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Identifier: 15678432

GI number: 15678432

Start: 341953

End: 342849

Strand: Direct

Name: Not Available

Synonym: MTH404

Alternate gene names: 15678432

Gene position: 341953-342849 (Clockwise)

Preceding gene: 15678431

Following gene: 15678433

Centisome position: 19.52

GC content: 57.97

Gene sequence:

>897_bases
ATGAGGTTCGATGCGGTGGGCCTTGGAGCCCTCAACATGGACCAGCTCCACATGGTTGAGAGGATAGCAGGCCCGGATGA
GGAGACCTTCGTGAGGGGGCTCGTGGAATCCTGTGGGGGCTCAGCAGCCAACACCATGATAGGCCTCTCAAGGCTCGGTC
TCAGGACAGCCCACATAGGTAAGGTCGCCGATGACAGGGAGGGGGGACTCCTCAGGAGTAACCTCTCATCTGAGGGGGTC
ACGGATTTCACCGTCGTAGCGGATACAGGTAGAAGCGGCCGTGTGATGGGCTTCGTTGACCCTGACGGTAACAGGGCCCT
CTACGTTGACCCTGGAGTCAACGACACACTCAGGGTGGATGAGGTGGCTGATGAGGCCCTTAACACAGAACTGCTGCACC
TCACATCCTTCGCAGGTGATGGCATAAATGTCCAGGTGGAAGTCATTGAGGCACTGGATGAATCCGTGACCGTCAGCCTG
GATCCAGGACACATCTACGCCTCAAGGGGAGTATCTGAGCTGTCAGATATCCTCGAGCGCACCGACATCCTCCTCACAAA
CCAGAGGGAACTTGAGCTGATGACAGGGTCCGCTGACCCTGAGGAGGCAGCATCACTCCTGGGAATCGGGGTGGTTGTGG
TTAAGATGGGCGCCCGAGGCGTCAGGGCATGGGACGGTGAGTCTGTGATGGTGGATGCACTGAGCACCGAATGTGTTGAT
ACGACGGGGGCCGGTGACGCCTTCAATGCTGGCTTCATATATGCCTGGCTCGAGGGCTTTGGCCTTGAGGTTTCATGCCG
TTTTGGAAACTACATAGCATCACGGTGTATCGGAGGATACGGTGCCACAGAATCCCTCCCCGGGACCGGCCCTGGATGTC
CTCAGGAGGTACGCTGA

Upstream 100 bases:

>100_bases
TAGAGGCTGTCTGCAGGTACGATGGGGTCCTGAGGGTATCTGCAGGTAACTATGACGGTAAACTGGGGGACCACAGGATA
GACCTACACGGTGTTCTGGG

Downstream 100 bases:

>100_bases
GGGTTGATCTTTAATGTGCTGGATCCGGGAATCTGGGTGTGCTGAGGCCTGATGTTGATCCCGTGAACCGGAAAAAAATT
TAAGTAAATACGTTTAAAAG

Product: ribokinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIGKVADDREGGLLRSNLSSEGV
TDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVDEVADEALNTELLHLTSFAGDGINVQVEVIEALDESVTVSL
DPGHIYASRGVSELSDILERTDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECVD
TTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESLPGTGPGCPQEVR

Sequences:

>Translated_298_residues
MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIGKVADDREGGLLRSNLSSEGV
TDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVDEVADEALNTELLHLTSFAGDGINVQVEVIEALDESVTVSL
DPGHIYASRGVSELSDILERTDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECVD
TTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESLPGTGPGCPQEVR
>Mature_298_residues
MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIGKVADDREGGLLRSNLSSEGV
TDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVDEVADEALNTELLHLTSFAGDGINVQVEVIEALDESVTVSL
DPGHIYASRGVSELSDILERTDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECVD
TTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESLPGTGPGCPQEVR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=257, Percent_Identity=28.7937743190661, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790193, Length=295, Percent_Identity=28.4745762711864, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 31407; Mature: 31407

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIG
CCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCC
KVADDREGGLLRSNLSSEGVTDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVD
CCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEECCCCCCCEEHH
EVADEALNTELLHLTSFAGDGINVQVEVIEALDESVTVSLDPGHIYASRGVSELSDILER
HHHHHHHCCEEEEEEHCCCCCCEEEEEEEECCCCCEEEEECCCEEEHHCCHHHHHHHHHH
TDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECVD
HHEEEECCCEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCEEECCCEEEEEECCCHHCC
TTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESLPGTGPGCPQEVR
CCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIG
CCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCC
KVADDREGGLLRSNLSSEGVTDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVD
CCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEECCCCCCCEEHH
EVADEALNTELLHLTSFAGDGINVQVEVIEALDESVTVSLDPGHIYASRGVSELSDILER
HHHHHHHCCEEEEEEHCCCCCCEEEEEEEECCCCCEEEEECCCEEEHHCCHHHHHHHHHH
TDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECVD
HHEEEECCCEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCEEECCCEEEEEECCCHHCC
TTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESLPGTGPGCPQEVR
CCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]