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Identifier: 15678186

GI number: 15678186

Start: 104860

End: 105375

Strand: Direct

Name: Not Available

Synonym: MTH158

Alternate gene names: 15678186

Gene position: 104860-105375 (Clockwise)

Preceding gene: 15678185

Following gene: 15678187

Centisome position: 5.99

GC content: 52.33

Gene sequence:

>516_bases
ATGGTAAGTGAAAGGATGCAGGAGGCGCTAAACAGGCAGCTAAATGCTGAGCTCTACTCAGCATATCTCTACCTTTCAAT
GGCAGCCTACTACGAGGCCTCCGATCTTCCTGGATTCGCAAACTGGATGCGTGTACAGGCCCAGGAGGAGCTTTCACACG
CAATGAAATTCTACGACTACCTTGTGCAGAGGGGTGCAAGGGTCGTACTGGATGAGATAGAGAAACCACCATTTGAGTGG
GAATCACCACTTGAGGTGGCCAAGCATGTCCTTGAACATGAGAAGAAGGTCACAGGACTCATAAATGACCTTGTGGACCT
CGCCATCTCAGAGAGGGATCATGCAACCAACAACTTCCTCCAGTGGTTCGTTGCAGAGCAGGTTGAGGAGGAGGAATCAG
CAGGGAGCCTTCTCCAGAGGGTGCGCCTCGCATCAGACTCACCCAGCGGACTCCTCATGCTGGATGCAGAACTGGCAAAG
AGGGTCTACAATCCACCCGCAGATAAGGGGGAATGA

Upstream 100 bases:

>100_bases
ATGTCGAATACCTTGAATCCGTCCTTGTGAAGGGTCTCCCGGTGGAGGAGGACCTTCAGAGGGTGGATGAACTTGCCATG
AAGATAAAGGGGGTGAATGA

Downstream 100 bases:

>100_bases
GCTATGGGGGAGAAGGTATACGAACTCAGAAAGATAAAGAAAAAGGGAAGGGGAATGCCCCTCATAGGGGATAAATTCCC
GGAGATGGAGGTCCAGACGA

Product: ferritin like protein (RsgA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MVSERMQEALNRQLNAELYSAYLYLSMAAYYEASDLPGFANWMRVQAQEELSHAMKFYDYLVQRGARVVLDEIEKPPFEW
ESPLEVAKHVLEHEKKVTGLINDLVDLAISERDHATNNFLQWFVAEQVEEEESAGSLLQRVRLASDSPSGLLMLDAELAK
RVYNPPADKGE

Sequences:

>Translated_171_residues
MVSERMQEALNRQLNAELYSAYLYLSMAAYYEASDLPGFANWMRVQAQEELSHAMKFYDYLVQRGARVVLDEIEKPPFEW
ESPLEVAKHVLEHEKKVTGLINDLVDLAISERDHATNNFLQWFVAEQVEEEESAGSLLQRVRLASDSPSGLLMLDAELAK
RVYNPPADKGE
>Mature_171_residues
MVSERMQEALNRQLNAELYSAYLYLSMAAYYEASDLPGFANWMRVQAQEELSHAMKFYDYLVQRGARVVLDEIEKPPFEW
ESPLEVAKHVLEHEKKVTGLINDLVDLAISERDHATNNFLQWFVAEQVEEEESAGSLLQRVRLASDSPSGLLMLDAELAK
RVYNPPADKGE

Specific function: May alleviate iron toxicity in the presence of oxygen [H]

COG id: COG1528

COG function: function code P; Ferritin-like protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ferritin-like diiron domain [H]

Homologues:

Organism=Homo sapiens, GI56682959, Length=147, Percent_Identity=36.0544217687075, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI29126241, Length=131, Percent_Identity=38.1679389312977, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI13994244, Length=147, Percent_Identity=31.2925170068027, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788216, Length=159, Percent_Identity=38.3647798742138, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1788212, Length=141, Percent_Identity=28.3687943262411, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558956, Length=127, Percent_Identity=33.8582677165354, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506345, Length=128, Percent_Identity=35.15625, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641673, Length=133, Percent_Identity=30.8270676691729, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009040
- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR008331
- InterPro:   IPR001519 [H]

Pfam domain/function: PF00210 Ferritin [H]

EC number: =1.16.3.1 [H]

Molecular weight: Translated: 19565; Mature: 19565

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50905 FERRITIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSERMQEALNRQLNAELYSAYLYLSMAAYYEASDLPGFANWMRVQAQEELSHAMKFYDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVQRGARVVLDEIEKPPFEWESPLEVAKHVLEHEKKVTGLINDLVDLAISERDHATNNFL
HHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QWFVAEQVEEEESAGSLLQRVRLASDSPSGLLMLDAELAKRVYNPPADKGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVSERMQEALNRQLNAELYSAYLYLSMAAYYEASDLPGFANWMRVQAQEELSHAMKFYDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVQRGARVVLDEIEKPPFEWESPLEVAKHVLEHEKKVTGLINDLVDLAISERDHATNNFL
HHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QWFVAEQVEEEESAGSLLQRVRLASDSPSGLLMLDAELAKRVYNPPADKGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA