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The map label for this gene is yqgE

Identifier: 15673605

GI number: 15673605

Start: 1667622

End: 1668485

Strand: Reverse

Name: yqgE

Synonym: L67370

Alternate gene names: 15673605

Gene position: 1668485-1667622 (Counterclockwise)

Preceding gene: 15673606

Following gene: 15673604

Centisome position: 70.53

GC content: 39.93

Gene sequence:

>864_bases
ATGGATGTTTCATGGATGACAAAATATATTGCTGAGGGATTGGGAACTATGCTTCTCGTCTTGCTTGGTAATGGTACAAT
TGCTGGGGTAACCCTCAAAGGCTCTAAAAATGAGGGCATGGGTGGTCTTGCAATTGCGTGGGGATACGGAATTGCGATTT
TAGTTCCTGTACTTGCTTTTGCAAATGTTTCAGGTGCACATATTAATCCAGCAATTACAATTGGACTCGCTTCAGCTGGC
TATTTCCCTTGGGCACATGTTGCACAATATATTTTGGCACAACTTATTGGTGCAATTATTGGTCAATTACTTGTTGTAGC
GATTTATAAAGAATACTTCGCTAAAACTAATGACGGAGCAATTTCTTTAGGCGCTTTTTCAACAACTAACGCTTTGGATA
ATGGTTCAAATCGTGGAAAAGCAATTTTCAACGGATTTATCAATGAAGTAATCGGAATGTTTGTATTTGTTTTCGGAATT
CTCAGTTTTACAACGAACTTCTTTGGTGCAGAATCAATCAAATGGATGACAAGCTACGCTCAACAACAAGGAGCTGATGT
TACAGCGAATGCAACAGTAAGCCAAATTTGGGCTTCTGTTTCAGGCGCTTCATCATCTAAAATGATTGGTGCGCTTGCTA
TTGGTTTAATGTTTGTTGGTTTGGTTACAGCATTTGGTGGACCAACTGGTGCAGCATTGAATCCAGCACGTGACCTTGGT
CCTCGTATCGTTTATAGCTTCTTACCACAATCAGTTGTTGGTGAAAATAAAGACGCTAAATGGTGGTACGCTTGGGTTCC
AGTTGTTGCCACAATCGTTGGTGCAGTAATTGCAGCTACAGTCTTTAAACTTATGTTTAAATAA

Upstream 100 bases:

>100_bases
TCATATTTTCGATGTTATTATTAGCAAGAGTTAAGAAAAATATGATAAAATTGAAGTGTCAACATCTTTATATATTTTTC
AAAATAGAAAGGAAATTATC

Downstream 100 bases:

>100_bases
AAACAAAAATTTCTGTCGAAAGGCAGATTTTTTCTTGCCCTTATAACTTAAAAGCGCTATAATAATTATAATTTACTGAA
AAGGACAGACAATTATGACA

Product: transporter

Products: glycerol [Cytoplasm] [C]

Alternate protein names: Aquaglyceroporin; Glyceroaquaporin [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MDVSWMTKYIAEGLGTMLLVLLGNGTIAGVTLKGSKNEGMGGLAIAWGYGIAILVPVLAFANVSGAHINPAITIGLASAG
YFPWAHVAQYILAQLIGAIIGQLLVVAIYKEYFAKTNDGAISLGAFSTTNALDNGSNRGKAIFNGFINEVIGMFVFVFGI
LSFTTNFFGAESIKWMTSYAQQQGADVTANATVSQIWASVSGASSSKMIGALAIGLMFVGLVTAFGGPTGAALNPARDLG
PRIVYSFLPQSVVGENKDAKWWYAWVPVVATIVGAVIAATVFKLMFK

Sequences:

>Translated_287_residues
MDVSWMTKYIAEGLGTMLLVLLGNGTIAGVTLKGSKNEGMGGLAIAWGYGIAILVPVLAFANVSGAHINPAITIGLASAG
YFPWAHVAQYILAQLIGAIIGQLLVVAIYKEYFAKTNDGAISLGAFSTTNALDNGSNRGKAIFNGFINEVIGMFVFVFGI
LSFTTNFFGAESIKWMTSYAQQQGADVTANATVSQIWASVSGASSSKMIGALAIGLMFVGLVTAFGGPTGAALNPARDLG
PRIVYSFLPQSVVGENKDAKWWYAWVPVVATIVGAVIAATVFKLMFK
>Mature_287_residues
MDVSWMTKYIAEGLGTMLLVLLGNGTIAGVTLKGSKNEGMGGLAIAWGYGIAILVPVLAFANVSGAHINPAITIGLASAG
YFPWAHVAQYILAQLIGAIIGQLLVVAIYKEYFAKTNDGAISLGAFSTTNALDNGSNRGKAIFNGFINEVIGMFVFVFGI
LSFTTNFFGAESIKWMTSYAQQQGADVTANATVSQIWASVSGASSSKMIGALAIGLMFVGLVTAFGGPTGAALNPARDLG
PRIVYSFLPQSVVGENKDAKWWYAWVPVVATIVGAVIAATVFKLMFK

Specific function: Mixed channel protein that transports both water and glycerol [H]

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4826645, Length=289, Percent_Identity=26.643598615917, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI22538420, Length=283, Percent_Identity=25.0883392226148, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI157266307, Length=287, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1790362, Length=276, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787101, Length=134, Percent_Identity=34.3283582089552, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558372, Length=291, Percent_Identity=27.4914089347079, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533613, Length=269, Percent_Identity=27.8810408921933, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32564052, Length=269, Percent_Identity=27.8810408921933, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993722, Length=286, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531431, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17531429, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321054, Length=263, Percent_Identity=28.8973384030418, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 30053; Mature: 30053

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSWMTKYIAEGLGTMLLVLLGNGTIAGVTLKGSKNEGMGGLAIAWGYGIAILVPVLAF
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ANVSGAHINPAITIGLASAGYFPWAHVAQYILAQLIGAIIGQLLVVAIYKEYFAKTNDGA
HCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ISLGAFSTTNALDNGSNRGKAIFNGFINEVIGMFVFVFGILSFTTNFFGAESIKWMTSYA
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QQQGADVTANATVSQIWASVSGASSSKMIGALAIGLMFVGLVTAFGGPTGAALNPARDLG
HHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
PRIVYSFLPQSVVGENKDAKWWYAWVPVVATIVGAVIAATVFKLMFK
HHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVSWMTKYIAEGLGTMLLVLLGNGTIAGVTLKGSKNEGMGGLAIAWGYGIAILVPVLAF
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ANVSGAHINPAITIGLASAGYFPWAHVAQYILAQLIGAIIGQLLVVAIYKEYFAKTNDGA
HCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ISLGAFSTTNALDNGSNRGKAIFNGFINEVIGMFVFVFGILSFTTNFFGAESIKWMTSYA
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QQQGADVTANATVSQIWASVSGASSSKMIGALAIGLMFVGLVTAFGGPTGAALNPARDLG
HHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
PRIVYSFLPQSVVGENKDAKWWYAWVPVVATIVGAVIAATVFKLMFK
HHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glycerol [Periplasm] [C]

Specific reaction: glycerol [Periplasm] = glycerol [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]