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The map label for this gene is 15669754

Identifier: 15669754

GI number: 15669754

Start: 1534694

End: 1535260

Strand: Direct

Name: 15669754

Synonym: MJ1559

Alternate gene names: NA

Gene position: 1534694-1535260 (Clockwise)

Preceding gene: 15669752

Following gene: 15669759

Centisome position: 92.18

GC content: 29.63

Gene sequence:

>567_bases
ATGATTTATAACTTTAAACATTACATACATCAATTTAAGGGTTGTGGTGAAACTATGAGGATATTTATAACGGGAATGCC
CGGAGTTGGAAAAACTACATTAGCTTTAAAGATAGCTGAGAAGTTGAAGGAGTTAGGCTATAAAGTTGGAGGTTTTATAA
CTAAGGAGATTAGAGATGGAGGAAAAAGAGTGGGATTTAAAATAATAACCTTAGATACCAATGAAGAAACAATATTAGCC
TATGTTGGAGATGGAAAAATAAAAGTTGGTAAATATGCTGTTTTTATAGAAAATTTAGATAACGTTGGAGTTGAGGCAAT
AAAAAGGGCTTTGAAAGATGCTGATATTATAATTATAGATGAACTTGGAGCTATGGAATTTAAGAGTAGAAAGTTTTCTG
AAGTTGTTGATGAGGTTATTAAAAGTGATAAACCGTTATTAGCCACACTACACAGAAATTGGGTAAATAAATTTAAAGAT
AAAGGAGAGCTATATACTTTAACTATTGAAAATAGGGAGAAATTGTTTGAAGAAATATTAAATAAAATATTGGCAGGATT
AAAATAA

Upstream 100 bases:

>100_bases
ACTTTTGAGATTCCCGCAACTATTCCTGTTCTATCCTGCCCAATAACTGAAACTACAACTCTACTCATCTTCTCTCCTCT
TTAAATTTGATTAGTGAGTT

Downstream 100 bases:

>100_bases
TTATCTTTATCTTTCTATTCTTAAATAGCTGATAATCCCTACAACAATTGAAAATATTGCTGAAAATTTATACATATTTG
CTATTCCTAAAATATCAGCT

Product: putative NTPase

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MIYNFKHYIHQFKGCGETMRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDGGKRVGFKIITLDTNEETILA
YVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIIDELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKD
KGELYTLTIENREKLFEEILNKILAGLK

Sequences:

>Translated_188_residues
MIYNFKHYIHQFKGCGETMRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDGGKRVGFKIITLDTNEETILA
YVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIIDELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKD
KGELYTLTIENREKLFEEILNKILAGLK
>Mature_188_residues
MIYNFKHYIHQFKGCGETMRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDGGKRVGFKIITLDTNEETILA
YVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIIDELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKD
KGELYTLTIENREKLFEEILNKILAGLK

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency [H]

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI14150100, Length=187, Percent_Identity=30.4812834224599, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI85726488, Length=181, Percent_Identity=32.0441988950276, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004948 [H]

Pfam domain/function: PF03266 DUF265 [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21287; Mature: 21287

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYNFKHYIHQFKGCGETMRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHCC
GKRVGFKIITLDTNEETILAYVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIID
CCEECEEEEEEECCCCEEEEEECCCEEEECEEEEEEECCCCCCHHHHHHHHCCCCEEEEE
ELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKDKGELYTLTIENREKLFEEIL
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
NKILAGLK
HHHHHCCC
>Mature Secondary Structure
MIYNFKHYIHQFKGCGETMRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHCC
GKRVGFKIITLDTNEETILAYVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIID
CCEECEEEEEEECCCCEEEEEECCCEEEECEEEEEEECCCCCCHHHHHHHHCCCCEEEEE
ELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKDKGELYTLTIENREKLFEEIL
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
NKILAGLK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]