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Identifier: 15678076

GI number: 15678076

Start: 25356

End: 26156

Strand: Direct

Name: Not Available

Synonym: MTH47

Alternate gene names: 15678076

Gene position: 25356-26156 (Clockwise)

Preceding gene: 15678075

Following gene: 15678077

Centisome position: 1.45

GC content: 50.69

Gene sequence:

>801_bases
ATGATCATTCTCAAGCTTGGTGGAAGTGTAATTACCAGGAAGGACTCTGAGGAACCTGCAATAGACAGGGATAACCTTGA
AAGGATAGCCTCAGAGATAGGGAACGCTTCGCCATCATCATTGATGATAGTGCACGGCGCAGGGTCCTTTGGCCACCCAT
TTGCAGGTGAGTACAGGATAGGCTCGGAGATAGAGAATGAGGAGGACCTCAGGCGCCGGAGGTTTGGATTTGCACTGACC
CAGAACTGGGTTAAAAAGCTTAACAGCCATGTATGCGACGCACTCCTTGCTGAGGGAATTCCAGCAGTTTCAATGCAGCC
ATCAGCTTTCATAAGGGCCCATGCTGGCCGCATAAGCCACGCGGATATCTCACTGATCAGATCCTACCTTGAGGAGGGTA
TGGTACCGGTGGTCTACGGTGACGTTGTACTTGACTCAGACAGGAGGTTGAAATTTTCTGTCATATCAGGAGACCAGCTG
ATAAACCACTTCTCCCTGAGGCTGATGCCGGAGAGGGTCATACTCGGGACAGATGTGGACGGGGTATACACCAGGAACCC
TAAGAAGCACCCCGATGCAAGGCTCCTTGATGTTATAGGATCACTCGATGACCTTGAATCCCTTGACGGGACACTTAACA
CTGATGTGACGGGTGGAATGGTCGGTAAGATAAGGGAACTCCTTCTGCTTGCAGAGAAGGGTGTGGAATCTGAAATAATT
AATGCTGCAGTGCCCGGAAATATTGAGAGGGCCCTCCTGGGAGAGGAGGTACGGGGCACAAGAATCACAGGGAAACATTG
A

Upstream 100 bases:

>100_bases
TGTGGATGATGTTGTCACGGCCCTTAACAGGAACTGGAAAGCCATGAGGGCAGAGTTTTCGGTTAAGGGACTCATCTAAT
ATTCACAGGGTGCATATGTA

Downstream 100 bases:

>100_bases
GGACATTCACGATTATCAATCAACATTCAAAGGAATTTATAGGGTGATGGAAAATTTTTAAGGGCGTTAAAATATGATTT
CGGATAGGAAACTGGAGCAT

Product: hypothetical protein

Products: ADP; L-Glutamate 5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIILKLGGSVITRKDSEEPAIDRDNLERIASEIGNASPSSLMIVHGAGSFGHPFAGEYRIGSEIENEEDLRRRRFGFALT
QNWVKKLNSHVCDALLAEGIPAVSMQPSAFIRAHAGRISHADISLIRSYLEEGMVPVVYGDVVLDSDRRLKFSVISGDQL
INHFSLRLMPERVILGTDVDGVYTRNPKKHPDARLLDVIGSLDDLESLDGTLNTDVTGGMVGKIRELLLLAEKGVESEII
NAAVPGNIERALLGEEVRGTRITGKH

Sequences:

>Translated_266_residues
MIILKLGGSVITRKDSEEPAIDRDNLERIASEIGNASPSSLMIVHGAGSFGHPFAGEYRIGSEIENEEDLRRRRFGFALT
QNWVKKLNSHVCDALLAEGIPAVSMQPSAFIRAHAGRISHADISLIRSYLEEGMVPVVYGDVVLDSDRRLKFSVISGDQL
INHFSLRLMPERVILGTDVDGVYTRNPKKHPDARLLDVIGSLDDLESLDGTLNTDVTGGMVGKIRELLLLAEKGVESEII
NAAVPGNIERALLGEEVRGTRITGKH
>Mature_266_residues
MIILKLGGSVITRKDSEEPAIDRDNLERIASEIGNASPSSLMIVHGAGSFGHPFAGEYRIGSEIENEEDLRRRRFGFALT
QNWVKKLNSHVCDALLAEGIPAVSMQPSAFIRAHAGRISHADISLIRSYLEEGMVPVVYGDVVLDSDRRLKFSVISGDQL
INHFSLRLMPERVILGTDVDGVYTRNPKKHPDARLLDVIGSLDDLESLDGTLNTDVTGGMVGKIRELLLLAEKGVESEII
NAAVPGNIERALLGEEVRGTRITGKH

Specific function: Catalyzes The Transfer Of A Phosphate Group To Glutamate To Form Glutamate 5-Phosphate Which Rapidly Cyclizes To 5- Oxoproline. [C]

COG id: COG1608

COG function: function code R; Predicted archaeal kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: 2.7.2.11 [C]

Molecular weight: Translated: 29085; Mature: 29085

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILKLGGSVITRKDSEEPAIDRDNLERIASEIGNASPSSLMIVHGAGSFGHPFAGEYRI
CEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEC
GSEIENEEDLRRRRFGFALTQNWVKKLNSHVCDALLAEGIPAVSMQPSAFIRAHAGRISH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCH
ADISLIRSYLEEGMVPVVYGDVVLDSDRRLKFSVISGDQLINHFSLRLMPERVILGTDVD
HHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHEECCCEEEEECCCC
GVYTRNPKKHPDARLLDVIGSLDDLESLDGTLNTDVTGGMVGKIRELLLLAEKGVESEII
CCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NAAVPGNIERALLGEEVRGTRITGKH
HCCCCCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIILKLGGSVITRKDSEEPAIDRDNLERIASEIGNASPSSLMIVHGAGSFGHPFAGEYRI
CEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEC
GSEIENEEDLRRRRFGFALTQNWVKKLNSHVCDALLAEGIPAVSMQPSAFIRAHAGRISH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCH
ADISLIRSYLEEGMVPVVYGDVVLDSDRRLKFSVISGDQLINHFSLRLMPERVILGTDVD
HHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHEECCCEEEEECCCC
GVYTRNPKKHPDARLLDVIGSLDDLESLDGTLNTDVTGGMVGKIRELLLLAEKGVESEII
CCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NAAVPGNIERALLGEEVRGTRITGKH
HCCCCCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.007 {glutamate}} 2 {ATP}} 0.4 {ATP}} [C]

Substrates: ATP; L-Glutamate [C]

Specific reaction: ATP + L-Glutamate --> ADP + L-Glutamate 5-phosphate [C]

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]