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The map label for this gene is pgsA

Identifier: 15673952

GI number: 15673952

Start: 2046241

End: 2046813

Strand: Reverse

Name: pgsA

Synonym: L29672

Alternate gene names: 15673952

Gene position: 2046813-2046241 (Counterclockwise)

Preceding gene: 15673953

Following gene: 15673951

Centisome position: 86.52

GC content: 38.05

Gene sequence:

>573_bases
ATGAAAGAGAAAATACCCAATCAATTGACAATGGCAAGGATTTTTATGATTCCAATCTTTGTGATTTTATTTTATTTACC
AGAAGGTGCACATTTTAACGGTTTTGTTTCACAAGACCATAGTTCAGTGATGTGGGTTATCGCAGCAATTGTATTTGCCG
TAGCCTCATTTACTGACTGGCTTGATGGATATCTCGCCCGTAAATGGCACGTTGTCAGCAATTTTGGTAAATTTGCTGAC
CCATTGGCCGATAAAATGCTCAATATGGTTGCCTTTGTTGTTCTAGTTGGACTTCATGTTGTTCCAATGTGGGCTGTTGC
CATTATTATTTGCCGTGAGCTTGCGGTTACAGGATTGCGCCTCTTATTGGTTGAACAAGGTGGAGTTGTTATGGCGGCTG
CAATGCCTGGTAAAATCAAAACTGCCACACAAATGTTGAGTGTTATTTTCCTTTTCATTGGAAATCCCTTGTATATAGGA
ACAATCCTCTTTTATGTTTGTGTCCTCTTTACCATTTATAGTGGCTATGACTATTTTGCTAAAAATATGCAAGTTTTTAG
AAATGCTGATTAA

Upstream 100 bases:

>100_bases
GGACCAAATAAAATTACTTTACAAATTAATCGAACGACAAGCAATTCAGCTGCTCAATAAATAAAAGCTGAGGCTTATTT
TAAGTTGCAAAAGGAGAACT

Downstream 100 bases:

>100_bases
TCATTTCCAAATAGAAAATAAAAAAATCCAAGTAGAAATACTTGGATTTTTTGTTTTGATTAGTCAAAGAAAAAAGTACC
CTAGAGGATACGAATTGAAA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKEKIPNQLTMARIFMIPIFVILFYLPEGAHFNGFVSQDHSSVMWVIAAIVFAVASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVLFTIYSGYDYFAKNMQVFRNAD

Sequences:

>Translated_190_residues
MKEKIPNQLTMARIFMIPIFVILFYLPEGAHFNGFVSQDHSSVMWVIAAIVFAVASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVLFTIYSGYDYFAKNMQVFRNAD
>Mature_190_residues
MKEKIPNQLTMARIFMIPIFVILFYLPEGAHFNGFVSQDHSSVMWVIAAIVFAVASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVLFTIYSGYDYFAKNMQVFRNAD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=187, Percent_Identity=35.8288770053476, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21299; Mature: 21299

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIPNQLTMARIFMIPIFVILFYLPEGAHFNGFVSQDHSSVMWVIAAIVFAVASFTDW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGYLARKWHVVSNFGKFADPLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIGTILFYVCVLFTIYSGYDYFA
HEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
KNMQVFRNAD
HHHHHHHCCC
>Mature Secondary Structure
MKEKIPNQLTMARIFMIPIFVILFYLPEGAHFNGFVSQDHSSVMWVIAAIVFAVASFTDW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGYLARKWHVVSNFGKFADPLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIGTILFYVCVLFTIYSGYDYFA
HEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
KNMQVFRNAD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA