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The map label for this gene is yljE

Identifier: 15673160

GI number: 15673160

Start: 1194125

End: 1195507

Strand: Direct

Name: yljE

Synonym: L193873

Alternate gene names: 15673160

Gene position: 1194125-1195507 (Clockwise)

Preceding gene: 15673159

Following gene: 15673161

Centisome position: 50.48

GC content: 34.35

Gene sequence:

>1383_bases
ATGTGTTATAATATGGACATGACAAATTTCAAGAAAAACGATATATTTGAAGCAGAAGTCCTTGACTTAACACATGAAGG
ACAAGGGGTTGTTAAAATCGACTCTTTCCCTTTCTTTGTGGATAATGCTTTACCTGGGGAACGTATCAAAATGCATGTGC
TTAAGGTTGGGAAATCTTTTGGATTTGGGCGTGTGGATGAATTTATAAGTCAGAGTAAACATCGTGTTACTCAGCTTAAC
CTTGATTATTTGCGCACCGGAATCGCAGATTTTGGTCATCTATCTTATGATGAACAAGTGAAATTTAAACATAAGCAAGT
AGTAGATATTTTGAGAAAAACAGCTGGTAAATCTGATTATCCAGTTTTACCAGTAGTTGAAGCAATTAAAACAATTAATT
ATCGAAATAAAGCACAAATTCCTGTCCAAATGGTTGACGGGCTTTTAACTACAGGATTTTATCGAAAGAATTCTCATACT
TTGATTCCTGTGGAAGATTTTTATATTCAACATCCTGAGATTGACGCTGTGGTTCTTTTTTTGCGCGATGAGTTTCGAAA
GATTAATTTACAAGCTTATGATGAGAAAACAAGAAAAGGTTGGTTGCGAAATATTGTTGTCCGTCGAGCATTTCACACGG
GTGAAATGATGATTACTTTAGTCGTTACAAGTAAAAAACTTCCAGAAAAGGTTGAACTTGTGATTGATCATTTGGTTGAA
CGTTTTACAAATATAAAATCTGTTCAATTAAATATTAATTCTGGAACAGGTTCATTTATTTTAGGAAAAGAATTTATTTT
ATTATACGGCAAAGATTTCATCACAGATTTGATGCTAGATAAAACTTATCAAATTTCGGCTCCTGCCTTTTATCAAGTTA
ACACACCTCAAGCTGAAAAGCTTTATGAAACTGCCTATGAATTTGCGGGTTTAAAACCAGGTGATGTTGTTATTGATGCA
TACTCTGGAATTGGAACAATTGGAATTAGTATGGCTGATAGAGTTGCAAAAGTCTATGGCATGGAAGTTGTTCCAGCAGC
CGTTGAAAATGCTAAACGTAATGCTCAATTAAATGAACTTGAAAATACACATTATGAGGTTGGAACTGCTGAAAAAATCA
TGCCTAAATGGCTTTCAGAAGGAATAAAACCCGATGTCATTTTTGTTGATCCACCAAGAAAAGGGTTGGATGAAGGCTTT
ATTAAAGCAGCAGCAATGATGAATCCTCGACGTATTGTTTATATTTCTTGTAATCCAGCAACTTTTGCTCGTGATGTTGT
TCGCTTTGAAGCTGATGGTTATTTGCTGGATAAAGTTCAACCAGTTGATTTATTCCCACAAACGCATCATATTGAATTAG
TTGCTAGTTTTAATAAAAAATAA

Upstream 100 bases:

>100_bases
TACACTTTTAACTACATTTTAGGTGAAAGAATTAGGGAATTATGGAGTATATTTTTTCAAAAATTTAAATACTCTTCATT
TATAGGAACCAAATGATAAT

Downstream 100 bases:

>100_bases
AAGAGGATAATAAATCCTATTCATAGAAAGAAAATCATGATTCGCATAACACAAATCAAAATTTCAATTGATGAACCTGT
CAGTAAGGTTAAAAGTCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MCYNMDMTNFKKNDIFEAEVLDLTHEGQGVVKIDSFPFFVDNALPGERIKMHVLKVGKSFGFGRVDEFISQSKHRVTQLN
LDYLRTGIADFGHLSYDEQVKFKHKQVVDILRKTAGKSDYPVLPVVEAIKTINYRNKAQIPVQMVDGLLTTGFYRKNSHT
LIPVEDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRAFHTGEMMITLVVTSKKLPEKVELVIDHLVE
RFTNIKSVQLNINSGTGSFILGKEFILLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAYEFAGLKPGDVVIDA
YSGIGTIGISMADRVAKVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLSEGIKPDVIFVDPPRKGLDEGF
IKAAAMMNPRRIVYISCNPATFARDVVRFEADGYLLDKVQPVDLFPQTHHIELVASFNKK

Sequences:

