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The map label for this gene is argE [C]

Identifier: 15669691

GI number: 15669691

Start: 1469706

End: 1470746

Strand: Direct

Name: argE [C]

Synonym: MJ1497

Alternate gene names: 15669691

Gene position: 1469706-1470746 (Clockwise)

Preceding gene: 15669690

Following gene: 15669692

Centisome position: 88.27

GC content: 27.09

Gene sequence:

>1041_bases
ATGATAATTATGGATTATTTAAAAATCTTAGAGGATTTGGTGAAAATTAGGACGGATAATAGAATTGGTGTTAAAAAGGC
ATTTAAATATTTATCTAATCTTTTCAATAACTTAGGAATAAAAAATACTATCATTGAAGGATGCTTTGTAGCATATAAAG
AAAAAGAAAACTTTGATTTGATATTAAATTCACATATAGACACTGTAAAGATTCAATCAAATTTTAAAAAAGATGATAAC
AATTTTTATGGGACTGGAGTTATAGATGCTAAAGGGAATGTGGTTTTAATGATTCATGCTTTTTTAAATAGCAATAACTC
TCTATTAGTTATATCTCCTGATGAAGAAACAGAATCAAATGGTATTTACAATTTTTGCCAATATTTAAGAAATAAAAATA
AAATTCAAAGAGGTATTAAATGCATAGTTGGAGAGCCTACTGACTTAAATGTTTGTATTGGACATAAAGGAAGATTTGAG
TATATTGTTGAAAGTTTTGGGGAGGCGAGGCATGCCTCATCTCAAGGCCTAAATCCAATAGAAATCTTAAGCAGAGTTAT
TTTAGATTTAAAAAATCTTCCTTTGGAAAAGATTAAGGTTGATAAAATCTACAGTTCTTCAATAACTCCAACCATAATAA
AAGGAGGAATTCAAAGCAATATCATTCCAGATTATGCTTATGTCTTATTTGATGTTAGAAGTGTTGAAAAAGATATAATA
AAAAAGATAGACGACTTTTTATCTCAAAAAAATTATTCAAAGCATATAAAAAGCTCATTAAATCCTGAAAGACATTATGC
TAATTTCTACATGCTTGAAAATAAAGAGTTAATAAATAAGTTGTCTAAGCACTTTAAAATATCATTTTTTAATGCTACTT
GCGAAGCATATTACTTCAACAAATTTTTAAAGGCAGATACTATTATTTATGGTGTTGGCAAATTAGAGCTTGCCCATTCT
AAAGAAGAATATTTAAACTTAAATGATTTTGATAGGGGAATTAAAGAAGTAGAGAAGCTTGCAGAATTGATGATAGAATA
A

Upstream 100 bases:

>100_bases
AAACCTACAAATGTAAAAATTACTCAACAGCAATGCTTGAATTTAAGTGTAGTGATATTGATTTAAATGAAATTATTGGA
GAAAAAGTAGAATTTATGAG

Downstream 100 bases:

>100_bases
ATAATGATGGGGATTAAAAATGGAGATAAATAAAATCTACTGTATGGATTGTTTAGAGGGAATGAAACAGTTAAAAGATA
AGACAGTTGATGTTGTTGTT

Product: acetylornithine deacetylase ArgE

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIIMDYLKILEDLVKIRTDNRIGVKKAFKYLSNLFNNLGIKNTIIEGCFVAYKEKENFDLILNSHIDTVKIQSNFKKDDN
NFYGTGVIDAKGNVVLMIHAFLNSNNSLLVISPDEETESNGIYNFCQYLRNKNKIQRGIKCIVGEPTDLNVCIGHKGRFE
YIVESFGEARHASSQGLNPIEILSRVILDLKNLPLEKIKVDKIYSSSITPTIIKGGIQSNIIPDYAYVLFDVRSVEKDII
KKIDDFLSQKNYSKHIKSSLNPERHYANFYMLENKELINKLSKHFKISFFNATCEAYYFNKFLKADTIIYGVGKLELAHS
KEEYLNLNDFDRGIKEVEKLAELMIE

