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The map label for this gene is ycgO [C]

Identifier: 15669716

GI number: 15669716

Start: 1498900

End: 1500168

Strand: Direct

Name: ycgO [C]

Synonym: MJ1521

Alternate gene names: 15669716

Gene position: 1498900-1500168 (Clockwise)

Preceding gene: 15669714

Following gene: 15669717

Centisome position: 90.03

GC content: 33.73

Gene sequence:

>1269_bases
GTGAATATTGTATTATTTCTCGGCTATTTATCTATTCTTTTTGCTGGAGGTGCCATAATAGCAAAAATTGCTAAAAAGAT
TGGCATACCTGATATTCCTCTATTACTAATATTTGGTCTCATACTTTCTATACTAAATGTAATCCCAAAAAATATTGTTG
AAAGCTCCTTTGATTTTATTGGAAACTTTGGATTAATTATATTGTTGTTTATTGGTTCATTTGAAATGGAATGGAACATT
ATGAAGAGAGTATTGGATGTTATAATAAAACTCGATATACTGGCTTTATTAATTGTTTGGATTATATCTGGAATAGTATT
TAACTTTGTCTTTCATCTTCCAATCTTATCATTGATTGGATTGCTATTTGGGGCTATCGTTTCGGCTACTGACCCTGCTA
CATTAATACCAATATTCTCAAGCATGGATATTGATCCAGAAGTAGCAATAACCTTAGAAGCAGAGAGTGTTTTTAACGAC
CCATTAGGGATTGTTGTAACACTTATATGTTTATCAGCCCTTGGTTTAGCTAAAGCTGAGAATCCAATTCTTGAATTTTT
CTCATTAGCTGTTGGTGGGATAATATTGGGGGTTATAGCAGGCAAGTTCTATGAAATTATTATCTCAAAAATTAAGTTTG
AGGACTATATTGCTCCATTTACTTTAGGATTGGCTATTGCCTTTTGGTATTTTGCTGAGGGAATTTTCCCATCAATAACT
GGCTATGAAATTAGTGGATTTATGGCAGTGGCTATAATGGGATTATATATTGGAAACGTCATAGTGCATAAAAAAGAACA
TAAAAAAGATATGGAAAAGGTTGCAGTGTTTATGGATGAACTCTCCATATTTATCAGAATATTAATCTTCGTATTATTAG
GGGCAAGTATCTCAATCCCATTATTAGAAAAATATGCACTCCCTGCATTTTTATGTGCATTGGGTTCTATACTTTTAGCA
AGACCTGTTGGTGTTTTGATAGCTACAGCTATTCCACCAATTAGACCACTTACTGAAAGGATATATTTAGCTTTAGAAGG
GCCGAGAGGGGTAGTTCCAGCAACGTTAGCAGCAATGGTTTATACAGAGATTATGAAACATCCAAACATAGTTCCAAAAA
ATATAGCAAGCTTAATGCCTCCAACAGAACTCGCTGGAACTATATTAGTAGCAACCTTTATGACAATAATAGTCAGTGTT
GTCTTGGAAGCCTCATGGGCAAAACCATTAGCAAATATATTATTGAAAAGAAAGACCTCAACCTCCTAA

Upstream 100 bases:

>100_bases
GTTTCTATTCACATTACCACCAAAAAATTTATATGCTTTCTAAATGTAAAGTTTAGTGTCTGTATATCCAGATATTAAAA
ACTAAAAGATTGGTGGGATT

Downstream 100 bases:

>100_bases
TTTCAATTTTTAAATTTTTAATTCAAAATTTAACTTATATTTTTATATTCTTATTTTATATTCTTATTCTGATATCTTTA
CCTTATCTTTTTAATTTTAT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: MjNhaP2

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNIVLFLGYLSILFAGGAIIAKIAKKIGIPDIPLLLIFGLILSILNVIPKNIVESSFDFIGNFGLIILLFIGSFEMEWNI
MKRVLDVIIKLDILALLIVWIISGIVFNFVFHLPILSLIGLLFGAIVSATDPATLIPIFSSMDIDPEVAITLEAESVFND
PLGIVVTLICLSALGLAKAENPILEFFSLAVGGIILGVIAGKFYEIIISKIKFEDYIAPFTLGLAIAFWYFAEGIFPSIT
GYEISGFMAVAIMGLYIGNVIVHKKEHKKDMEKVAVFMDELSIFIRILIFVLLGASISIPLLEKYALPAFLCALGSILLA
RPVGVLIATAIPPIRPLTERIYLALEGPRGVVPATLAAMVYTEIMKHPNIVPKNIASLMPPTELAGTILVATFMTIIVSV
VLEASWAKPLANILLKRKTSTS

Sequences:

