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Identifier: 15678071

GI number: 15678071

Start: 21452

End: 21637

Strand: Direct

Name: Not Available

Synonym: MTH42

Alternate gene names: 15678071

Gene position: 21452-21637 (Clockwise)

Preceding gene: 15678070

Following gene: 15678072

Centisome position: 1.22

GC content: 45.7

Gene sequence:

>186_bases
ATGCATATGGCGTCAAAAAAACTCACACGTTTTGAAAGGGCTAGGCTGATAGGTGCCAGGGCACTCCAGATATCAATGGG
TGCAAGACCACTCGTTGAGATCAAGGAGTCACTGGACCCTGTTGATATAGCCAGAAAGGAACTTGAAAAGAAGGTCATGC
CACTGGACGTTAGAAGAGACAAATAA

Upstream 100 bases:

>100_bases
GATGGTCAGCACCGGAACGCTGGAGACCCGAGTTCAAATCTCGGCGGTCCCATCAAATCGAATCCAAGAACCTCTATTTT
AATGTTTTTCTTGGAGGCAT

Downstream 100 bases:

>100_bases
ACTCTAATAAACCACTATTTTTCAGTCTAGAGTTTATTATGAGGTGTTTTAATGGAAAGTATTATTGAAGATGTTAGAGT
AAGGAAAATTCTTGACAGCA

Product: DNA-dependent RNA polymerase, subunit K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 61; Mature: 61

Protein sequence:

>61_residues
MHMASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRRDK

Sequences:

>Translated_61_residues
MHMASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRRDK
>Mature_61_residues
MHMASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRRDK

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG1758

COG function: function code K; DNA-directed RNA polymerase, subunit K/omega

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family

Homologues:

Organism=Caenorhabditis elegans, GI17531543, Length=58, Percent_Identity=50, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOK_METTH (O26148)

Other databases:

- EMBL:   AE000666
- PIR:   F69154
- RefSeq:   NP_275185.1
- ProteinModelPortal:   O26148
- SMR:   O26148
- STRING:   O26148
- GeneID:   1470004
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH42
- NMPDR:   fig|187420.1.peg.40
- eggNOG:   arNOG14104
- HOGENOM:   HBG646526
- OMA:   FRYTRFE
- ProtClustDB:   PRK01099
- BioCyc:   MTHE187420:MTH42-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_00192
- InterPro:   IPR020708
- InterPro:   IPR006111
- InterPro:   IPR006110
- InterPro:   IPR012293
- Gene3D:   G3DSA:3.90.940.10
- PANTHER:   PTHR10773

Pfam domain/function: PF01192 RNA_pol_Rpb6; SSF63562 RNA_pol_omega

EC number: =2.7.7.6

Molecular weight: Translated: 7044; Mature: 7044

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: PS01111 RNA_POL_K_14KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRRD
CCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
K
C
>Mature Secondary Structure
MHMASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRRD
CCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463