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The map label for this gene is ylcA

Identifier: 15673092

GI number: 15673092

Start: 1120067

End: 1121533

Strand: Direct

Name: ylcA

Synonym: L119780

Alternate gene names: 15673092

Gene position: 1120067-1121533 (Clockwise)

Preceding gene: 15673091

Following gene: 15673093

Centisome position: 47.35

GC content: 37.97

Gene sequence:

>1467_bases
ATGGACACTAAAAAAATTAGATGGTTCACCGTCGCATTCATTGCCTTTAACATGGTTTGGGGAATGGGGAATGTTGTCAA
TAACTTTGCCCAACAAGGAATTACTGTTGTTACCTCATGGCTGTTAATTTTGGCTTTGTACTTTATTCCCTATGCACTTA
TTGGTGGTCAACTGGGTTCAACTTTTAAAGATAGTAAAGGTGGGGTCAGTTCATGGGTTGAAAATACCAGTACGAAACGC
TTGGCTTATTATGCCGCATGGACTTATTGGGTAGTTCACATTCCTTATTTGGCTCAAAAACCACAAGCGATTTTGATTGC
TTTTGGTTGGGTGGGTCAAGGAAACGGAAATCTGGTCAGTCAAATGTCGATGACCGCTGTTGCTCTTATTTCATTAGCGA
TTTTTTTAGCTTTCTTATGGTTGTCAACAAAAGGGTTAAGTACTCTGAAAGTGATTGGTGGACTTGCGGGAACAGCAATG
TTTGTTATGAGTTTACTTTTCATTGTCATGGCGATTGGAGCACCTTTTATCGCAAAAGATTTCCACATTGCAACGCCTGA
CATGGGAAATATTAAAACTTATATCCCTAAATTTGACTTCAGTTATTTCACAACTATCTCAATGCTGGTTTTTGCTGTCG
GTGGTGCTGAAAAAATTTCTCCTTATGTTAATCAAACGAAAAACCCAGCAAAAGAATTTCCAAGAGGGATGTTTTTACTT
GCTGGAATGGTTGGTATCTGTGCCGTTTTAGGTTCGATTGCCATGGGAATGATTTTCTCAAGCGGTAATTTACCAAATGA
TTTAATGGCTAACGGTGCTTATGCCGCATTCCAAATTTTAGGTCAACACTTTGGTGTCGGAAACTTTTTAATGATTGTTT
ATGCTTTAACTAACGGTGTAGGACAAATTGCTGCCTTAGCTTTCTCTATTGATGCGCCATTACGCATTTTACTTGCTGAT
GCTGACCCAGAATTCGTTTCAGCATGGTTGCGTAAAAAAACGAACAAAGGAACGCTTAAAAATGGTTATACATTAACAGG
GATTCTTGTAAGTATCATTATTCTTTTACCGTTACTTGGAATCGGAGATATGAATGAATTAGTCAAATGGTTGACTAATT
TAAATTCAGTTGTGATGCCAATGCGTTATCTTTGGGTCTTCTTTGCCTTCATTATGTTAAATCGGGCAGTAAAACATTTT
CAATCTGAATATAAATTTATCAAACAAAAACGTCTAGCCATGATTGCTGGTGCTTGGTGTTTCCTCTTTACACTCATCGC
CTGCGTGTTAGGGATGGTTCCAAAATTGGACTATGCTGCTAATCCATCTGCATGGTGGTTCCAAATTGCATCGAATATTT
TGACACCAATTGTTTTAATTTTACTTGGTATGCTTTTGCCTTTCATTGCTCGTCGTGAACAACGCAAAACAAATGGTCTT
GATTTAAATTCGCTCAATGTGGAATAA

Upstream 100 bases:

>100_bases
AGACTGTAATATTTTATAATTTTAATGACGCTTAAAAGAAAGCGCTAAACAATAAATTGTCAATGTCCGCAATTTATTCA
AAAAACACGTAAGGAGTTTT

Downstream 100 bases:

>100_bases
AGCCAGATTATCCCTGATTTTTTCAGGGTTTTTTGATGTTTTTTTTAGAATAAAACAAAAGGATAAGTATTCTTAAAAAT
ATCTAAGGATAAATTGTAAA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MDTKKIRWFTVAFIAFNMVWGMGNVVNNFAQQGITVVTSWLLILALYFIPYALIGGQLGSTFKDSKGGVSSWVENTSTKR
LAYYAAWTYWVVHIPYLAQKPQAILIAFGWVGQGNGNLVSQMSMTAVALISLAIFLAFLWLSTKGLSTLKVIGGLAGTAM
FVMSLLFIVMAIGAPFIAKDFHIATPDMGNIKTYIPKFDFSYFTTISMLVFAVGGAEKISPYVNQTKNPAKEFPRGMFLL
AGMVGICAVLGSIAMGMIFSSGNLPNDLMANGAYAAFQILGQHFGVGNFLMIVYALTNGVGQIAALAFSIDAPLRILLAD
ADPEFVSAWLRKKTNKGTLKNGYTLTGILVSIIILLPLLGIGDMNELVKWLTNLNSVVMPMRYLWVFFAFIMLNRAVKHF
QSEYKFIKQKRLAMIAGAWCFLFTLIACVLGMVPKLDYAANPSAWWFQIASNILTPIVLILLGMLLPFIARREQRKTNGL
DLNSLNVE

