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The map label for this gene is tkt

Identifier: 15673607

GI number: 15673607

Start: 1669206

End: 1671182

Strand: Reverse

Name: tkt

Synonym: L0043

Alternate gene names: 15673607

Gene position: 1671182-1669206 (Counterclockwise)

Preceding gene: 15673608

Following gene: 15673606

Centisome position: 70.65

GC content: 40.06

Gene sequence:

>1977_bases
ATGTTTGATACTACTGATCAATTGGCTGTAAATACGATTCGTACTCTATCATTAGATGCGATTCAAAAAGCAAATTCAGG
ACATCCTGGACTTCCAATGGGCTCTGCACCAATGGCTTATGTACTTTGGAGCAAATTTCTTAATGTGAACCCTAAGACAA
GTCGTAAATGGTCAAATCGTGACCGTTTTGTCTTGTCTGCTGGTCATGGTTCTGCAATGTTATATAGTTTATTACATTTG
GCAGGTTATAATGTAACGACTGATGATTTAAAAGGTTTCCGTCAATGGCAATCAAAAACACCGGGACATCCAGAAGTTAA
TCATACAGATGGTGTTGAAGCAACAACAGGTCCTTTAGGACAAGGAATTGCCAATGCTGTCGGAATGGCAATGGCTGAAG
CACATTTAGCAGCACAATACAATAAACCTGGTTTTGATATTGTTGACCATTACACTTACGCCTTAAATGGTGATGGTGAT
TTGATGGAAGGTGTTTCACAAGAAGCAGCTTCACTTGCAGGTAAATTGAAACTTGGTAAATTGATTCTTTTCTATGATTC
AAATAATATTTCTCTAGATGGTGACTTATCTATGTCATTTATTGATGATATTCAAAAACGTTTTGAATCATATGGCTGGC
AACATTTATTGGTAAAAGATGGAAATGATTTAGAAGAAATCGCAGCAGCTGTTGAAGTGGCTAAAGCTGAAAAATCTAAA
CCAACAATCATTGAAGTTAAAACAGTCATTGGTTTTGGTGCTGAAAAACAAGGAACTTCAGCAGTTCACGGAGCTCCTCT
TGGAGCTGAAGGTGTTGCATTTGCCAAGAAAGCATATGGTTGGGATTATCCTGAATTTACAGTTCCTGAAGAAGTATCAA
AACGCTTTTTAGAAACGACAGTTGCGCGTGGTGAAGCGATGGAGCAAGTATGGCGCAGTACTTTTGATGATTATTCTGAA
AAATACCCTGAGCTTGCTGAGCAATACGCAAAAGCTTTTGAAAATGAAACGCCAGAGCTTACTTTGACCAAGCATGAAAT
GGAAACAAGCAAGGCCAGCCGTGTAACTTCACAAGAAGCTATCCAAGAATTATCAGCTCAAATGCCAAATCTTTGGGGTG
GGTCTGCTGACCTTTCGGCTTCAAATAATACAATGGTTAAAGTTGAAGAAGACTTCATGCCAGATAACTATGCTGGACGT
AATATTTGGTTTGGTGTACGTGAATTTGCAATGGGAGCCATTATGAATGGGATTGCTTTGCATGGTGGAACTCGTGTCTA
TGGCGGAACATTCTTCGTCTTCTCAAACTACATGCTTCCTTCTGTTCGGATGGCTGCTCTACAAAGCTTACCAGTTACTT
ATGTTTGGACACATGATTCCATTGCTGTTGGGGAAGATGGTCCAACTCACGAACCTGTTGAACAATTAGCTTCTGTTCGC
TCAATTCCTAATTTGGATGTAATTCGTCCAGCTGATGGAAATGAAGTAGTGGCTGCATGGCGTCGTGCTGCATCAAGTAA
AAGCCGCCCAACCGCACTTATTTTGACTCGTCAAAATCTTCCAGTTTTACCTGATACTTATGAATTGGCTGAAGAAGGTC
TGAATCGTGGGGCTTATATTCTTTCAAAAGAAGAAGGAAAACTTGAAGGAATCATCATTGCGACTGGTTCAGAAGTAGCA
TTAGCTCTTGAAGCTAAGAAGACTTTGGGTTCTGGCATTCGTGTCGTTTCAATGCCTTCAATGAATATTTTTGACGAACA
AGAAGCAGCTTATCGCGAAGAAATTTTACCAAAAGATGTAAGACGTCGTTTAGCGATTGAAGCTGGTACAAGTTACGGAT
GGGGTAAATATGTTGGACTTGATGGTGCAACAGTTACAGTAGATACTTGGGGCGCTTCGGCACCAGCAAATATCGTTCTT
CCAGCTTACGGATTTACTGCTGAAAATGTAGTTAAAGCATACAAAGAGCTTGACTAA

