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The map label for this gene is arb

Identifier: 15673653

GI number: 15673653

Start: 1721677

End: 1723110

Strand: Reverse

Name: arb

Synonym: L121426

Alternate gene names: 15673653

Gene position: 1723110-1721677 (Counterclockwise)

Preceding gene: 15673654

Following gene: 15673652

Centisome position: 72.84

GC content: 37.17

Gene sequence:

>1434_bases
ATGCCATTTAGTAAAGATTTTCTCTGGGGCGGAGCAACTGCAGCTAATCAATGTGAAGGCGGCTATAATCAGGGAGGACG
GGGGCTTGCCAATGTCGACCTTGTTCCACACGGAAAAGACCGTTTTCCAATTATTACAGGGGAAATGAAGCACCTTGAAT
TCGATGAAGAGCATTTTTATCCAGCAAAAGAAGCGATTGATATGTATCATCATTGGAAAGAAGACCTCGCACTTTTTGCT
GAAATGGGATTTAAAACCTATCGAATGTCTATTGCTTGGACAAGAATTTTTCCAAAAGGCGACGAACAAGAGCCAAATGA
AGAAGGCTTGCAATTTTATGAAGATATTTTTAGAGAATGCCAACGTTTAGGAATTGAACCCTTAGTAACCATCACTCACT
TTGATTGTCCTGTCCACCTAATTAAAGAATACGGTGGCTGGCGTAATCGAAAAATGGTTGGTTTCTATGAAAATTTAGCC
AGAGCAATTTTTACTCGTTATAAAGGATTAGTTCGCTATTGGTTGACATTTAATGAAATTAATATGCTCCTCCATGCTCC
ATTTATGGGAGCAGGACTTGTTTTTGAAGAAGGAGAAAATAAAGAACAAGCCAAATACTTAGCCGCTCATCATGAACTAT
TAGCATCGGCTTTAGCAACAAAAATTGGACATGAAGTTGACCCAGAAAATAAGATAGGCTGCATGTTAGCTGCTGGAGAT
TACTATCCATTTGATTGTAATCCAGAAAATGTTTTTGAAGCTCAAAAACAAAATCATGATAATCTCTTTTTCATTGATGT
TCAATCTCGTGGAAAATATCCAAACTACCTTTTAAAGAGATTAGAGCGTGAAGAAATTACACTTCCGATTGAAAAAGGCG
ACTTAGAAATCCTTGCTGAAAACACAGTTGACTTTATTTCATTTAGTTACTATGCAAGTCGAGTCGCTAAAGTCAAGGAT
GAGGATGCAGATAAATCAGCTGGAAATATCTTTGAATCTGTAAAAAATCCTTATTTAGAGGCCAGTGAATGGGGTTGGCA
AATTGACCCACTTGGTTTAAGAATCACAATGAATTCTATTTATGACCGCTATCAAAAACCATTATTTATTGTAGAAAATG
GTTTAGGAGCAGTAGATAAACCTGATGAAAATGGATTTGTAGCTGATGATTATCGAATTGATTACATGGCTGCACACATC
AAAGAAATGAAGAAAGCAGTTGAACTTGATGGCGTTGAACTATTAGGTTATACTTCTTGGGGATGTATTGACTTAGTATC
AGCAGGAACGGGTGAGATGAGCAAACGTTATGGATTCATCTATGTCGACCGAGACGATTATGGTAAAGGAAGTTTGAAAC
GGACGCCTAAGAAATCATTTAACTGGTACAAGAAAGTTATTGCAAGCAACGGTGAAGATTTAACAAATGAATAA

Upstream 100 bases:

>100_bases
AATTATAGAAAACGCTTCAAAAAATAGATGAGATCGCTATCAAATGTCATAAAAAAATGTTAAAATGAAAAAAAGAATAA
AAAAAGGAGTGTCATCTATT

Downstream 100 bases:

>100_bases
TTAAAAAGGGGGGCTTTCCTCCTTTTTTTATCAAACAAAACATTTCTTTGATTTAAGATTTTTATCTAGCAAGAAAAATT
TACAATAGTTAAGCAAGTGT

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKEDLALFA
EMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFRECQRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYENLA
RAIFTRYKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIGHEVDPENKIGCMLAAGD
YYPFDCNPENVFEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREEITLPIEKGDLEILAENTVDFISFSYYASRVAKVKD
EDADKSAGNIFESVKNPYLEASEWGWQIDPLGLRITMNSIYDRYQKPLFIVENGLGAVDKPDENGFVADDYRIDYMAAHI
KEMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDYGKGSLKRTPKKSFNWYKKVIASNGEDLTNE

Sequences:

>Translated_477_residues
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKEDLALFA
EMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFRECQRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYENLA
RAIFTRYKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIGHEVDPENKIGCMLAAGD
YYPFDCNPENVFEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREEITLPIEKGDLEILAENTVDFISFSYYASRVAKVKD
EDADKSAGNIFESVKNPYLEASEWGWQIDPLGLRITMNSIYDRYQKPLFIVENGLGAVDKPDENGFVADDYRIDYMAAHI
KEMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDYGKGSLKRTPKKSFNWYKKVIASNGEDLTNE
>Mature_476_residues
PFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKEDLALFAE
MGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFRECQRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYENLAR
AIFTRYKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIGHEVDPENKIGCMLAAGDY
YPFDCNPENVFEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREEITLPIEKGDLEILAENTVDFISFSYYASRVAKVKDE
DADKSAGNIFESVKNPYLEASEWGWQIDPLGLRITMNSIYDRYQKPLFIVENGLGAVDKPDENGFVADDYRIDYMAAHIK
EMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDYGKGSLKRTPKKSFNWYKKVIASNGEDLTNE

Specific function: Can hydrolyze salicin, cellobiose, and probably arbutin [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=491, Percent_Identity=28.3095723014257, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI110681710, Length=500, Percent_Identity=28, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI13273313, Length=494, Percent_Identity=27.1255060728745, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=27.9835390946502, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI28376633, Length=488, Percent_Identity=26.844262295082, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1789070, Length=472, Percent_Identity=60.5932203389831, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI2367174, Length=481, Percent_Identity=53.4303534303534, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI2367270, Length=473, Percent_Identity=52.6427061310782, Blast_Score=499, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17552856, Length=489, Percent_Identity=29.038854805726, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=28.8934426229508, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21356577, Length=502, Percent_Identity=25.2988047808765, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54772; Mature: 54641

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFY
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHCCCCCHHHCC
PAKEAIDMYHHWKEDLALFAEMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFREC
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
QRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYENLARAIFTRYKGLVRYWLTFNEI
HHCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIGHEVDPENKIGCMLAAGD
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
YYPFDCNPENVFEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREEITLPIEKGDLEILAE
CCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCEEEEEC
NTVDFISFSYYASRVAKVKDEDADKSAGNIFESVKNPYLEASEWGWQIDPLGLRITMNSI
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHCCCCEECCCEEEEEHHHH
YDRYQKPLFIVENGLGAVDKPDENGFVADDYRIDYMAAHIKEMKKAVELDGVELLGYTSW
HHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
GCIDLVSAGTGEMSKRYGFIYVDRDDYGKGSLKRTPKKSFNWYKKVIASNGEDLTNE
CHHHHHCCCCCCHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFY
CCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHCCCCCHHHCC
PAKEAIDMYHHWKEDLALFAEMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFREC
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
QRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYENLARAIFTRYKGLVRYWLTFNEI
HHCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIGHEVDPENKIGCMLAAGD
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
YYPFDCNPENVFEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREEITLPIEKGDLEILAE
CCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCEEEEEC
NTVDFISFSYYASRVAKVKDEDADKSAGNIFESVKNPYLEASEWGWQIDPLGLRITMNSI
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHCCCCEECCCEEEEEHHHH
YDRYQKPLFIVENGLGAVDKPDENGFVADDYRIDYMAAHIKEMKKAVELDGVELLGYTSW
HHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
GCIDLVSAGTGEMSKRYGFIYVDRDDYGKGSLKRTPKKSFNWYKKVIASNGEDLTNE
CHHHHHCCCCCCHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1630307; 9278503 [H]