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The map label for this gene is yicB

Identifier: 15672793

GI number: 15672793

Start: 822669

End: 823478

Strand: Direct

Name: yicB

Synonym: L22687

Alternate gene names: 15672793

Gene position: 822669-823478 (Clockwise)

Preceding gene: 15672792

Following gene: 15672794

Centisome position: 34.78

GC content: 32.22

Gene sequence:

>810_bases
ATGAATAAAGAAATTAAACTCATTGCCCTAGATTTGGATGGGACCTTACTCAACTCTTCAAAAGAAATTTCAAAAGAAAA
TCGTCTGGCTATTAATGCAGCAAGACAAAAAGGGGTCCAGGTTGTTTTAACAACGGGGCGTCCTTTGATTGCAATTCAAC
CCTTTCTCAAAACCTTAGAAATGCTTGATTTTGAAGATTTTTCAATTACCTTTAATGGTGGTCTGGTCCAAAGAAATACG
GGTCAAATCTTATCTAAAAAAAGTTTTTCACATGATGAAATTTTAGAAATTAAAGAATTGACTTCAAATCTTGGCATTCC
TTGCGATGTTTTGAGTGAAGAAAAAGTTTATATGACGAAAAGTAAAATTGACTCGCAATATGACACTTTAAATAAGCTTT
TAACTTTTATCAAAGTTGATTTTGATCAAGTTCCACTTGATGTGGTTTATAATAAGATTGTTTCTTGTACAGAAAAAGAA
TTGTTGGACGCTAGTCTTGATAAAATTCCTGAATCTTATTTTGACCAATTTGAGATTTTTAAAACTCAAGCGAAGCTTTT
AGAATTTATGCCAAAAGGAATTAATAAAGCTTATGGTTTGACACAATTGATTAATCAGTTAAACTTAAAACCAGAAAATG
TAATGGCCATGGGAGATGAAGCAAACGATTTATCAATGATTTCTTGGGCAGGATATGGTGTTGCTATGGCGAATGCTGTC
CCAGCAGTTAAAGAAGAAGCAAGAATTATTTCTGATTTAACTAATGACCAACACGCTGTTGCTCATATTATTGAAAAATA
TGTACTCTAA

Upstream 100 bases:

>100_bases
ACTTCATTGTTTTTATTGCCCTAGATTTAGTTCCAAACAAAATGTCTGACTTTAGTGAGCATTATTGAACCTGACTGATA
CAGTGTGCTATAATTAAACA

Downstream 100 bases:

>100_bases
GGACTAATAATGAAAGATGAAGTTCAACTAAAAAAGTATTTGCCGAGTTTAATTTTTGCGATTATTTTACCAGTTATTGC
CTATTTGTTTTTAAAAATGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNKEIKLIALDLDGTLLNSSKEISKENRLAINAARQKGVQVVLTTGRPLIAIQPFLKTLEMLDFEDFSITFNGGLVQRNT
GQILSKKSFSHDEILEIKELTSNLGIPCDVLSEEKVYMTKSKIDSQYDTLNKLLTFIKVDFDQVPLDVVYNKIVSCTEKE
LLDASLDKIPESYFDQFEIFKTQAKLLEFMPKGINKAYGLTQLINQLNLKPENVMAMGDEANDLSMISWAGYGVAMANAV
PAVKEEARIISDLTNDQHAVAHIIEKYVL

Sequences:

>Translated_269_residues
MNKEIKLIALDLDGTLLNSSKEISKENRLAINAARQKGVQVVLTTGRPLIAIQPFLKTLEMLDFEDFSITFNGGLVQRNT
GQILSKKSFSHDEILEIKELTSNLGIPCDVLSEEKVYMTKSKIDSQYDTLNKLLTFIKVDFDQVPLDVVYNKIVSCTEKE
LLDASLDKIPESYFDQFEIFKTQAKLLEFMPKGINKAYGLTQLINQLNLKPENVMAMGDEANDLSMISWAGYGVAMANAV
PAVKEEARIISDLTNDQHAVAHIIEKYVL
>Mature_269_residues
MNKEIKLIALDLDGTLLNSSKEISKENRLAINAARQKGVQVVLTTGRPLIAIQPFLKTLEMLDFEDFSITFNGGLVQRNT
GQILSKKSFSHDEILEIKELTSNLGIPCDVLSEEKVYMTKSKIDSQYDTLNKLLTFIKVDFDQVPLDVVYNKIVSCTEKE
LLDASLDKIPESYFDQFEIFKTQAKLLEFMPKGINKAYGLTQLINQLNLKPENVMAMGDEANDLSMISWAGYGVAMANAV
PAVKEEARIISDLTNDQHAVAHIIEKYVL

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates erythrose 4-phosphate and mannose 1-phosphate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=269, Percent_Identity=37.1747211895911, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1787043, Length=257, Percent_Identity=24.5136186770428, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994981, Length=272, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081790, Length=271, Percent_Identity=25.0922509225092, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 30166; Mature: 30166

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEIKLIALDLDGTLLNSSKEISKENRLAINAARQKGVQVVLTTGRPLIAIQPFLKTLE
CCCCEEEEEEECCCCCCCCCHHHCCHHHEEEEHHHHCCCEEEEECCCCEEEHHHHHHHHH
MLDFEDFSITFNGGLVQRNTGQILSKKSFSHDEILEIKELTSNLGIPCDVLSEEKVYMTK
HHCCCCEEEEECCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEH
SKIDSQYDTLNKLLTFIKVDFDQVPLDVVYNKIVSCTEKELLDASLDKIPESYFDQFEIF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KTQAKLLEFMPKGINKAYGLTQLINQLNLKPENVMAMGDEANDLSMISWAGYGVAMANAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHC
PAVKEEARIISDLTNDQHAVAHIIEKYVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKEIKLIALDLDGTLLNSSKEISKENRLAINAARQKGVQVVLTTGRPLIAIQPFLKTLE
CCCCEEEEEEECCCCCCCCCHHHCCHHHEEEEHHHHCCCEEEEECCCCEEEHHHHHHHHH
MLDFEDFSITFNGGLVQRNTGQILSKKSFSHDEILEIKELTSNLGIPCDVLSEEKVYMTK
HHCCCCEEEEECCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEH
SKIDSQYDTLNKLLTFIKVDFDQVPLDVVYNKIVSCTEKELLDASLDKIPESYFDQFEIF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KTQAKLLEFMPKGINKAYGLTQLINQLNLKPENVMAMGDEANDLSMISWAGYGVAMANAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHC
PAVKEEARIISDLTNDQHAVAHIIEKYVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]