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The map label for this gene is cbiE

Identifier: 15669717

GI number: 15669717

Start: 1500315

End: 1500950

Strand: Direct

Name: cbiE

Synonym: MJ1522

Alternate gene names: 15669717

Gene position: 1500315-1500950 (Clockwise)

Preceding gene: 15669716

Following gene: 15669718

Centisome position: 90.11

GC content: 25.94

Gene sequence:

>636_bases
ATGATTTATATAGTTGGAATTGGACCAGGAGATAGAGAATATTTAACTTTAAAAGCAATAAAAATTGTTGAAAATGCTGA
TTTGGTTGTTGGTAGTAAAAGGGCTTTAGAATTATTTAATATAGATGAAGATAAAAAAATAACTCTAACAAAAAACTTAA
TTGGAGAGTTAAAAGAGCTAATAAAAAATGAAAATATAAAAAATAAAAAGATTGCCATATTATCAACTGGAGACCCATGT
TTTAGTGGATTATTAAAAACATTATTAAAGATTGGAGCTAAAAAAGAAGATATTGAAGCTATCTCTGGAATTTCATCTAT
ACAAATAGCAGCTGCAAAATTAAAAATCTCCTGGGAAGATTATTATATAATAACACTCCACGGAAAAGAAGAAAATAGGA
AAAAGCTTTTAAATTTGATAAAAAATCATGAGAAAGTTATCTTCTTACCAAACAATTTGAAAGAGGATGCGAAGTTTTTA
ATAAATAATGGTATAAATCCAGACACAAAAATTTGGGTTTTAGAAAATCTAACTTATGAAAATGAAAAAATTAGCTTAAA
ATCTTTAAAAGAAATAGCTAATGGAGATTTCTCTTATTTAACAGTTTGTGTTTATGAGGGAGACGAAGAGATTTGA

Upstream 100 bases:

>100_bases
ATTCTTATTTTATATTCTTATTCTGATATCTTTACCTTATCTTTTTAATTTTATTGATATTTAAAAACATAATAGTAATA
AATTATTTGAATGTGAAACT

Downstream 100 bases:

>100_bases
GTGAGGACAGTTAATGATACTTTAAGTTTTGATCAACCTTTTACTAAAAGGTTGGAGAGGAGAGGATGATTAGGGAACTA
TTATTAATAGGTGTTGGAGG

Product: cobalt-precorrin-6Y C(5)-methyltransferase

Products: S-adenosyl-L-homocysteine; Precorrin 8X; CO2

Alternate protein names: Cobalt-precorrin-6 methyltransferase; Cobalt-precorrin-6Y methylase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIYIVGIGPGDREYLTLKAIKIVENADLVVGSKRALELFNIDEDKKITLTKNLIGELKELIKNENIKNKKIAILSTGDPC
FSGLLKTLLKIGAKKEDIEAISGISSIQIAAAKLKISWEDYYIITLHGKEENRKKLLNLIKNHEKVIFLPNNLKEDAKFL
INNGINPDTKIWVLENLTYENEKISLKSLKEIANGDFSYLTVCVYEGDEEI

Sequences:

>Translated_211_residues
MIYIVGIGPGDREYLTLKAIKIVENADLVVGSKRALELFNIDEDKKITLTKNLIGELKELIKNENIKNKKIAILSTGDPC
FSGLLKTLLKIGAKKEDIEAISGISSIQIAAAKLKISWEDYYIITLHGKEENRKKLLNLIKNHEKVIFLPNNLKEDAKFL
INNGINPDTKIWVLENLTYENEKISLKSLKEIANGDFSYLTVCVYEGDEEI
>Mature_211_residues
MIYIVGIGPGDREYLTLKAIKIVENADLVVGSKRALELFNIDEDKKITLTKNLIGELKELIKNENIKNKKIAILSTGDPC
FSGLLKTLLKIGAKKEDIEAISGISSIQIAAAKLKISWEDYYIITLHGKEENRKKLLNLIKNHEKVIFLPNNLKEDAKFL
INNGINPDTKIWVLENLTYENEKISLKSLKEIANGDFSYLTVCVYEGDEEI

Specific function: Probably catalyzes the methylation of C-5 in cobalt- precorrin-6Y to form cobalt-precorrin-7W-a

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIE_METJA (Q58917)

Other databases:

- EMBL:   L77117
- PIR:   A64490
- RefSeq:   NP_248530.1
- ProteinModelPortal:   Q58917
- SMR:   Q58917
- GeneID:   1452430
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1522
- NMPDR:   fig|243232.1.peg.1567
- TIGR:   MJ1522
- HOGENOM:   HBG646061
- OMA:   KISWEDY
- ProtClustDB:   PRK05787
- BioCyc:   MJAN243232:MJ_1522-MONOMER
- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012818
- Gene3D:   G3DSA:3.40.1010.10
- Gene3D:   G3DSA:3.30.950.10
- TIGRFAMs:   TIGR02467

Pfam domain/function: PF00590 TP_methylase; SSF53790 Cor/por_Metransf

EC number: 2.1.1.132

Molecular weight: Translated: 23806; Mature: 23806

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYIVGIGPGDREYLTLKAIKIVENADLVVGSKRALELFNIDEDKKITLTKNLIGELKEL
CEEEEEECCCCCCEEEEEEEEEECCCCEEEECCCEEEEECCCCCCEEEEHHHHHHHHHHH
IKNENIKNKKIAILSTGDPCFSGLLKTLLKIGAKKEDIEAISGISSIQIAAAKLKISWED
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEEEEECC
YYIITLHGKEENRKKLLNLIKNHEKVIFLPNNLKEDAKFLINNGINPDTKIWVLENLTYE
EEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCEEC
NEKISLKSLKEIANGDFSYLTVCVYEGDEEI
CCEEHHHHHHHHHCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MIYIVGIGPGDREYLTLKAIKIVENADLVVGSKRALELFNIDEDKKITLTKNLIGELKEL
CEEEEEECCCCCCEEEEEEEEEECCCCEEEECCCEEEEECCCCCCEEEEHHHHHHHHHHH
IKNENIKNKKIAILSTGDPCFSGLLKTLLKIGAKKEDIEAISGISSIQIAAAKLKISWED
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEEEEECC
YYIITLHGKEENRKKLLNLIKNHEKVIFLPNNLKEDAKFLINNGINPDTKIWVLENLTYE
EEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCEEC
NEKISLKSLKEIANGDFSYLTVCVYEGDEEI
CCEEHHHHHHHHHCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 6Y

Specific reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087