Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 15672759

GI number: 15672759

Start: 786486

End: 786920

Strand: Direct

Name: fabZ

Synonym: L0188

Alternate gene names: 15672759

Gene position: 786486-786920 (Clockwise)

Preceding gene: 15672758

Following gene: 15672760

Centisome position: 33.25

GC content: 37.7

Gene sequence:

>435_bases
ATGACTGAAGTAAACATTAATGTAACTGAAATTATGGAGGCTTTGCCTCATCGTTATCCATTTCTATTAGTCGATCGTGT
GATTGATATTGCTGAGGATGAAATTACAGCAATTAAAAATGTGACGATTAATGAAGAATTTTTCCAAGGACATTTTCCAC
AATATCCAGTAATGCCAGGGGTTTTGATTATGGAAGCTCTCGCACAAGCGGCTGGTGTTTTAGAATTATCTAAACCTGAA
AACAAAGGAAAACTTGTTTTTTATGCGGGAATGGACAATGTTAAGTACAAAAAACAAGTCACTCCCGGAGATCAATTGGT
CTTACATGCTAAATTTATCAAACGTCGTGGTCCAATTGCGGTTGTTGAAGCAGAAGCAACTGTTGATGGAAAATTGGCGG
CTAAAGGAACTTTGACTTTTGCCTTAGGGCGTTAG

Upstream 100 bases:

>100_bases
TTTATCTTTGATGTAAAAGTTACTGACAGCTCTGGTTTAGGTGCCAGAGAATTTACTGACAAGTTCTGTCAGTGAATCTC
TAAAAGAAAAGTGAGAATAA

Downstream 100 bases:

>100_bases
TGCTTTAGTACTTGCCTTTTTATCACTTGCTTTAGCAAGTAGAGAAAACGGACAGCGAAACGAAGTGGAGATAGGCTTAT
AACCATTACGACTAATCGCT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase 2

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MTEVNINVTEIMEALPHRYPFLLVDRVIDIAEDEITAIKNVTINEEFFQGHFPQYPVMPGVLIMEALAQAAGVLELSKPE
NKGKLVFYAGMDNVKYKKQVTPGDQLVLHAKFIKRRGPIAVVEAEATVDGKLAAKGTLTFALGR

Sequences:

>Translated_144_residues
MTEVNINVTEIMEALPHRYPFLLVDRVIDIAEDEITAIKNVTINEEFFQGHFPQYPVMPGVLIMEALAQAAGVLELSKPE
NKGKLVFYAGMDNVKYKKQVTPGDQLVLHAKFIKRRGPIAVVEAEATVDGKLAAKGTLTFALGR
>Mature_143_residues
TEVNINVTEIMEALPHRYPFLLVDRVIDIAEDEITAIKNVTINEEFFQGHFPQYPVMPGVLIMEALAQAAGVLELSKPEN
KGKLVFYAGMDNVKYKKQVTPGDQLVLHAKFIKRRGPIAVVEAEATVDGKLAAKGTLTFALGR

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=45.4545454545455, Blast_Score=137, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ2_LACLA (Q9CHF4)

Other databases:

- EMBL:   AE005176
- PIR:   A86722
- RefSeq:   NP_266933.1
- ProteinModelPortal:   Q9CHF4
- SMR:   Q9CHF4
- GeneID:   1114404
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0188
- NMPDR:   fig|272623.1.peg.797
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   LLAC272623:L0188-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15924; Mature: 15793

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVNINVTEIMEALPHRYPFLLVDRVIDIAEDEITAIKNVTINEEFFQGHFPQYPVMPG
CCEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEECHHHHCCCCCCCCCCCH
VLIMEALAQAAGVLELSKPENKGKLVFYAGMDNVKYKKQVTPGDQLVLHAKFIKRRGPIA
HHHHHHHHHHHCEEEECCCCCCCCEEEEECCCCCEEEEECCCCHHEEEEHHHHHCCCCEE
VVEAEATVDGKLAAKGTLTFALGR
EEEECCCCCCEEEECCEEEEEECC
>Mature Secondary Structure 
TEVNINVTEIMEALPHRYPFLLVDRVIDIAEDEITAIKNVTINEEFFQGHFPQYPVMPG
CEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEECHHHHCCCCCCCCCCCH
VLIMEALAQAAGVLELSKPENKGKLVFYAGMDNVKYKKQVTPGDQLVLHAKFIKRRGPIA
HHHHHHHHHHHCEEEECCCCCCCCEEEEECCCCCEEEEECCCCHHEEEEHHHHHCCCCEE
VVEAEATVDGKLAAKGTLTFALGR
EEEECCCCCCEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471