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The map label for this gene is rpl7ae

Identifier: 15678283

GI number: 15678283

Start: 198172

End: 198564

Strand: Direct

Name: rpl7ae

Synonym: MTH255

Alternate gene names: 15678283

Gene position: 198172-198564 (Clockwise)

Preceding gene: 15678282

Following gene: 15678284

Centisome position: 11.32

GC content: 47.07

Gene sequence:

>393_bases
ATGAAAAAGGAGGTAAACAGCATGGCAAAAGCAATATACGTGAAATTTGATGTACCAAAGGAACTGGCTGACAAGGCCGC
AGAGGCACTTGAAATAGCCAGGGAGACAGGTAAGGTATCCAAGGGTACAAATGAGGTTACCAAGGCTGTCGAGAGGGGAG
TTGCTCAGCTCGTATTAATAGCTGAGGACGTTGAACCTGCAGAGATCGTTGCTCACCTTCCACTCCTCGCAGAGGAAAAG
GAAATACCATACATATACATCCCAACAAAGGATGAACTGGGTGCAGCCGCAGGTCTGAACGTTGGAACAGCATCATCAGC
CATCGTTGAGGCAGGCGACGCCGAGGACCTCATAAAAGAGATAATAGAAAAGGTCGAAGAACTTAAGAAATAG

Upstream 100 bases:

>100_bases
ACCGAGAACATATAAAGGTACTCACCCACTTCATGTTAATCCATAACTTGGATTATTGATCCAGATTGGTGTAATTACCG
ATGGATGGTAGAAAAACCAG

Downstream 100 bases:

>100_bases
ATGAAAGGCACTAAAAGCCTTTCAATTTCAATTTAATAAAGGTGATTTAATGGATGACGCAACTCCAGCAGAGGTTATTG
AGGTTCTCAAGAGAACCGGG

Product: 50S ribosomal protein L7Ae

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKKEVNSMAKAIYVKFDVPKELADKAAEALEIARETGKVSKGTNEVTKAVERGVAQLVLIAEDVEPAEIVAHLPLLAEEK
EIPYIYIPTKDELGAAAGLNVGTASSAIVEAGDAEDLIKEIIEKVEELKK

Sequences:

>Translated_130_residues
MKKEVNSMAKAIYVKFDVPKELADKAAEALEIARETGKVSKGTNEVTKAVERGVAQLVLIAEDVEPAEIVAHLPLLAEEK
EIPYIYIPTKDELGAAAGLNVGTASSAIVEAGDAEDLIKEIIEKVEELKK
>Mature_130_residues
MKKEVNSMAKAIYVKFDVPKELADKAAEALEIARETGKVSKGTNEVTKAVERGVAQLVLIAEDVEPAEIVAHLPLLAEEK
EIPYIYIPTKDELGAAAGLNVGTASSAIVEAGDAEDLIKEIIEKVEELKK

Specific function: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs [H]

COG id: COG1358

COG function: function code J; Ribosomal protein HS6-type (S12/L30/L7a)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L7Ae family [H]

Homologues:

Organism=Homo sapiens, GI4826860, Length=80, Percent_Identity=37.5, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI51317376, Length=80, Percent_Identity=37.5, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI8923444, Length=109, Percent_Identity=31.1926605504587, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555988, Length=90, Percent_Identity=32.2222222222222, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565833, Length=93, Percent_Identity=40.8602150537634, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320809, Length=109, Percent_Identity=34.8623853211009, Blast_Score=77, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319993, Length=94, Percent_Identity=37.2340425531915, Blast_Score=74, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864298, Length=110, Percent_Identity=35.4545454545455, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356151, Length=125, Percent_Identity=32, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004038
- InterPro:   IPR018492
- InterPro:   IPR022481
- InterPro:   IPR000948 [H]

Pfam domain/function: PF01248 Ribosomal_L7Ae [H]

EC number: NA

Molecular weight: Translated: 13971; Mature: 13971

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEVNSMAKAIYVKFDVPKELADKAAEALEIARETGKVSKGTNEVTKAVERGVAQLVLI
CCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEDVEPAEIVAHLPLLAEEKEIPYIYIPTKDELGAAAGLNVGTASSAIVEAGDAEDLIKE
HCCCCHHHHHHHCCHHCCCCCCCEEEECCCHHHCCCCCCCCCCCCHHHHCCCCHHHHHHH
IIEKVEELKK
HHHHHHHHCC
>Mature Secondary Structure
MKKEVNSMAKAIYVKFDVPKELADKAAEALEIARETGKVSKGTNEVTKAVERGVAQLVLI
CCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEDVEPAEIVAHLPLLAEEKEIPYIYIPTKDELGAAAGLNVGTASSAIVEAGDAEDLIKE
HCCCCHHHHHHHCCHHCCCCCCCEEEECCCHHHCCCCCCCCCCCCHHHHCCCCHHHHHHH
IIEKVEELKK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]