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The map label for this gene is yqeI

Identifier: 15673589

GI number: 15673589

Start: 1649621

End: 1650535

Strand: Direct

Name: yqeI

Synonym: L49325

Alternate gene names: 15673589

Gene position: 1649621-1650535 (Clockwise)

Preceding gene: 15673588

Following gene: 15673596

Centisome position: 69.73

GC content: 38.25

Gene sequence:

>915_bases
ATGAGCCTTAAAAATAAACAAATAAAAAGCGAGCATGACCATAATCATCTGGATAAACTTGTCTCACAAAACGTCACAAT
CGTTTTTGCTTTAAACCTCTTCTTTGCGATTTTAGAATTTATTTTTGGGGTGCTCTTTAATTCTACGGCTATTTTATCTG
ATGCCGTCCATGACACAGGAGATGCCGTTGCTATCGGTTTAGCCTGGTTTTTCCAAAAATTCTCTAAAAAACGAGAAGAC
AAACACTTCTCTTTTGGTTATCAACGTTTTAGTTTACTCGGCGCCTCACTCACAAGTGTCATTTTAATTACGGGGAGTTT
CATTGTGCTTTTCGAAGCCGTTCCTAGATTTTTCAACCCTCAACCTGTAGAAGCAACAGGTATGCTTGGTTTGGCTATTT
TTGCAATTGTCGCCAATGGTTTTGGTGCATGGCTTTTGGCTCGTGGTTCCTCACGAAATGAAAGTATTTTAAATCTCCAC
GCGCTCGAAGACGTTTTAGGTTGGCTGGGAGTCCTCATTGTTTCAATCGTCCTTCATTTTGTAAAATGGTACTGGCTCGA
CCCACTTCTTTCTATTCTAATTGCTTTGTTCATCTTATCCAAAGCCATTCCAAAATTCTGGGGAACTTTACGTATTCTTC
TTGAATCAGTCCCCGAAGATATTGATTACAAAAATCTTCTAAGAGCCCTTGAACAACTTCCTGAAGTACTTGCTGTCACA
CAACTTATCATTTGGTCAATTGACGGTGAGCAAAATGCAGCAATGATTCATATTGTGATTCCCGAAAATCAAGATTTCTC
AGATGCAAAAATCGCTGTTCGTAAGCTTTTAGAAAGTGAGAAAGTTTGTCGCTCAGCCATTGAACTTGATGAAACTACTG
ACGAACATAAAAAACATGTTCAATATGAAATTTAA

Upstream 100 bases:

>100_bases
AAAATTGGAAAAACGGTCACTTACAGTATCTATGACCGCCATATTTTACATCTTTTGAAAGATGTTGCAGAACATTTGGA
TGAACAAGAGGGAGGAAATC

Downstream 100 bases:

>100_bases
TTACTGACAGAACTTGTCAATTTATAAAATTACTGATGAATTAAAAGACTCGGCTTATAAAAAGCCGAGTCTTTTAATAT
TTTTAACGAATTTGTCCTGT

Product: cation transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLKNKQIKSEHDHNHLDKLVSQNVTIVFALNLFFAILEFIFGVLFNSTAILSDAVHDTGDAVAIGLAWFFQKFSKKRED
KHFSFGYQRFSLLGASLTSVILITGSFIVLFEAVPRFFNPQPVEATGMLGLAIFAIVANGFGAWLLARGSSRNESILNLH
ALEDVLGWLGVLIVSIVLHFVKWYWLDPLLSILIALFILSKAIPKFWGTLRILLESVPEDIDYKNLLRALEQLPEVLAVT
QLIIWSIDGEQNAAMIHIVIPENQDFSDAKIAVRKLLESEKVCRSAIELDETTDEHKKHVQYEI

Sequences:

>Translated_304_residues
MSLKNKQIKSEHDHNHLDKLVSQNVTIVFALNLFFAILEFIFGVLFNSTAILSDAVHDTGDAVAIGLAWFFQKFSKKRED
KHFSFGYQRFSLLGASLTSVILITGSFIVLFEAVPRFFNPQPVEATGMLGLAIFAIVANGFGAWLLARGSSRNESILNLH
ALEDVLGWLGVLIVSIVLHFVKWYWLDPLLSILIALFILSKAIPKFWGTLRILLESVPEDIDYKNLLRALEQLPEVLAVT
QLIIWSIDGEQNAAMIHIVIPENQDFSDAKIAVRKLLESEKVCRSAIELDETTDEHKKHVQYEI
>Mature_303_residues
SLKNKQIKSEHDHNHLDKLVSQNVTIVFALNLFFAILEFIFGVLFNSTAILSDAVHDTGDAVAIGLAWFFQKFSKKREDK
HFSFGYQRFSLLGASLTSVILITGSFIVLFEAVPRFFNPQPVEATGMLGLAIFAIVANGFGAWLLARGSSRNESILNLHA
LEDVLGWLGVLIVSIVLHFVKWYWLDPLLSILIALFILSKAIPKFWGTLRILLESVPEDIDYKNLLRALEQLPEVLAVTQ
LIIWSIDGEQNAAMIHIVIPENQDFSDAKIAVRKLLESEKVCRSAIELDETTDEHKKHVQYEI

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI21359890, Length=273, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI20070323, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI52352805, Length=260, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21361112, Length=303, Percent_Identity=26.0726072607261, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI289803013, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI289803009, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI289803007, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI289803003, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI64762489, Length=279, Percent_Identity=24.7311827956989, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI52351208, Length=127, Percent_Identity=29.1338582677165, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1786966, Length=247, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32564488, Length=303, Percent_Identity=22.7722772277228, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193210990, Length=307, Percent_Identity=26.3843648208469, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17555794, Length=321, Percent_Identity=23.98753894081, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17555796, Length=301, Percent_Identity=24.2524916943522, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34259; Mature: 34128

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKNKQIKSEHDHNHLDKLVSQNVTIVFALNLFFAILEFIFGVLFNSTAILSDAVHDTG
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DAVAIGLAWFFQKFSKKREDKHFSFGYQRFSLLGASLTSVILITGSFIVLFEAVPRFFNP
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPVEATGMLGLAIFAIVANGFGAWLLARGSSRNESILNLHALEDVLGWLGVLIVSIVLHF
CCCCHHHHHHHHHHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKWYWLDPLLSILIALFILSKAIPKFWGTLRILLESVPEDIDYKNLLRALEQLPEVLAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QLIIWSIDGEQNAAMIHIVIPENQDFSDAKIAVRKLLESEKVCRSAIELDETTDEHKKHV
HHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
QYEI
CCCC
>Mature Secondary Structure 
SLKNKQIKSEHDHNHLDKLVSQNVTIVFALNLFFAILEFIFGVLFNSTAILSDAVHDTG
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DAVAIGLAWFFQKFSKKREDKHFSFGYQRFSLLGASLTSVILITGSFIVLFEAVPRFFNP
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPVEATGMLGLAIFAIVANGFGAWLLARGSSRNESILNLHALEDVLGWLGVLIVSIVLHF
CCCCHHHHHHHHHHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKWYWLDPLLSILIALFILSKAIPKFWGTLRILLESVPEDIDYKNLLRALEQLPEVLAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QLIIWSIDGEQNAAMIHIVIPENQDFSDAKIAVRKLLESEKVCRSAIELDETTDEHKKHV
HHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
QYEI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 9099864 [H]