFIERVDVLFALSPGAVEHMDGRVKDTLVIADEEFHEEG
CCCCCCCCCEEEEEECCHHHHHHHHHHEEEEECCCCHHHCCCCCEEEEEEECHHHCCCC
AISLPIMGEAEKLGGRIFANVVAAGAAANLFGVREETFDEAVRSLFERKGPDIVEADLRA
CEEECCCCCHHHHCCHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHC
GRKGYELGDELREHLEISIEPQPSVREHVVLNGTEAVGIGCIAGGCRFMSSYPMTPSTPL
CCCCCHHHHHHHHHCEEEECCCCCCCCEEEECCCCEEEEEEEHHHHHHHHCCCCCCCCCE
QVFISENAAEFDMVFEQAEDEIAAINMCLGASYAGARSLVATSGSGFALMEEAVGLAGMI
EEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCC
ETPVVIYIGQRPGPAVGLPTRTAQEDLNLALYAGPGEFPRAILAPGKLEDAPEIAAHAFN
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCHHHHHHHHC
LADRYQIPVFLLSDQYLADLYYDLPSPQIGEEPSYHITRTWEGYRRFEFTADGISPRGIP
CCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCC
GYGSGTVRVDSDEHDEEGLITEDLDVRRRMVEKRNLRLEMLKDDTLKPEVYGDNSSALIC
CCCCCEEEECCCCCCCCCCEECCHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCEEEE
WGSTYWLVREAIESSGADVSMVHFSQVYPLPHDTLELLESFDRTAVVENNYRGQFADLLK
ECCHHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LEGFEADERFRRYDGMPFSVEGVAGFIEEVLL
HCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]