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Identifier: 15678473

GI number: 15678473

Start: 383028

End: 383465

Strand: Direct

Name: Not Available

Synonym: MTH445

Alternate gene names: 15678473

Gene position: 383028-383465 (Clockwise)

Preceding gene: 15678472

Following gene: 15678474

Centisome position: 21.87

GC content: 51.14

Gene sequence:

>438_bases
ATGATGACAGATGCAGATATACTCCTGGTTGAGGATAACCCCACAGACGCGGAACTGACCATAAGGGCCCTGAAGAAGAA
CAACCTTGCCAACAAGCTCCACTGGGTGAAGGACGGGGCAGAGGCCCTTGACTACATATTTGCATCGGGTTCCTACTCTG
ATAGGGATCCGGAGAACCTCCCAAAACTGATCCTCCTGGACCTGAGGATGCCCAAGGTTGACGGCCTCGAGGTACTCCAG
GAGATCAAGAGAAATGATTCAACCAGCAAGATCCCGGTCGTGGTTCTAACATCCTCCAAGGAGGACCGTGACATAGTGGA
AAGCTATAAACTTGGGGTGAACAGCTACGTGAGCAAACCGGTGGAGTTCGATGAATTCATAAGCGCAGTTTCAACCCTTG
GCTTCTACTGGATGATCATAAACCAGCCCCCGGAATAG

Upstream 100 bases:

>100_bases
TAGTCCAGAGAATCATAAAGAGGCATGGTGGAAGGGTCTGGGGTGAAGGAAAGGTTGATGGTGGTGCAACAATATACTTC
ACACTTCCAAAGGTGGTGAA

Downstream 100 bases:

>100_bases
GCATGTCTTGAAGACCAGACACCAGTGAAGAGCCCACAATAAAATTTCCAGGCTTAAGGTGTCTTGAGCTCATTAACCGT
AATGAAGAGGAACCGGAATG

Product: sensory transduction regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MMTDADILLVEDNPTDAELTIRALKKNNLANKLHWVKDGAEALDYIFASGSYSDRDPENLPKLILLDLRMPKVDGLEVLQ
EIKRNDSTSKIPVVVLTSSKEDRDIVESYKLGVNSYVSKPVEFDEFISAVSTLGFYWMIINQPPE

Sequences:

>Translated_145_residues
MMTDADILLVEDNPTDAELTIRALKKNNLANKLHWVKDGAEALDYIFASGSYSDRDPENLPKLILLDLRMPKVDGLEVLQ
EIKRNDSTSKIPVVVLTSSKEDRDIVESYKLGVNSYVSKPVEFDEFISAVSTLGFYWMIINQPPE
>Mature_145_residues
MMTDADILLVEDNPTDAELTIRALKKNNLANKLHWVKDGAEALDYIFASGSYSDRDPENLPKLILLDLRMPKVDGLEVLQ
EIKRNDSTSKIPVVVLTSSKEDRDIVESYKLGVNSYVSKPVEFDEFISAVSTLGFYWMIINQPPE

Specific function: Forms a two-component system with cph1 in which it acts as receiver substrate [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=127, Percent_Identity=33.0708661417323, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1786599, Length=127, Percent_Identity=30.7086614173228, Blast_Score=60, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=120, Percent_Identity=35.8333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.-

Molecular weight: Translated: 16376; Mature: 16376

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDADILLVEDNPTDAELTIRALKKNNLANKLHWVKDGAEALDYIFASGSYSDRDPENL
CCCCCCEEEEECCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PKLILLDLRMPKVDGLEVLQEIKRNDSTSKIPVVVLTSSKEDRDIVESYKLGVNSYVSKP
CEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHCCC
VEFDEFISAVSTLGFYWMIINQPPE
CCHHHHHHHHHHHHEEEEEEECCCC
>Mature Secondary Structure
MMTDADILLVEDNPTDAELTIRALKKNNLANKLHWVKDGAEALDYIFASGSYSDRDPENL
CCCCCCEEEEECCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PKLILLDLRMPKVDGLEVLQEIKRNDSTSKIPVVVLTSSKEDRDIVESYKLGVNSYVSKP
CEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHCCC
VEFDEFISAVSTLGFYWMIINQPPE
CCHHHHHHHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9278513 [H]