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The map label for this gene is asd

Identifier: 15673604

GI number: 15673604

Start: 1666451

End: 1667527

Strand: Reverse

Name: asd

Synonym: L66199

Alternate gene names: 15673604

Gene position: 1667527-1666451 (Counterclockwise)

Preceding gene: 15673605

Following gene: 15673603

Centisome position: 70.49

GC content: 39.18

Gene sequence:

>1077_bases
ATGACACAATATAATATCGCCGTCGTTGGTGTTACTGGTGCCGTGGGTACACGTATGCTTGAACAATTAGAAGAATCTAC
ACTTCCTATAGAAACCGTACGTGCGCTTGCAAGTAAACGTTCGGCAGGAAAAATTGTTGAATTTAAGGGGCAAGAGCTTG
TTGTAGAAGAATTGACTGAGGATAGTTTTGAAAATATTGATATTGCTCTTTTTTCAGCCGGAGGCTCAGTATCAGAAAAA
TATGCCCCTTATGCTGTAAAAGCTGGAGCTGTTGTCGTAGATAACACCTCATTTTTCCGTCAAAACCCTAATGTCCCCTT
GGTTGTTCCAGAAGTTAATGCACATGCTTTGGAAAAACACAATGGAATAATTGCCTGTCCTAATTGCTCAACGATTCAAA
TGATGGTTGCTTTAGAGCCGATTCGTCAAGCTTATGGGCTTGAGCGAGTAATTGTCAGCACTTATCAAGCGGTCTCTGGT
GCGGGTCAATCAGCAATTAATGAAACAAATCGTGAACTCCAAGAAGCACTTGATGGAAAAGCACTGACAGAATTGTCAGC
AGAAATTTTACCGTCTGCTGGAGATAAAAAACATTATCCAATTGCTTACAATGCGCTTGCACAAATTGATGTATTTACTG
ACAATGATTATACTTATGAAGAAATGAAAATGACAAATGAAACCAAGAAAATCATGGAAGATGATTCAATTGCGGTTTCG
GCAACTTGTGTCAGAATTCCAGTTCTTTACGGTCATTCTGAGTCAGTTTATGTTGAAACGAAAAAAGTAGCAGATATTGC
TGAGGTTAAACGTTTGATTTCTGAATTCCCAGGAGCTGTTTTAGAAGATGATGTTGCTCATCAAATTTATCCACAAGCCA
TTAATTCAGTTGGTCGTCGTGAAACTTTTGTGGGTCGTATTCGCCGTGATTTGGATGCAGCAAATGGGATTCATCTTTGG
GTAGTTTCTGACAATTTACTCAAAGGAGCAGCTTGGAATTCTGTTCAAATTGCTGAAACGCTACATGAGCGTGGCTTAGT
TAGACCAACTCATGAGTTAAAATTTGAACTGAAATAA

Upstream 100 bases:

>100_bases
AAATAAAAACAAAAATTTCTGTCGAAAGGCAGATTTTTTCTTGCCCTTATAACTTAAAAGCGCTATAATAATTATAATTT
ACTGAAAAGGACAGACAATT

Downstream 100 bases:

>100_bases
AGTCTGTTAAATGAGTTATATCAGTAAAATTCGTGAAAAAATTGGCCATGAGCTTTTGATTTATCTGGGAGCAGGCGTTA
TTGTCTATTCTGATGAAAAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTQYNIAVVGVTGAVGTRMLEQLEESTLPIETVRALASKRSAGKIVEFKGQELVVEELTEDSFENIDIALFSAGGSVSEK
YAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEKHNGIIACPNCSTIQMMVALEPIRQAYGLERVIVSTYQAVSG
AGQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
ATCVRIPVLYGHSESVYVETKKVADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTHELKFELK

Sequences:

>Translated_358_residues
MTQYNIAVVGVTGAVGTRMLEQLEESTLPIETVRALASKRSAGKIVEFKGQELVVEELTEDSFENIDIALFSAGGSVSEK
YAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEKHNGIIACPNCSTIQMMVALEPIRQAYGLERVIVSTYQAVSG
AGQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
ATCVRIPVLYGHSESVYVETKKVADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTHELKFELK
>Mature_357_residues
TQYNIAVVGVTGAVGTRMLEQLEESTLPIETVRALASKRSAGKIVEFKGQELVVEELTEDSFENIDIALFSAGGSVSEKY
APYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEKHNGIIACPNCSTIQMMVALEPIRQAYGLERVIVSTYQAVSGA
GQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVSA
TCVRIPVLYGHSESVYVETKKVADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLWV
VSDNLLKGAAWNSVQIAETLHERGLVRPTHELKFELK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=30.4985337243402, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=24.6498599439776, Blast_Score=78, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=403, Percent_Identity=26.7990074441687, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39293; Mature: 39162

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYNIAVVGVTGAVGTRMLEQLEESTLPIETVRALASKRSAGKIVEFKGQELVVEELTE
CCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCC
DSFENIDIALFSAGGSVSEKYAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEKH
CCCCCCEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHC
NGIIACPNCSTIQMMVALEPIRQAYGLERVIVSTYQAVSGAGQSAINETNRELQEALDGK
CCEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLYGHSESVYVETKKVADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRR
EEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHH
ETFVGRIRRDLDAANGIHLWVVSDNLLKGAAWNSVQIAETLHERGLVRPTHELKFELK
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHCEEECC
>Mature Secondary Structure 
TQYNIAVVGVTGAVGTRMLEQLEESTLPIETVRALASKRSAGKIVEFKGQELVVEELTE
CCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCC
DSFENIDIALFSAGGSVSEKYAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEKH
CCCCCCEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHC
NGIIACPNCSTIQMMVALEPIRQAYGLERVIVSTYQAVSGAGQSAINETNRELQEALDGK
CCEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLYGHSESVYVETKKVADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRR
EEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHH
ETFVGRIRRDLDAANGIHLWVVSDNLLKGAAWNSVQIAETLHERGLVRPTHELKFELK
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2434499; 12397186 [H]