Upstream 100 bases:

>100_bases
AAAAACATAAAAAAAGAAAAAAATTTTAATTTCAGAGAATGAAAACCGTTTCTAACTTGTGTTATAATGTGAGTATAAAT
AAAAAATATGGAGAAATCTT

Downstream 100 bases:

>100_bases
TATTGAAAAAGGAGTTCTGATTTTTTGTCAGAGCTCTTTTGATTACAAACAAGTCTGTCAGTAAATTTTAATTAAAAAAT
AGAAAGGAAATAAGATGGGG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRSTFDDYSE
KYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVVKAYKELD

Sequences:

>Translated_658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRSTFDDYSE
KYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVVKAYKELD
>Mature_658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRSTFDDYSE
KYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVVKAYKELD

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=524, Percent_Identity=26.9083969465649, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI4507521, Length=524, Percent_Identity=26.9083969465649, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI133778974, Length=528, Percent_Identity=26.7045454545455, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI225637463, Length=421, Percent_Identity=23.9904988123515, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI225637459, Length=421, Percent_Identity=23.9904988123515, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI225637461, Length=421, Percent_Identity=23.9904988123515, Blast_Score=98, Evalue=3e-20,
Organism=Escherichia coli, GI48994911, Length=660, Percent_Identity=51.0606060606061, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1788808, Length=660, Percent_Identity=49.3939393939394, Blast_Score=603, Evalue=1e-174,
Organism=Caenorhabditis elegans, GI17539652, Length=662, Percent_Identity=25.0755287009063, Blast_Score=145, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6325331, Length=667, Percent_Identity=48.2758620689655, Blast_Score=587, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6319593, Length=666, Percent_Identity=46.6966966966967, Blast_Score=555, Evalue=1e-159,
Organism=Drosophila melanogaster, GI45551847, Length=677, Percent_Identity=25.7016248153619, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI45550715, Length=677, Percent_Identity=25.7016248153619, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24666278, Length=508, Percent_Identity=27.3622047244095, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24645119, Length=649, Percent_Identity=25.4237288135593, Blast_Score=141, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71726; Mature: 71726

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DRFVLSAGHGSAMLYSLLHLAGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLG
CCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGDLMEGVSQEAASLAGKLKLGK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEECCCCHHHHHHHHHHHHHHCCEEECE
LILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
EEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETT
CCEEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VARGEAMEQVWRSTFDDYSEKYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
IQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGRNIWFGVREFAMGAIMNGIAL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
HGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
CCCCEEECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHH
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYI
CCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LSKEEGKLEGIIIATGSEVALALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDV
EECCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCHHH
RRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVLPAYGFTAENVVKAYKELD
HHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DRFVLSAGHGSAMLYSLLHLAGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLG
CCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGDLMEGVSQEAASLAGKLKLGK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEECCCCHHHHHHHHHHHHHHCCEEECE
LILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
EEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETT
CCEEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VARGEAMEQVWRSTFDDYSEKYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
IQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGRNIWFGVREFAMGAIMNGIAL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
HGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
CCCCEEECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHH
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYI
CCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LSKEEGKLEGIIIATGSEVALALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDV
EECCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCHHH
RRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVLPAYGFTAENVVKAYKELD
HHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA