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The map label for this gene is tsf

Identifier: 15674134

GI number: 15674134

Start: 2226193

End: 2227221

Strand: Reverse

Name: tsf

Synonym: L0376

Alternate gene names: 15674134

Gene position: 2227221-2226193 (Counterclockwise)

Preceding gene: 15674135

Following gene: 15674133

Centisome position: 94.15

GC content: 39.26

Gene sequence:

>1029_bases
ATGGCAGTAACAGCAGCTCAAGTAAAAGAATTACGTGAAAAAACTGGTGCAGGAATCATGGACGCTAAACGCGCTCTTGT
TGAAACTGACGGAAATATGGAAGCAGCAGCAGAACTTCTTCGTGAAAAAGGGATTGCGAAAGCAGCTAAAAAAGCTGATC
GTGTAGCAGCTGAAGGACTTACAGGAATTGCTGTAAACGGAAATGTTGCAGCGATTGTTGAATTGAACTCAGAAACAGAC
TTTGTAGCTAAAAATGATCAATTTGTTGCCTTGGTTAAAGAAACAGCAGAACTTATTGCGTCTAAAAAACCAGCAACTAA
CGAAGAAGCGTTGGCACTTGAAACAGCTTCAGGTATTACTCTTGAAGCAGAACTTGTTCAAGCGACTGCTACAATCGGAG
AAAAAATTACTTTCCGTCGTTTTGCAGTAATTGAAAAAACTGATGCTCAACACTTTGGGGCTTACCAACATAACGGTGGT
AAAATTGGGGTTGTTTCTGTCGTTGAAGGTGCAGATGAAACACTTGCTAAACAAGTATCAATGCATATTGCTGCAATGAA
CCCTACTGTTCTTTCAGCTGATGAACTTGATTCAGAATTTGTTAAAGCTGAATTAGCACAAATGAACCACAAGATTGATG
AAGACAATGCTAGCCGTGTACTTGTTAACAAACCAGAACTTCCACACCATGAATTTGGTTCTAAGAGCCAATTGACAGAA
GAAGTTCTTGCAGCAGCGAAAGCTTCATTTGAAGAAGAACTTAAAGCTGAAGGAAAACCAGAAAAAATCTGGGACAAAAT
TCTTCCAGGTAAAATGGCTAAATTCATCGTTGACAATACAAAAGTTGACCAACAATTTGCTCTTCTTGCACAACTTTACA
TCATGGATGACAGCAAAACAGTCGAAGCTTTCCTTGAATCAAAAGGAGCTAAAGCAATTGCATTCACACGTTTTGAAGTT
GGTGAAGGAATTGAAAAAGCTGAAACAGACTTTGCAGCAGAAGTTGAAGCAGCAAAAGCAGGACTTTAA

Upstream 100 bases:

>100_bases
ATTAAGTAACTACAACAGGCGAGGCCTTACGCCTCGCCTGTTTTTTTAAATAAAACTACTGTCAATACTGACAGAAAAAA
ACACATAGGAGATTTACAAA

Downstream 100 bases:

>100_bases
TTTAATTAAAAAGCAGCCTCTAGAGGTTGCTTTTTTTATTTTGAAAATAAAAAAGGGCTTTTCGGTTAGAAAACTAAGAA
AATAGTGTATTTCTTTGACG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETD
FVAKNDQFVALVKETAELIASKKPATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGG
KIGVVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTE
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEV
GEGIEKAETDFAAEVEAAKAGL

Sequences:

>Translated_342_residues
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETD
FVAKNDQFVALVKETAELIASKKPATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGG
KIGVVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTE
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEV
GEGIEKAETDFAAEVEAAKAGL
>Mature_341_residues
AVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETDF
VAKNDQFVALVKETAELIASKKPATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGK
IGVVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTEE
VLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVG
EGIEKAETDFAAEVEAAKAGL

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=225, Percent_Identity=28, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786366, Length=335, Percent_Identity=37.3134328358209, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17561440, Length=211, Percent_Identity=27.4881516587678, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921466, Length=212, Percent_Identity=31.1320754716981, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_LACLA (Q9CDR5)

Other databases:

- EMBL:   AE005176
- PIR:   H86893
- RefSeq:   NP_268309.1
- ProteinModelPortal:   Q9CDR5
- SMR:   Q9CDR5
- PhosSite:   Q9CDR5
- GeneID:   1115829
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0376
- NMPDR:   fig|272623.1.peg.2207
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   LLAC272623:L0376-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 36670; Mature: 36539

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGL
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
TGIAVNGNVAAIVELNSETDFVAKNDQFVALVKETAELIASKKPATNEEALALETASGIT
CEEEECCCEEEEEEECCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEECCCCCE
LEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIGVVSVVEGADETLAKQVS
EHHHHHHHHHHHCCHHHHHHEEEEECCCHHHCCCEECCCCCEEEEEEECCCHHHHHHHHH
MHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTE
HHHEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKT
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCHH
VEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKAGL
HHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
TGIAVNGNVAAIVELNSETDFVAKNDQFVALVKETAELIASKKPATNEEALALETASGIT
CEEEECCCEEEEEEECCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEECCCCCE
LEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIGVVSVVEGADETLAKQVS
EHHHHHHHHHHHCCHHHHHHEEEEECCCHHHCCCEECCCCCEEEEEEECCCHHHHHHHHH
MHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTE
HHHEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKT
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCHH
VEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKAGL
HHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471