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The map label for this gene is sipL

Identifier: 15674240

GI number: 15674240

Start: 2350328

End: 2350954

Strand: Direct

Name: sipL

Synonym: L0337

Alternate gene names: 15674240

Gene position: 2350328-2350954 (Clockwise)

Preceding gene: 15674239

Following gene: 15674245

Centisome position: 99.35

GC content: 37.64

Gene sequence:

>627_bases
ATGATGAAATTTTTAAAAGAGTGGGGATTATTTCTCTTTATAATTATCGCTATTCTTCTCTCACTTGTCTTTCTTTGGTC
ACTTGTTGTTGTGGATGGTCATTCAATGGACCCAACTTTAGCTGACAAGGAACGTCTGGTTATTGTAAGAAAATCAACCA
TTAATCGTTTTGATATTGTTGTTGCCAAAGAAGAAACAGCCGATGGTTCAACTAAAGATATCGTGAAACGTGTCATTGGA
ATGCCTGGAGATACTATAAAATTCGACCACGACCAACTCACAATCAATAACAAAGTTTATCCAGAAAATTATCTCAAAGA
TTACCAAAAGCAACTTGCTGACGGTCAGTTGGAAAAAACTTACGGTAAGTATCCTTTAACAAATGCACTCAGTGAACAAA
ACCGCAGTTTGTTTGTTAGTTTAGCTCAAAGCACCAAAGCATTTACCACTGACAGCACTGGTAACCCAACCTTTACAGTA
AAAGTTCCTGAGGGACAATACTTCCTGATGGGAGATAATCGGGTAGTTTCTCAAGATAGTCGCGCAGTTGGAACTTTCAA
ACGTTCAGCAATTGTTGGTGAAGCGAAATTACGAGTGTGGCCACTCAACAAAATTTCTTTCTTTTAA

Upstream 100 bases:

>100_bases
TCAAAAGTCAGGGAGTTGATGCTCTGAATCAGTTAGCAAAACTTCATTTTGCTAATACACAAAAAGCGATTAAAATCGCT
CAATTATAGAAAGTAAAATT

Downstream 100 bases:

>100_bases
GTGAATAAATAGAAAAAGTTACTGACAGAATGTCCTGTCAGTAACTTTTTTATTTGTCATTAAATATATTTCCCAATTGA
ACATCAATTGAGCGGTTAGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MMKFLKEWGLFLFIIIAILLSLVFLWSLVVVDGHSMDPTLADKERLVIVRKSTINRFDIVVAKEETADGSTKDIVKRVIG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGKYPLTNALSEQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPEGQYFLMGDNRVVSQDSRAVGTFKRSAIVGEAKLRVWPLNKISFF

Sequences:

>Translated_208_residues
MMKFLKEWGLFLFIIIAILLSLVFLWSLVVVDGHSMDPTLADKERLVIVRKSTINRFDIVVAKEETADGSTKDIVKRVIG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGKYPLTNALSEQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPEGQYFLMGDNRVVSQDSRAVGTFKRSAIVGEAKLRVWPLNKISFF
>Mature_208_residues
MMKFLKEWGLFLFIIIAILLSLVFLWSLVVVDGHSMDPTLADKERLVIVRKSTINRFDIVVAKEETADGSTKDIVKRVIG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGKYPLTNALSEQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPEGQYFLMGDNRVVSQDSRAVGTFKRSAIVGEAKLRVWPLNKISFF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23551; Mature: 23551

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKFLKEWGLFLFIIIAILLSLVFLWSLVVVDGHSMDPTLADKERLVIVRKSTINRFDIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEE
VAKEETADGSTKDIVKRVIGMPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKT
EEECCCCCCCHHHHHHHHHCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHCCCCHHHH
YGKYPLTNALSEQNRSLFVSLAQSTKAFTTDSTGNPTFTVKVPEGQYFLMGDNRVVSQDS
CCCCCCHHHHHHCCCEEEEEEHHCCCEEECCCCCCCEEEEEECCCCEEEEECCEEECCCC
RAVGTFKRSAIVGEAKLRVWPLNKISFF
HHHHHHHHHHEECCCEEEEEECHHCCCC
>Mature Secondary Structure
MMKFLKEWGLFLFIIIAILLSLVFLWSLVVVDGHSMDPTLADKERLVIVRKSTINRFDIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEE
VAKEETADGSTKDIVKRVIGMPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKT
EEECCCCCCCHHHHHHHHHCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHCCCCHHHH
YGKYPLTNALSEQNRSLFVSLAQSTKAFTTDSTGNPTFTVKVPEGQYFLMGDNRVVSQDS
CCCCCCHHHHHHCCCEEEEEEHHCCCEEECCCCCCCEEEEEECCCCEEEEECCEEECCCC
RAVGTFKRSAIVGEAKLRVWPLNKISFF
HHHHHHHHHHEECCCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272867; 11463916 [H]