Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15678465

GI number: 15678465

Start: 371221

End: 372252

Strand: Direct

Name: Not Available

Synonym: MTH437

Alternate gene names: 15678465

Gene position: 371221-372252 (Clockwise)

Preceding gene: 15678464

Following gene: 15678470

Centisome position: 21.2

GC content: 53.1

Gene sequence:

>1032_bases
GTGGTAATCATGAAGGAACTCATGAAGCGTCTTTCAGTTGCAAGTGGAATCTCTGGATTTGAAGGTGAGGTAAGGGATAT
CATAAGATCTGAACTCGAGGGACATGTCGATGAGATTGAGGAGGACAGCCTCGGTAACATCATCGCCGTGAAGAGGGGGT
CCGGTCCCTCAATCATGCTGGCAGCCCACATGGATGAGATAGGCCTCATGGTGAGGCACATCGATAAGAAGGGATTCATA
AGGTTTTCAAAGATAGGCGGAATCAGTGACCAGATGATACTCAACCAGGCGGTCTGGATCCATGGGGAAAACGGACCCGT
GATGGGTGTCATCGGCTCAAAGCCACCCCACAGGATGAAGGCCTCTGAGAGGAAGAAGGTCACAACCCATGATAACATGT
TCATAGACATAGGCGCCTCTTCAAGGGAGGATGCAGAGGAACTGGTGGCTGTGGGGGACCCTATAACCTTCCATGCGCCC
TACAGTGAACTCGCCAACTCCCGCTTCACAGGGAAGGCCCTTGACAACCGTATAGGCTGCCTTGTAATGGTTGAGGTCCT
AAAGAGGGTTGAAACCGGTGCAACCGTTTATGGTGTTGGAACGGTCCAGGAGGAGGTTGGTCTCAAGGGTGCCAAGACCT
CAGCATTCAGGCTCAACCCGGACATGACCCTGGCCCTGGATGTTACAATAGCCGGGGATCATCCAGGGATGAAGGAGGAG
GAGGCCCCTGCGAAGCTCGAGGGCGGACCCGCCATAATCCTCACCGATGCCAGTGGCAGGGGTATAATAACCCATCCACG
TGTGAAGGACTGGCTACTTGAGACTGCACGTGAGGAGGACATACCTGTCCAGATAGAGGTGAGTGAGGGGGGTACAACCG
ATGCAACCGCCATTCATCTCACAAGGGAGGGGATACCCGCAGGCGTGGTCTCTGTGCCTACAAGGTACATCCATACAACG
GTGAGCATGGCAAGCATGAAGGACATCGAGATGACCGTTGATCTCCTTGTTAAGGCAATTGAAAGATTGTAA

Upstream 100 bases:

>100_bases
GCTGCAGGGATCATACCCCCACAGTATTCAAGGTTCTGGCCCCAGGCCCTCCTGGTTATTCTTGGAATTCTGATAATCAT
AAAGTCAGCTAGATGATCCG

Downstream 100 bases:

>100_bases
CTCCCCTCAATAATTTTTTTAGCTGGACATCAGCTTCGTTTTTCCGTCGAAGTAGAATATGTAGGGGCTGTCACTCCAGC
GGTCATAGACCTCAACAACA

Product: endo-1,4-beta-glucanase

Products: D-glucose; GDP

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVIMKELMKRLSVASGISGFEGEVRDIIRSELEGHVDEIEEDSLGNIIAVKRGSGPSIMLAAHMDEIGLMVRHIDKKGFI
RFSKIGGISDQMILNQAVWIHGENGPVMGVIGSKPPHRMKASERKKVTTHDNMFIDIGASSREDAEELVAVGDPITFHAP
YSELANSRFTGKALDNRIGCLVMVEVLKRVETGATVYGVGTVQEEVGLKGAKTSAFRLNPDMTLALDVTIAGDHPGMKEE
EAPAKLEGGPAIILTDASGRGIITHPRVKDWLLETAREEDIPVQIEVSEGGTTDATAIHLTREGIPAGVVSVPTRYIHTT
VSMASMKDIEMTVDLLVKAIERL

Sequences:

