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The map label for this gene is mraY

Identifier: 15672850

GI number: 15672850

Start: 891698

End: 892687

Strand: Direct

Name: mraY

Synonym: L91444

Alternate gene names: 15672850

Gene position: 891698-892687 (Clockwise)

Preceding gene: 15672849

Following gene: 15672851

Centisome position: 37.69

GC content: 36.97

Gene sequence:

>990_bases
ATGTTATTGAATGGGATAGTGGCGGCGGTAATTACAATGATTATAACAATCATTGGTATTCCTCGCTTCATTATGTTCTT
CCACAAGAAAAAATTGGGTGGGCAACCAACCCTTGAAGATGTAAAACAGCATGCAAGTAAAGCTGGGACTCCTACAATGG
GCGGTTTTGTCTTCGTTGTTGTGAGTTTAGTAGTTTCATTAATTGCCGCTTTGGTTTTTGGCAAATTTAGTCCAGCTTTC
ATTACTGCGTGGTGGGTCTTTGCCATGTATGCTGTCATTGGCTTCTTAGATGACTTTTTGAAAGTATTCAAACAAATTAA
TGAAGGTTTGACTGCCAAACAAAAAATGTTGGCTCAAATTTTAATTGGGATTGTTTCCTATTTCATTTATAGTCATGGGG
AAAAATCTCATATTATTCATCTTTTAAGTTGGGAATTTAATATTGGGATTTTCTTTTCAATTTTCATTATTATTTGGCTT
GTGGGTTGGTCAAATGCGGTCAATCTTACTGACGGAATCGACGGTCTTGCTTCAATCACTGTTGCGATTTCACTGACAGC
TTATGCAGTTATCGCAGTAGCACATCAACAGTACGATGTTTTGTTGATTATCTTGTCAGTCATTGGTGGTTTGCTTGGAT
TCTTTGTCTTCAATCACAAACCAGCAAAAATTTTCATGGGTGATGTTGGTTCCTTGGCTTTGGGTGGTTTTCTTGCAATT
GTTTCAATCTTACTTCATGCCGAATGGACTTTGCTTTTAATTGGTGCGGTTTATGTCATTGAAACACTTTCAGTGATGCT
ACAAGTTGCTTATTTCAAGAAAACAGGTGGTAAACGTATTTTTAGAATGACTCCTATTCATCATCATTTTGAACTCGGTG
GATTTTCTGGAAAAGCAGCTGGTTGGTCAGAATGGAAAATTGACATTGTCTTCTGGTTATTTACAGCAGTGCTGTCAGTA
ATTGCGCTTTGTATTTACTTTGCTTTTTAA

Upstream 100 bases:

>100_bases
AAAGGTCAAACTCTAACTGTTAAAATGGGAAATTAAAAATTATTAATTGAGGCTCCACAGACACTAGTCTATGTGGAGCT
TCAAAAATTAGGAGAAGAAA

Downstream 100 bases:

>100_bases
TTAATAAATTTACTGACAGAATGGTCAGTGAAAAGTCGCTCTTGTGAGCGACTTTTTTTTATTTTTTAAAGTTAATATTT
TACTGACAGAATACTCAAGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLIAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF

Sequences:

>Translated_329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLIAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF
>Mature_329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLIAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=342, Percent_Identity=35.9649122807018, Blast_Score=177, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_LACLA (Q9CH70)

Other databases:

- EMBL:   AE005176
- PIR:   D86733
- RefSeq:   NP_267024.1
- GeneID:   1114497
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L91444
- NMPDR:   fig|272623.1.peg.889
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   LLAC272623:L91444-MONOMER
- BRENDA:   2.7.8.13
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 36257; Mature: 36257

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd820270)-; HASH(0xda29bb4)-; HASH(0xd71efdc)-; HASH(0xd79bfb0)-; HASH(0xd617b3c)-; HASH(0xbe64af4)-; HASH(0xd760c94)-; HASH(0xdd3a53c)-; HASH(0xb89b4b4)-; HASH(0xda1ce6c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
VSLVVSLIAALVFGKFSPAFITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWLVGWSNAVNLTDGIDGLASIT
HHHHHHHHHHCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHEECCCCCCCC
GWSEWKIDIVFWLFTAVLSVIALCIYFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
VSLVVSLIAALVFGKFSPAFITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWLVGWSNAVNLTDGIDGLASIT
HHHHHHHHHHCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHEECCCCCCCC
GWSEWKIDIVFWLFTAVLSVIALCIYFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471