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The map label for this gene is efp

Identifier: 15672674

GI number: 15672674

Start: 691623

End: 692180

Strand: Direct

Name: efp

Synonym: L0377

Alternate gene names: 15672674

Gene position: 691623-692180 (Clockwise)

Preceding gene: 15672673

Following gene: 15672675

Centisome position: 29.24

GC content: 36.02

Gene sequence:

>558_bases
ATGGTTTTAGCAAAAGACCTTAAATCAGGCATGACATTTTTGAATGGGGAAAAACTTCTCCGCGTTATGGAAGCAAGTCA
TCACAAACCAGGTAAAGGGAATACAATCATGCGTATGAAACTTAAAGACGTACGCTCAGGTTCAACTTTTGATGACACTT
ACCGTCCTGAAGATAAGTTTGAACAAGCTGTTATTGAAACTGTAACAGCACAATACCTCTACTCAATGGATGGTATTGCT
AATTTCATGAACAATGAAACTTACGAACAATATGAAATTCCAGTAGAACAAGTTAAAGATGAACTTCTTTATGTTCTTGA
AAATACAGATGTTAAAATTCAATTCTACGGTACAGAAGTAATTGGTATTCAACTTCCAACAACAGTTGTTCTTGAAGTTA
CTGAAACACAACCATCTATTAAAGGTGCAACAGTAACAGGTTCTGGTAAACCAGCAACTATGGAAACTGGTCTTGTTGTT
AACGTTCCTGATTTCGTTGAAGCTGGGACAAAACTTGAAATCAACACACAAACAGGTGAATACTTGAAACGTGCTTAA

Upstream 100 bases:

>100_bases
TTAAATCCTGTCATTTCACTTCTTTTGTGTACAGAAAAATTGCTGACAAAAGAAAAATGACAGAATATCTAAATTTATAA
ATACTAGGAGAAACATAAAC

Downstream 100 bases:

>100_bases
TTAAGTACGATTACTGAAAAAAGTTACTGACAGCCTTTTGTCAGTAACTTTATGAAGTTTAAAGACTTCGTCAGTAAAGA
AAATTCATTTTGTAAGTGAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKFEQAVIETVTAQYLYSMDGIA
NFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEVIGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVV
NVPDFVEAGTKLEINTQTGEYLKRA

Sequences:

>Translated_185_residues
MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKFEQAVIETVTAQYLYSMDGIA
NFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEVIGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVV
NVPDFVEAGTKLEINTQTGEYLKRA
>Mature_185_residues
MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKFEQAVIETVTAQYLYSMDGIA
NFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEVIGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVV
NVPDFVEAGTKLEINTQTGEYLKRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=34.4262295081967, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=31.2169312169312, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_LACLA (Q9CHN6)

Other databases:

- EMBL:   AE005176
- PIR:   D86711
- RefSeq:   NP_266848.1
- ProteinModelPortal:   Q9CHN6
- SMR:   Q9CHN6
- PhosSite:   Q9CHN6
- GeneID:   1114317
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0377
- NMPDR:   fig|272623.1.peg.710
- HOGENOM:   HBG303311
- OMA:   VVIMTAD
- ProtClustDB:   PRK00529
- BioCyc:   LLAC272623:L0377-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20654; Mature: 20654

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKF
CCCHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHH
EQAVIETVTAQYLYSMDGIANFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHEEEEECCCEEEEEECCEE
IGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVVNVPDFVEAGTKLEINTQTGE
EEEECCCEEEEEEECCCCCCCCEEEECCCCCCEEECCEEEECCHHHHCCCEEEEECCCHH
YLKRA
HHHCC
>Mature Secondary Structure
MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKF
CCCHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHH
EQAVIETVTAQYLYSMDGIANFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHEEEEECCCEEEEEECCEE
IGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVVNVPDFVEAGTKLEINTQTGE
EEEECCCEEEEEEECCCCCCCCEEEECCCCCCEEECCEEEECCHHHHCCCEEEEECCCHH
YLKRA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471