>Translated_460_residues
MCYNMDMTNFKKNDIFEAEVLDLTHEGQGVVKIDSFPFFVDNALPGERIKMHVLKVGKSFGFGRVDEFISQSKHRVTQLN
LDYLRTGIADFGHLSYDEQVKFKHKQVVDILRKTAGKSDYPVLPVVEAIKTINYRNKAQIPVQMVDGLLTTGFYRKNSHT
LIPVEDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRAFHTGEMMITLVVTSKKLPEKVELVIDHLVE
RFTNIKSVQLNINSGTGSFILGKEFILLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAYEFAGLKPGDVVIDA
YSGIGTIGISMADRVAKVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLSEGIKPDVIFVDPPRKGLDEGF
IKAAAMMNPRRIVYISCNPATFARDVVRFEADGYLLDKVQPVDLFPQTHHIELVASFNKK
>Mature_460_residues
MCYNMDMTNFKKNDIFEAEVLDLTHEGQGVVKIDSFPFFVDNALPGERIKMHVLKVGKSFGFGRVDEFISQSKHRVTQLN
LDYLRTGIADFGHLSYDEQVKFKHKQVVDILRKTAGKSDYPVLPVVEAIKTINYRNKAQIPVQMVDGLLTTGFYRKNSHT
LIPVEDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRAFHTGEMMITLVVTSKKLPEKVELVIDHLVE
RFTNIKSVQLNINSGTGSFILGKEFILLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAYEFAGLKPGDVVIDA
YSGIGTIGISMADRVAKVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLSEGIKPDVIFVDPPRKGLDEGF
IKAAAMMNPRRIVYISCNPATFARDVVRFEADGYLLDKVQPVDLFPQTHHIELVASFNKK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Homo sapiens, GI34222389, Length=418, Percent_Identity=31.1004784688995, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI51173878, Length=418, Percent_Identity=31.1004784688995, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI269784680, Length=420, Percent_Identity=27.8571428571429, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI269784676, Length=420, Percent_Identity=27.8571428571429, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI20149688, Length=420, Percent_Identity=27.8571428571429, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI269784678, Length=284, Percent_Identity=30.2816901408451, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1789148, Length=449, Percent_Identity=26.5033407572383, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787083, Length=282, Percent_Identity=25.531914893617, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790403, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71997438, Length=169, Percent_Identity=33.7278106508876, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322909, Length=152, Percent_Identity=34.2105263157895, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666579, Length=421, Percent_Identity=28.7410926365796, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YLJE_LACLA (Q9CGB9)

Other databases:

- EMBL:   AE005176
- PIR:   B86772
- RefSeq:   NP_267334.1
- ProteinModelPortal:   Q9CGB9
- GeneID:   1114821
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L193873
- NMPDR:   fig|272623.1.peg.1212
- HOGENOM:   HBG690163
- OMA:   RKGCDEA
- ProtClustDB:   CLSK697622
- BioCyc:   LLAC272623:L193873-MONOMER
- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- TIGRFAMs:   TIGR00479

Pfam domain/function: PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 52316; Mature: 52316

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50926 TRAM; PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 417-417 BINDING 292-292 BINDING 321-321 BINDING 342-342 BINDING 390-390

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYNMDMTNFKKNDIFEAEVLDLTHEGQGVVKIDSFPFFVDNALPGERIKMHVLKVGKSF
CEECCCCCCCCCCCCCEEHEEEEEECCCCEEEECCCCEEECCCCCCHHHEEEEEHHCCCC
GFGRVDEFISQSKHRVTQLNLDYLRTGIADFGHLSYDEQVKFKHKQVVDILRKTAGKSDY
CCCHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVLPVVEAIKTINYRNKAQIPVQMVDGLLTTGFYRKNSHTLIPVEDFYIQHPEIDAVVLF
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEECCCCEEEEEHHHEEECCCCCEEEEE
LRDEFRKINLQAYDEKTRKGWLRNIVVRRAFHTGEMMITLVVTSKKLPEKVELVIDHLVE
EECCCCEECEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHH
RFTNIKSVQLNINSGTGSFILGKEFILLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEK
HHCCCEEEEEEEECCCCCEEECCEEEEEECHHHHHHHHHCCCEEECCCEEEEECCCHHHH
LYETAYEFAGLKPGDVVIDAYSGIGTIGISMADRVAKVYGMEVVPAAVENAKRNAQLNEL
HHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
ENTHYEVGTAEKIMPKWLSEGIKPDVIFVDPPRKGLDEGFIKAAAMMNPRRIVYISCNPA
CCCCEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCH
TFARDVVRFEADGYLLDKVQPVDLFPQTHHIELVASFNKK
HHHHHHHEECCCCEEECCCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MCYNMDMTNFKKNDIFEAEVLDLTHEGQGVVKIDSFPFFVDNALPGERIKMHVLKVGKSF
CEECCCCCCCCCCCCCEEHEEEEEECCCCEEEECCCCEEECCCCCCHHHEEEEEHHCCCC
GFGRVDEFISQSKHRVTQLNLDYLRTGIADFGHLSYDEQVKFKHKQVVDILRKTAGKSDY
CCCHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVLPVVEAIKTINYRNKAQIPVQMVDGLLTTGFYRKNSHTLIPVEDFYIQHPEIDAVVLF
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEECCCCEEEEEHHHEEECCCCCEEEEE
LRDEFRKINLQAYDEKTRKGWLRNIVVRRAFHTGEMMITLVVTSKKLPEKVELVIDHLVE
EECCCCEECEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHH
RFTNIKSVQLNINSGTGSFILGKEFILLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEK
HHCCCEEEEEEEECCCCCEEECCEEEEEECHHHHHHHHHCCCEEECCCEEEEECCCHHHH
LYETAYEFAGLKPGDVVIDAYSGIGTIGISMADRVAKVYGMEVVPAAVENAKRNAQLNEL
HHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
ENTHYEVGTAEKIMPKWLSEGIKPDVIFVDPPRKGLDEGFIKAAAMMNPRRIVYISCNPA
CCCCEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCH
TFARDVVRFEADGYLLDKVQPVDLFPQTHHIELVASFNKK
HHHHHHHEECCCCEEECCCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471