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The map label for this gene is rbsK

Identifier: 15673621

GI number: 15673621

Start: 1686409

End: 1687311

Strand: Reverse

Name: rbsK

Synonym: L86157

Alternate gene names: 15673621

Gene position: 1687311-1686409 (Counterclockwise)

Preceding gene: 15673622

Following gene: 15673620

Centisome position: 71.33

GC content: 36.1

Gene sequence:

>903_bases
ATGACAAAAGTAAGTGTTATAGGAAGTATTTCAATGGATTTAGTCACAAGGACTAACCGAGTGCCGAATGCTGGAGAAAC
AGTATTTGGTGAAGATTTCGCTATGGTTCCCGGTGGAAAAGGAGCGAACCAAGCCGTTGCTTTTGCCAGACTTTCTCCCA
ATGAAGTAAGTATGATTGGAGCAGTAGGCAAGGATGCTTTTGGTGAGAGTATTTTGCAAAACTTCAAAGAAAATGCAGTT
CTTTTTGAAAATGTGGGAACGGTACCACAAACAACAGGAATTGCTCAAATTACTCTCTATGATGACGATAATCGTATTAT
TATTATTCCAGGTGCTAATAATGAAGTTCTACCAAGTTATCTAGCAGACCTTTGGGAGAAAATTAAAGAAAGCCAACTTG
TTATTCTACAAAATGAAATTCCACATGAAACAAATCTAGCGATTGCTAAATTCTGTAAAGAAAATGCGATAAAAGTTCTT
TATAATCCAGCTCCAGCAAGAAAAACAGATTTGGAAATGATTGATTTTGTTGATTATATCACACCGAATGAACACGAATG
TAAGGAACTTTTTCCAAATTTAGCACTTGAAGAAATTCTCAAAAAATATTCAAATCGTCTGATTGTCACCTTAGGAAGTG
AAGGAGTCATTTTCCACGATGGAGAGACTCTTCAAAAAATTCCTGCCATAAAAGCTAAAGTTGTAGATACAACTGGTGCA
GGAGATACATTCAACGGAGCCTTTGCCTTTGGTTTGACTGAGAACTTATCAATTAGTGATTCTATCAGATTAGCTGTCGT
TGCTTCTCATTTATCTATTCAAAAATTTGGCGCACAAGGCGGGATGCCAAAGCTATCAGAAGTTAAAGCAAAATTAAAAG
AACTTGAAATTAATCTCTACTAA

Upstream 100 bases:

>100_bases
GCGACTGATCAAGCAATTGAGAAGTCTAAAATTGAACTCCCTGTTCATTATGTAGCGCGTGAAACAATTCGACAAAAGAG
AAAAGAATGAGGAAAAATTA

Downstream 100 bases:

>100_bases
AAAAGAAAGAGAGTTAAATTTATGAAAAAAGAAGGAATACTTAATAGTGAATTAGCAAAAATTGCTGACGATTTGGGCCA
TACTGACCAAGTTTGTATTG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTKVSVIGSISMDLVTRTNRVPNAGETVFGEDFAMVPGGKGANQAVAFARLSPNEVSMIGAVGKDAFGESILQNFKENAV
LFENVGTVPQTTGIAQITLYDDDNRIIIIPGANNEVLPSYLADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVL
YNPAPARKTDLEMIDFVDYITPNEHECKELFPNLALEEILKKYSNRLIVTLGSEGVIFHDGETLQKIPAIKAKVVDTTGA
GDTFNGAFAFGLTENLSISDSIRLAVVASHLSIQKFGAQGGMPKLSEVKAKLKELEINLY

Sequences:

>Translated_300_residues
MTKVSVIGSISMDLVTRTNRVPNAGETVFGEDFAMVPGGKGANQAVAFARLSPNEVSMIGAVGKDAFGESILQNFKENAV
LFENVGTVPQTTGIAQITLYDDDNRIIIIPGANNEVLPSYLADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVL
YNPAPARKTDLEMIDFVDYITPNEHECKELFPNLALEEILKKYSNRLIVTLGSEGVIFHDGETLQKIPAIKAKVVDTTGA
GDTFNGAFAFGLTENLSISDSIRLAVVASHLSIQKFGAQGGMPKLSEVKAKLKELEINLY
>Mature_299_residues
TKVSVIGSISMDLVTRTNRVPNAGETVFGEDFAMVPGGKGANQAVAFARLSPNEVSMIGAVGKDAFGESILQNFKENAVL
FENVGTVPQTTGIAQITLYDDDNRIIIIPGANNEVLPSYLADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVLY
NPAPARKTDLEMIDFVDYITPNEHECKELFPNLALEEILKKYSNRLIVTLGSEGVIFHDGETLQKIPAIKAKVVDTTGAG
DTFNGAFAFGLTENLSISDSIRLAVVASHLSIQKFGAQGGMPKLSEVKAKLKELEINLY

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=36.1774744027304, Blast_Score=142, Evalue=5e-34,
Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=34.5637583892617, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082343, Length=297, Percent_Identity=26.2626262626263, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081971, Length=282, Percent_Identity=23.0496453900709, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=37.012987012987, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=35.4545454545455, Blast_Score=156, Evalue=5e-39,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=32.8990228013029, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24583886, Length=315, Percent_Identity=23.4920634920635, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RBSK_LACLA (Q9CF42)

Other databases:

- EMBL:   AE005176
- PIR:   G86829
- RefSeq:   NP_267795.1
- ProteinModelPortal:   Q9CF42
- SMR:   Q9CF42
- GeneID:   1115299
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L86157
- NMPDR:   fig|272623.1.peg.1681
- HOGENOM:   HBG697973
- OMA:   NEHECKE
- ProtClustDB:   CLSK697853
- BioCyc:   LLAC272623:L86157-MONOMER
- BRENDA:   2.7.1.15
- GO:   GO:0005737
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139
- PRINTS:   PR00990
- TIGRFAMs:   TIGR02152

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.15

Molecular weight: Translated: 32656; Mature: 32525

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVSVIGSISMDLVTRTNRVPNAGETVFGEDFAMVPGGKGANQAVAFARLSPNEVSMIG
CCEEEEEECCHHHHHHHCCCCCCCCCEEECCCEEECCCCCCCCCEEEEEECCCCCEEEEE
AVGKDAFGESILQNFKENAVLFENVGTVPQTTGIAQITLYDDDNRIIIIPGANNEVLPSY
CCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHH
LADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVLYNPAPARKTDLEMIDFVDYI
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHC
TPNEHECKELFPNLALEEILKKYSNRLIVTLGSEGVIFHDGETLQKIPAIKAKVVDTTGA
CCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCEEEEEECCCC
GDTFNGAFAFGLTENLSISDSIRLAVVASHLSIQKFGAQGGMPKLSEVKAKLKELEINLY
CCCCCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECC
>Mature Secondary Structure 
TKVSVIGSISMDLVTRTNRVPNAGETVFGEDFAMVPGGKGANQAVAFARLSPNEVSMIG
CEEEEEECCHHHHHHHCCCCCCCCCEEECCCEEECCCCCCCCCEEEEEECCCCCEEEEE
AVGKDAFGESILQNFKENAVLFENVGTVPQTTGIAQITLYDDDNRIIIIPGANNEVLPSY
CCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHH
LADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVLYNPAPARKTDLEMIDFVDYI
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHC
TPNEHECKELFPNLALEEILKKYSNRLIVTLGSEGVIFHDGETLQKIPAIKAKVVDTTGA
CCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCEEEEEECCCC
GDTFNGAFAFGLTENLSISDSIRLAVVASHLSIQKFGAQGGMPKLSEVKAKLKELEINLY
CCCCCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471