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The map label for this gene is ccpA

Identifier: 15673630

GI number: 15673630

Start: 1695930

End: 1696928

Strand: Reverse

Name: ccpA

Synonym: L0143

Alternate gene names: 15673630

Gene position: 1696928-1695930 (Counterclockwise)

Preceding gene: 15673632

Following gene: 15673629

Centisome position: 71.73

GC content: 36.44

Gene sequence:

>999_bases
ATGGTAGAATCAACAACAACAATTTATGATGTGGCACGTGTCGCCGGAGTGTCAATGGCAACCGTTAGTCGTGTTGTAAA
TGGAAATGCAAATGTAAAGGAAAAGACGCGCCAGAAGGTCTTAGAAGCTATTGCTGAGCTTGACTATCGTCCTAATGCAG
TTGCGCGCGGACTCGCAAGTAAACGTACAACAACAGTTGGTGTTATCTTGCCAACCATCACTTCAACTTACTTCGCAGCG
ATTACTCGCGGGGTTGATGATATCGATTCCATGTATAAATACAACATGATTTTAGCTAATAGTGATAATGATGTTGAAAA
AGAAGAAAAAGTTTTAGAAACTTTCTTATCAAAACAAGTTGACGGAATCGTCTATATGGGTTCATCTTTAGATGAAAAAA
TTAGAACTTCCCTCAAAAATTCAAGAACACCTGTCGTTTTAGTTGGAACAATCGATGGAGATAAAGAAATTCCATCTGTT
AATATTGATTACCATTTGGCTGCTTATCAATCAACTAAAAAATTGATTGATAGCGGAAATAAAAAAATCGCTTATATCAT
GGGTTCATTGAAAGACGTTGAAAATACAGAACGCATGGTTGGTTATCAAGAAGCTTTGCTTGAAGCAAATATTGAATTTG
ATGAAAACCTCGTTTTTGAAGGTAATTATAGCTATGAACAAGGAAAAGCACTTGCTGAACGTTTACTTGAGCGAGGAGCA
ACTTCTGCAGTAGTATCACATGATACAGTAGCCGTTGGACTCTTGTCTGCAATGATGGATAAAGGAGTGAAAGTTCCTGA
AGATTTCGAAATTATCTCAGGTGCAAATTCACCAATTACTCAATATACATATCCAACTTTAACTTCTGTTAACCAACCCC
TTTACGATTTGGGAGCAGTAGCAATGCGTCTTTTGACAAAATTAATGCTTAAAGAAGATGTTGAACAAAATCAATTAGTT
TTGGATCATGAAATTTTTTCTCGTCGTTCTACCAAATAA

Upstream 100 bases:

>100_bases
CTGAAGGTTGAAAAGGTTTACAGTTAATGATATAATTTGTAAATAAAAATGGTTTTCATAAATACTATGAATAAAAAGAA
AAGAAAGAGGATAGCCAATT

Downstream 100 bases:

>100_bases
AAATCAAGCCCTTTTGAGGGCTTTTTTTATTTAAAGTAAAAAGTATTTGACATTTGAGAGAAAAGTCGCAATAATAGAGA
GATGATAAAAAGAATTTATT

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTKKLIDSGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLERGA
TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIFSRRSTK

Sequences:

>Translated_332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTKKLIDSGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLERGA
TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIFSRRSTK
>Mature_332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTKKLIDSGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLERGA
TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIFSRRSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=31.3253012048193, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=31.0030395136778, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=31.3333333333333, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788474, Length=300, Percent_Identity=31, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=29.483282674772, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=29.6636085626911, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=30.4794520547945, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=28.7425149700599, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790715, Length=338, Percent_Identity=26.0355029585799, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=29.1139240506329, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=27.4390243902439, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786268, Length=310, Percent_Identity=25.4838709677419, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789456, Length=295, Percent_Identity=26.1016949152542, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790689, Length=319, Percent_Identity=21.3166144200627, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36647; Mature: 36647

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRTTTVGVILPTITSTYFAAITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQV
CCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHC
DGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTKKLIDSGN
CCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
KKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLERGA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHH
AMRLLTKLMLKEDVEQNQLVLDHEIFSRRSTK
HHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCC
>Mature Secondary Structure
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRTTTVGVILPTITSTYFAAITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQV
CCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHC
DGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTKKLIDSGN
CCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
KKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKALAERLLERGA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
TSAVVSHDTVAVGLLSAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHH
AMRLLTKLMLKEDVEQNQLVLDHEIFSRRSTK
HHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]