>Translated_343_residues
MVIMKELMKRLSVASGISGFEGEVRDIIRSELEGHVDEIEEDSLGNIIAVKRGSGPSIMLAAHMDEIGLMVRHIDKKGFI
RFSKIGGISDQMILNQAVWIHGENGPVMGVIGSKPPHRMKASERKKVTTHDNMFIDIGASSREDAEELVAVGDPITFHAP
YSELANSRFTGKALDNRIGCLVMVEVLKRVETGATVYGVGTVQEEVGLKGAKTSAFRLNPDMTLALDVTIAGDHPGMKEE
EAPAKLEGGPAIILTDASGRGIITHPRVKDWLLETAREEDIPVQIEVSEGGTTDATAIHLTREGIPAGVVSVPTRYIHTT
VSMASMKDIEMTVDLLVKAIERL
>Mature_343_residues
MVIMKELMKRLSVASGISGFEGEVRDIIRSELEGHVDEIEEDSLGNIIAVKRGSGPSIMLAAHMDEIGLMVRHIDKKGFI
RFSKIGGISDQMILNQAVWIHGENGPVMGVIGSKPPHRMKASERKKVTTHDNMFIDIGASSREDAEELVAVGDPITFHAP
YSELANSRFTGKALDNRIGCLVMVEVLKRVETGATVYGVGTVQEEVGLKGAKTSAFRLNPDMTLALDVTIAGDHPGMKEE
EAPAKLEGGPAIILTDASGRGIITHPRVKDWLLETAREEDIPVQIEVSEGGTTDATAIHLTREGIPAGVVSVPTRYIHTT
VSMASMKDIEMTVDLLVKAIERL

Specific function: Unknown

COG id: COG1363

COG function: function code G; Cellulase M and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M42 family [H]

Homologues:

Organism=Escherichia coli, GI1790332, Length=334, Percent_Identity=41.0179640718563, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082417, Length=344, Percent_Identity=35.1744186046512, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788727, Length=347, Percent_Identity=31.9884726224784, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008007 [H]

Pfam domain/function: PF05343 Peptidase_M42 [H]

EC number: 3.2.1.4

Molecular weight: Translated: 37121; Mature: 37121

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIMKELMKRLSVASGISGFEGEVRDIIRSELEGHVDEIEEDSLGNIIAVKRGSGPSIML
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEE
AAHMDEIGLMVRHIDKKGFIRFSKIGGISDQMILNQAVWIHGENGPVMGVIGSKPPHRMK
EECHHHHHHHHHHCCCCCCEEEECCCCCCHHHEEEEEEEEECCCCCEEEEECCCCCCCCC
ASERKKVTTHDNMFIDIGASSREDAEELVAVGDPITFHAPYSELANSRFTGKALDNRIGC
CCCCCCEEECCCEEEEECCCCCCCHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHCCCHH
LVMVEVLKRVETGATVYGVGTVQEEVGLKGAKTSAFRLNPDMTLALDVTIAGDHPGMKEE
HHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCC
EAPAKLEGGPAIILTDASGRGIITHPRVKDWLLETAREEDIPVQIEVSEGGTTDATAIHL
CCCCEECCCCEEEEECCCCCCEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEE
TREGIPAGVVSVPTRYIHTTVSMASMKDIEMTVDLLVKAIERL
ECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIMKELMKRLSVASGISGFEGEVRDIIRSELEGHVDEIEEDSLGNIIAVKRGSGPSIML
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEE
AAHMDEIGLMVRHIDKKGFIRFSKIGGISDQMILNQAVWIHGENGPVMGVIGSKPPHRMK
EECHHHHHHHHHHCCCCCCEEEECCCCCCHHHEEEEEEEEECCCCCEEEEECCCCCCCCC
ASERKKVTTHDNMFIDIGASSREDAEELVAVGDPITFHAPYSELANSRFTGKALDNRIGC
CCCCCCEEECCCEEEEECCCCCCCHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHCCCHH
LVMVEVLKRVETGATVYGVGTVQEEVGLKGAKTSAFRLNPDMTLALDVTIAGDHPGMKEE
HHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCC
EAPAKLEGGPAIILTDASGRGIITHPRVKDWLLETAREEDIPVQIEVSEGGTTDATAIHL
CCCCEECCCCEEEEECCCCCCEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEE
TREGIPAGVVSVPTRYIHTTVSMASMKDIEMTVDLLVKAIERL
ECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPglucose; H2O

Specific reaction: GDP-glucose + H2O = D-glucose + GDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]