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The map label for this gene is uppP

Identifier: 15674174

GI number: 15674174

Start: 2275196

End: 2276050

Strand: Reverse

Name: uppP

Synonym: L58643

Alternate gene names: 15674174

Gene position: 2276050-2275196 (Counterclockwise)

Preceding gene: 15674176

Following gene: 15674173

Centisome position: 96.21

GC content: 36.37

Gene sequence:

>855_bases
ATGGATTTTATTCGTGCCATTATTTTAGGTGTTATTGAAGGAATCACTGAGTGGTTACCTATTTCCTCAACAGGACATTT
GATTATTGCTGATGAATTTATTCGTCTTAATCAATCAGCAGCTTTTAAAGAAATGTTTGATGTTGTGATTCAGCTAGGAG
CAATTTTGTCAGTTGTTGTTCTTTATTTTCATAAACTGAATCCATTTAATAAGTTAAATCCAGCTGACAAACAAAAAACC
CCACGTGAAATTCAATTAACTTGGCGTTTGTGGTTGAAAGTTTTGATTGCGGCTTTACCAGCAGCGATTATTGGTTTACC
ACTTAATGACTGGTTGGACAAACATTTTTACCATTTTGTTCCTGTTGCCTTCATGTTAATTATTTATGGGGTAGCATTTA
TTGTCATTGAGCGTCGGTGGGTACCAAATCATGAATTTTCCGTAATGAATATTGACCGTTTGCCTTATCGTGCCGCTCTT
TATATTGGATTATTCCAAGTGCTGTCTTTACTTCCAGGGACATCGCGTTCAGGTGCGACAATTGTCGGTGCTTTATTAGT
TGGTGTAAGTCGTGAAGTTGCCGCAGAATTTACCTTTTTCTTGGGTATTCCAGTTATGTTTGGGGCTAGTTTCATCAAAA
TACTTCACTTTTTCAAAAATGGGAATTCTTTAAGTTTTGAACAATTTGGGGTCTTGTTAGTAGCTTGTATAGTTGCCTTT
GGGGTATCAATGGTTGCCATCAAGTTCTTGACCGATTATGTGAAAAAACACGATTTTACTTTCTTTGGGAAATATCGGAT
TGTGTTAGGGATTATCCTTCTTATTTATGCAATGTTTAGAGCCTTTTTGGGCTGA

Upstream 100 bases:

>100_bases
AAGTTTATTCATTTGTCATTTATGATATACTTATGAGGATAGGACTGCTATGTCAGTCAATAAAATCAGTCTTTTTACTG
AAATTTTCTAGGAGCAAAAT

Downstream 100 bases:

>100_bases
GAATGAGATAAATTATGCCAACTCTCTTTAGTTGGTATTTTTTATTTTAAAATAGTTCTCTTTGCTGAGGGAAAGTTTAA
ATGTATTCTTGCTAAAAATA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MDFIRAIILGVIEGITEWLPISSTGHLIIADEFIRLNQSAAFKEMFDVVIQLGAILSVVVLYFHKLNPFNKLNPADKQKT
PREIQLTWRLWLKVLIAALPAAIIGLPLNDWLDKHFYHFVPVAFMLIIYGVAFIVIERRWVPNHEFSVMNIDRLPYRAAL
YIGLFQVLSLLPGTSRSGATIVGALLVGVSREVAAEFTFFLGIPVMFGASFIKILHFFKNGNSLSFEQFGVLLVACIVAF
GVSMVAIKFLTDYVKKHDFTFFGKYRIVLGIILLIYAMFRAFLG

Sequences:

>Translated_284_residues
MDFIRAIILGVIEGITEWLPISSTGHLIIADEFIRLNQSAAFKEMFDVVIQLGAILSVVVLYFHKLNPFNKLNPADKQKT
PREIQLTWRLWLKVLIAALPAAIIGLPLNDWLDKHFYHFVPVAFMLIIYGVAFIVIERRWVPNHEFSVMNIDRLPYRAAL
YIGLFQVLSLLPGTSRSGATIVGALLVGVSREVAAEFTFFLGIPVMFGASFIKILHFFKNGNSLSFEQFGVLLVACIVAF
GVSMVAIKFLTDYVKKHDFTFFGKYRIVLGIILLIYAMFRAFLG
>Mature_284_residues
MDFIRAIILGVIEGITEWLPISSTGHLIIADEFIRLNQSAAFKEMFDVVIQLGAILSVVVLYFHKLNPFNKLNPADKQKT
PREIQLTWRLWLKVLIAALPAAIIGLPLNDWLDKHFYHFVPVAFMLIIYGVAFIVIERRWVPNHEFSVMNIDRLPYRAAL
YIGLFQVLSLLPGTSRSGATIVGALLVGVSREVAAEFTFFLGIPVMFGASFIKILHFFKNGNSLSFEQFGVLLVACIVAF
GVSMVAIKFLTDYVKKHDFTFFGKYRIVLGIILLIYAMFRAFLG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=37.7358490566038, Blast_Score=151, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_LACLA (Q9CDM7)

Other databases:

- EMBL:   AE005176
- PIR:   H86898
- RefSeq:   NP_268349.1
- GeneID:   1115870
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L58643
- NMPDR:   fig|272623.1.peg.2247
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   LLAC272623:L58643-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 32080; Mature: 32080

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfe01418)-; HASH(0xfb18358)-; HASH(0xf4fdadc)-; HASH(0xd37e0a0)-; HASH(0x1034e590)-; HASH(0xfeb16ec)-; HASH(0x106542c4)-; HASH(0xfc9ba4c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471