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The map label for this gene is nrdR

Identifier: 15672732

GI number: 15672732

Start: 757068

End: 757514

Strand: Direct

Name: nrdR

Synonym: L157023

Alternate gene names: 15672732

Gene position: 757068-757514 (Clockwise)

Preceding gene: 15672731

Following gene: 15672733

Centisome position: 32.0

GC content: 36.02

Gene sequence:

>447_bases
ATGAGATGTCCAAAGTGTTCTTCTGAAGAATCAAAAGTTGTTGATTCAAGACAAGCCGAAGATGCTATTCGCCGTCGTCG
TGTTTGTGAATCATGTGGTTTTCGCTTCACAACCTTTGAACGTATCGAAGAAATGCCCCTTTTAGTCATCAAAAAAGATG
ACAAACGTGAACCCTTTAATCGTGAAAAAATTGTTCGTGGTTTAGTTCGTTCAGCATACAAACGCCCAGTATCAAGTGAA
GATATTGAAACAACAGTTGCAAATGTTGAAAGAAAAATTCGTCAACTAGACAGTAATGAAGTTGAATCAGATGTTATTGG
TGAATTTGTGATGCAAGAATTAGCTGAATTGGATGATATCACCTATATCAGATTTGCCAGCGTCTATCGTTCATTCAAAG
ATGTCAGTGAATTAGAAGAGCTCCTTAAAAATATTACCAAAAAATAA

Upstream 100 bases:

>100_bases
TTAAAACTAATGAAAAAAATTACTGACAGAATAAGAAAGTCTAAACCAATTTTCTGTCAGTAAAATTAATAAGAATTTAT
TATCTATTAAGGAGAATAAA

Downstream 100 bases:

>100_bases
ATCCGTCAGTAAAAAGTGACTGAATAAGGAGCATTTTATCGGCAAATAAAAGAAAGATCAGCTTGCTGAACTTTCTGTCA
GTAAAATGCGGCTGAATAGA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFNREKIVRGLVRSAYKRPVSSE
DIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDITYIRFASVYRSFKDVSELEELLKNITKK

Sequences:

>Translated_148_residues
MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFNREKIVRGLVRSAYKRPVSSE
DIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDITYIRFASVYRSFKDVSELEELLKNITKK
>Mature_148_residues
MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFNREKIVRGLVRSAYKRPVSSE
DIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDITYIRFASVYRSFKDVSELEELLKNITKK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=47.1830985915493, Blast_Score=133, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_LACLA (Q9CHI1)

Other databases:

- EMBL:   AE005176
- PIR:   F86718
- RefSeq:   NP_266906.1
- GeneID:   1114376
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L157023
- NMPDR:   fig|272623.1.peg.769
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   LLAC272623:L157023-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17374; Mature: 17374

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCCCC
REKIVRGLVRSAYKRPVSSEDIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TYIRFASVYRSFKDVSELEELLKNITKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCCCC
REKIVRGLVRSAYKRPVSSEDIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TYIRFASVYRSFKDVSELEELLKNITKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471