Sequences:

>Translated_488_residues
MDTKKIRWFTVAFIAFNMVWGMGNVVNNFAQQGITVVTSWLLILALYFIPYALIGGQLGSTFKDSKGGVSSWVENTSTKR
LAYYAAWTYWVVHIPYLAQKPQAILIAFGWVGQGNGNLVSQMSMTAVALISLAIFLAFLWLSTKGLSTLKVIGGLAGTAM
FVMSLLFIVMAIGAPFIAKDFHIATPDMGNIKTYIPKFDFSYFTTISMLVFAVGGAEKISPYVNQTKNPAKEFPRGMFLL
AGMVGICAVLGSIAMGMIFSSGNLPNDLMANGAYAAFQILGQHFGVGNFLMIVYALTNGVGQIAALAFSIDAPLRILLAD
ADPEFVSAWLRKKTNKGTLKNGYTLTGILVSIIILLPLLGIGDMNELVKWLTNLNSVVMPMRYLWVFFAFIMLNRAVKHF
QSEYKFIKQKRLAMIAGAWCFLFTLIACVLGMVPKLDYAANPSAWWFQIASNILTPIVLILLGMLLPFIARREQRKTNGL
DLNSLNVE
>Mature_488_residues
MDTKKIRWFTVAFIAFNMVWGMGNVVNNFAQQGITVVTSWLLILALYFIPYALIGGQLGSTFKDSKGGVSSWVENTSTKR
LAYYAAWTYWVVHIPYLAQKPQAILIAFGWVGQGNGNLVSQMSMTAVALISLAIFLAFLWLSTKGLSTLKVIGGLAGTAM
FVMSLLFIVMAIGAPFIAKDFHIATPDMGNIKTYIPKFDFSYFTTISMLVFAVGGAEKISPYVNQTKNPAKEFPRGMFLL
AGMVGICAVLGSIAMGMIFSSGNLPNDLMANGAYAAFQILGQHFGVGNFLMIVYALTNGVGQIAALAFSIDAPLRILLAD
ADPEFVSAWLRKKTNKGTLKNGYTLTGILVSIIILLPLLGIGDMNELVKWLTNLNSVVMPMRYLWVFFAFIMLNRAVKHF
QSEYKFIKQKRLAMIAGAWCFLFTLIACVLGMVPKLDYAANPSAWWFQIASNILTPIVLILLGMLLPFIARREQRKTNGL
DLNSLNVE

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081798, Length=476, Percent_Identity=57.7731092436975, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI48994921, Length=419, Percent_Identity=23.3890214797136, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082380, Length=443, Percent_Identity=21.2189616252822, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53724; Mature: 53724

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKKIRWFTVAFIAFNMVWGMGNVVNNFAQQGITVVTSWLLILALYFIPYALIGGQLGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TFKDSKGGVSSWVENTSTKRLAYYAAWTYWVVHIPYLAQKPQAILIAFGWVGQGNGNLVS
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEECEECCCCCHHH
QMSMTAVALISLAIFLAFLWLSTKGLSTLKVIGGLAGTAMFVMSLLFIVMAIGAPFIAKD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
FHIATPDMGNIKTYIPKFDFSYFTTISMLVFAVGGAEKISPYVNQTKNPAKEFPRGMFLL
CEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHCHHHHCCCCCHHHCCHHHHHH
AGMVGICAVLGSIAMGMIFSSGNLPNDLMANGAYAAFQILGQHFGVGNFLMIVYALTNGV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCH
GQIAALAFSIDAPLRILLADADPEFVSAWLRKKTNKGTLKNGYTLTGILVSIIILLPLLG
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
IGDMNELVKWLTNLNSVVMPMRYLWVFFAFIMLNRAVKHFQSEYKFIKQKRLAMIAGAWC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFTLIACVLGMVPKLDYAANPSAWWFQIASNILTPIVLILLGMLLPFIARREQRKTNGL
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLNSLNVE
CCCCCCCC
>Mature Secondary Structure
MDTKKIRWFTVAFIAFNMVWGMGNVVNNFAQQGITVVTSWLLILALYFIPYALIGGQLGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TFKDSKGGVSSWVENTSTKRLAYYAAWTYWVVHIPYLAQKPQAILIAFGWVGQGNGNLVS
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEECEECCCCCHHH
QMSMTAVALISLAIFLAFLWLSTKGLSTLKVIGGLAGTAMFVMSLLFIVMAIGAPFIAKD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
FHIATPDMGNIKTYIPKFDFSYFTTISMLVFAVGGAEKISPYVNQTKNPAKEFPRGMFLL
CEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHCHHHHCCCCCHHHCCHHHHHH
AGMVGICAVLGSIAMGMIFSSGNLPNDLMANGAYAAFQILGQHFGVGNFLMIVYALTNGV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCH
GQIAALAFSIDAPLRILLADADPEFVSAWLRKKTNKGTLKNGYTLTGILVSIIILLPLLG
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
IGDMNELVKWLTNLNSVVMPMRYLWVFFAFIMLNRAVKHFQSEYKFIKQKRLAMIAGAWC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFTLIACVLGMVPKLDYAANPSAWWFQIASNILTPIVLILLGMLLPFIARREQRKTNGL
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLNSLNVE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]