>Translated_422_residues
MNIVLFLGYLSILFAGGAIIAKIAKKIGIPDIPLLLIFGLILSILNVIPKNIVESSFDFIGNFGLIILLFIGSFEMEWNI
MKRVLDVIIKLDILALLIVWIISGIVFNFVFHLPILSLIGLLFGAIVSATDPATLIPIFSSMDIDPEVAITLEAESVFND
PLGIVVTLICLSALGLAKAENPILEFFSLAVGGIILGVIAGKFYEIIISKIKFEDYIAPFTLGLAIAFWYFAEGIFPSIT
GYEISGFMAVAIMGLYIGNVIVHKKEHKKDMEKVAVFMDELSIFIRILIFVLLGASISIPLLEKYALPAFLCALGSILLA
RPVGVLIATAIPPIRPLTERIYLALEGPRGVVPATLAAMVYTEIMKHPNIVPKNIASLMPPTELAGTILVATFMTIIVSV
VLEASWAKPLANILLKRKTSTS
>Mature_422_residues
MNIVLFLGYLSILFAGGAIIAKIAKKIGIPDIPLLLIFGLILSILNVIPKNIVESSFDFIGNFGLIILLFIGSFEMEWNI
MKRVLDVIIKLDILALLIVWIISGIVFNFVFHLPILSLIGLLFGAIVSATDPATLIPIFSSMDIDPEVAITLEAESVFND
PLGIVVTLICLSALGLAKAENPILEFFSLAVGGIILGVIAGKFYEIIISKIKFEDYIAPFTLGLAIAFWYFAEGIFPSIT
GYEISGFMAVAIMGLYIGNVIVHKKEHKKDMEKVAVFMDELSIFIRILIFVLLGASISIPLLEKYALPAFLCALGSILLA
RPVGVLIATAIPPIRPLTERIYLALEGPRGVVPATLAAMVYTEIMKHPNIVPKNIASLMPPTELAGTILVATFMTIIVSV
VLEASWAKPLANILLKRKTSTS

Specific function: This is probably a Na(+)/H(+) antiporter

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

Homologues:

Organism=Escherichia coli, GI87081854, Length=399, Percent_Identity=26.5664160401003, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAH2_METJA (Q58916)

Other databases:

- EMBL:   L77117
- PIR:   H64489
- RefSeq:   NP_248529.1
- ProteinModelPortal:   Q58916
- GeneID:   1452429
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1521
- NMPDR:   fig|243232.1.peg.1566
- TIGR:   MJ1521
- HOGENOM:   HBG726978
- OMA:   ISGFMAV
- ProtClustDB:   CLSK876053
- BioCyc:   MJAN243232:MJ_1521-MONOMER
- InterPro:   IPR006153

Pfam domain/function: PF00999 Na_H_Exchanger

EC number: NA

Molecular weight: Translated: 45810; Mature: 45810

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xea17090)-; HASH(0xed00c70)-; HASH(0xdd5d370)-; HASH(0xe9033bc)-; HASH(0xdd5d190)-; HASH(0xedbb970)-; HASH(0xdd5d748)-; HASH(0xb549e74)-; HASH(0xb4b05a0)-; HASH(0xdd5df1c)-; HASH(0xd332f80)-; HASH(0xb822fd8)-; HASH(0xed6d6a4)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVLFLGYLSILFAGGAIIAKIAKKIGIPDIPLLLIFGLILSILNVIPKNIVESSFDFI
CCEEHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNFGLIILLFIGSFEMEWNIMKRVLDVIIKLDILALLIVWIISGIVFNFVFHLPILSLIG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLFGAIVSATDPATLIPIFSSMDIDPEVAITLEAESVFNDPLGIVVTLICLSALGLAKAE
HHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCC
NPILEFFSLAVGGIILGVIAGKFYEIIISKIKFEDYIAPFTLGLAIAFWYFAEGIFPSIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GYEISGFMAVAIMGLYIGNVIVHKKEHKKDMEKVAVFMDELSIFIRILIFVLLGASISIP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LLEKYALPAFLCALGSILLARPVGVLIATAIPPIRPLTERIYLALEGPRGVVPATLAAMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCCCHHHHHHHHH
YTEIMKHPNIVPKNIASLMPPTELAGTILVATFMTIIVSVVLEASWAKPLANILLKRKTS
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TS
CH
>Mature Secondary Structure
MNIVLFLGYLSILFAGGAIIAKIAKKIGIPDIPLLLIFGLILSILNVIPKNIVESSFDFI
CCEEHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNFGLIILLFIGSFEMEWNIMKRVLDVIIKLDILALLIVWIISGIVFNFVFHLPILSLIG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLFGAIVSATDPATLIPIFSSMDIDPEVAITLEAESVFNDPLGIVVTLICLSALGLAKAE
HHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCC
NPILEFFSLAVGGIILGVIAGKFYEIIISKIKFEDYIAPFTLGLAIAFWYFAEGIFPSIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GYEISGFMAVAIMGLYIGNVIVHKKEHKKDMEKVAVFMDELSIFIRILIFVLLGASISIP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LLEKYALPAFLCALGSILLARPVGVLIATAIPPIRPLTERIYLALEGPRGVVPATLAAMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCCCHHHHHHHHH
YTEIMKHPNIVPKNIASLMPPTELAGTILVATFMTIIVSVVLEASWAKPLANILLKRKTS
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TS
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087