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The map label for this gene is iscS [C]

Identifier: 15669874

GI number: 15669874

Start: 1660933

End: 1662123

Strand: Direct

Name: iscS [C]

Synonym: MJ1678

Alternate gene names: 15669874

Gene position: 1660933-1662123 (Clockwise)

Preceding gene: 15669873

Following gene: 15669875

Centisome position: 99.76

GC content: 35.85

Gene sequence:

>1191_bases
ATGGAATTAGAGGGGCCTTACTCTAAAAAATTTGAGGTGATTACTTTGGATATAAACTTGGATAAATACAAAAACTTAAC
AAGAAGCTTGACAAGGGAATTTATTAACTTAAATCCAATACAGAGAGGAGGCATTTTACCAAAAGAGGCTAAGAAGGCAG
TTTATGAATATTGGGACGGTTATAGCGTTTGCGATTACTGCCATGGAAGATTGGATGAGGTTACATGCCCACCAATAAAG
GACTTTTTGGAAGATATTGCCAAGTTTTTAAATATGGACTGTGCAAGACCTACACACGGGGCAAGGGAAGGAAAATTTAT
TGTTATGCACGCCATATGTAAAGAAGGAGATTATGTAGTTTTAGATAAAAATGCTCACTACACAAGTTATGTTGCCGCTG
AAAGAGCTAAGCTAAACGTTGCAGAGGTTGGCTATGAAGAGGAGTATCCAACATATAAGATAAACTTAGAGGGTTATAAG
GAGGTTATAGATAATTTAGAGGACAAGGGAAAAAATGTCGGATTGATATTATTAACTCATGTAGATGGAGAGTATGGGAA
CCTAAACGATGCAAAAAAAGTTGGTAAAATAGCTAAAGAAAAAGGCATCCCATTCCTACTAAATTGTGCATATACAGTTG
GAAGAATGCCAGTCAATGGAAAGGAAGTTAAGGCTGATTTTATTGTTGCATCAGGGCATAAGAGTATGGCAGCATCAGCT
CCATGTGGTATTTTGGCATTTAGTGAGGAATTTTCCGATAAAATAACAAAAACATCAGAGAAATTCCCAGTTAAAGAAAT
TGAGATGCTTGGATGCACAAGTAGAGGACTGCCAATAGTTACTTTAATGGCAAGCTTTCCTCATGTTGTTGAAAGGGTTA
AAAAATGGGATGAAGAGCTTAAAAAAACAAGATATGTTGTTGATGAACTTGAAAAGATTGGATTTAAGCAGTTAGGAATT
AAACCAAAAGAACACGATTTAATTAAATTTGAAACACCAGTATTGGATGAGATAGCTAAAAAGGATAAGAGGAGAGGGTT
TTTCTTCTATGATGAGTTGAAGAAGAGGGGAATTGGAGGGATTAGAGCAGGAGTTACTAAGGAGATTAAGATGAGTGTCT
ATGGATTAGAATGGGAACAGGTTGAGTATGTTGTTAATGCAATAAAGGAGATTGTTGAGAGTTGTAAATAA

Upstream 100 bases:

>100_bases
GCTGAGAGTGTTTTAGATAGGATTGGAAGATTGGGGATTAGGATATTAACAAGAATGATGGGTTTGATATTAACAGCAAT
AGCAGTTCAGATGATAGTTA

Downstream 100 bases:

>100_bases
TTTGGTGATGCTATGATTGAAGAAGAAATAACTCTTAAGATTCCAAAAAGTATCGTTAATCAAATAGATGAGCTTATTAA
AGAAGGGTATTTTAGCAGTA

Product: Sep-tRNA:Cys-tRNA synthetase

Products: NA

Alternate protein names: Sep-tRNA:Cys-tRNA synthase; SepCysS [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MELEGPYSKKFEVITLDINLDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDGYSVCDYCHGRLDEVTCPPIK
DFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVVLDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYK
EVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASA
PCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEELKKTRYVVDELEKIGFKQLGI
KPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGGIRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK

Sequences:

>Translated_396_residues
MELEGPYSKKFEVITLDINLDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDGYSVCDYCHGRLDEVTCPPIK
DFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVVLDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYK
EVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASA
PCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEELKKTRYVVDELEKIGFKQLGI
KPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGGIRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK
>Mature_396_residues
MELEGPYSKKFEVITLDINLDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDGYSVCDYCHGRLDEVTCPPIK
DFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVVLDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYK
EVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASA
PCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEELKKTRYVVDELEKIGFKQLGI
KPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGGIRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK

Specific function: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) [H]

COG id: COG1103

COG function: function code R; Archaea-specific pyridoxal phosphate-dependent enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SepCysS family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR013375
- InterPro:   IPR008829 [H]

Pfam domain/function: PF05889 SLA_LP_auto_ag [H]

EC number: =2.5.1.73 [H]

Molecular weight: Translated: 44955; Mature: 44955

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEGPYSKKFEVITLDINLDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDG
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
YSVCDYCHGRLDEVTCPPIKDFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVV
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEE
LDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYKEVIDNLEDKGKNVGLILLTH
EECCCCCHHHHHHHHHHCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEE
VDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHCCCCCCCCEEEEEEEEECCCCHHHCCC
PCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEEL
CCCEEEECHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGG
HHHHHHHHHHHHCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEHHHHHHCCCCC
IRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELEGPYSKKFEVITLDINLDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDG
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
YSVCDYCHGRLDEVTCPPIKDFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVV
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEE
LDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYKEVIDNLEDKGKNVGLILLTH
EECCCCCHHHHHHHHHHCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEE
VDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHCCCCCCCCEEEEEEEEECCCCHHHCCC
PCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEEL
CCCEEEECHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGG
HHHHHHHHHHHHCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEHHHHHHCCCCC
IRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]