Sequences:

>Translated_346_residues
MIIMDYLKILEDLVKIRTDNRIGVKKAFKYLSNLFNNLGIKNTIIEGCFVAYKEKENFDLILNSHIDTVKIQSNFKKDDN
NFYGTGVIDAKGNVVLMIHAFLNSNNSLLVISPDEETESNGIYNFCQYLRNKNKIQRGIKCIVGEPTDLNVCIGHKGRFE
YIVESFGEARHASSQGLNPIEILSRVILDLKNLPLEKIKVDKIYSSSITPTIIKGGIQSNIIPDYAYVLFDVRSVEKDII
KKIDDFLSQKNYSKHIKSSLNPERHYANFYMLENKELINKLSKHFKISFFNATCEAYYFNKFLKADTIIYGVGKLELAHS
KEEYLNLNDFDRGIKEVEKLAELMIE
>Mature_346_residues
MIIMDYLKILEDLVKIRTDNRIGVKKAFKYLSNLFNNLGIKNTIIEGCFVAYKEKENFDLILNSHIDTVKIQSNFKKDDN
NFYGTGVIDAKGNVVLMIHAFLNSNNSLLVISPDEETESNGIYNFCQYLRNKNKIQRGIKCIVGEPTDLNVCIGHKGRFE
YIVESFGEARHASSQGLNPIEILSRVILDLKNLPLEKIKVDKIYSSSITPTIIKGGIQSNIIPDYAYVLFDVRSVEKDII
KKIDDFLSQKNYSKHIKSSLNPERHYANFYMLENKELINKLSKHFKISFFNATCEAYYFNKFLKADTIIYGVGKLELAHS
KEEYLNLNDFDRGIKEVEKLAELMIE

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1497_METJA (Q58892)

Other databases:

- EMBL:   L77117
- PIR:   H64486
- RefSeq:   NP_248504.1
- ProteinModelPortal:   Q58892
- GeneID:   1452404
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1497
- NMPDR:   fig|243232.1.peg.1541
- TIGR:   MJ1497
- OMA:   ISFFNAT
- ProtClustDB:   CLSK2517738
- BioCyc:   MJAN243232:MJ_1497-MONOMER
- InterPro:   IPR002933
- InterPro:   IPR011650

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: 3.5.1.16

Molecular weight: Translated: 39800; Mature: 39800

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: ACT_SITE 67-67 ACT_SITE 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIMDYLKILEDLVKIRTDNRIGVKKAFKYLSNLFNNLGIKNTIIEGCFVAYKEKENFDL
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCEE
ILNSHIDTVKIQSNFKKDDNNFYGTGVIDAKGNVVLMIHAFLNSNNSLLVISPDEETESN
EEECCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEECCCCCCCCC
GIYNFCQYLRNKNKIQRGIKCIVGEPTDLNVCIGHKGRFEYIVESFGEARHASSQGLNPI
CHHHHHHHHHCHHHHHHCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHH
EILSRVILDLKNLPLEKIKVDKIYSSSITPTIIKGGIQSNIIPDYAYVLFDVRSVEKDII
HHHHHHHHHHHCCCHHHEEHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KKIDDFLSQKNYSKHIKSSLNPERHYANFYMLENKELINKLSKHFKISFFNATCEAYYFN
HHHHHHHHCCCHHHHHHHCCCCCHHHEEEEEEECHHHHHHHHHHEEEEEECCHHHHHHHH
KFLKADTIIYGVGKLELAHSKEEYLNLNDFDRGIKEVEKLAELMIE
HHHHHCEEEEECCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIMDYLKILEDLVKIRTDNRIGVKKAFKYLSNLFNNLGIKNTIIEGCFVAYKEKENFDL
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCEE
ILNSHIDTVKIQSNFKKDDNNFYGTGVIDAKGNVVLMIHAFLNSNNSLLVISPDEETESN
EEECCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEECCCCCCCCC
GIYNFCQYLRNKNKIQRGIKCIVGEPTDLNVCIGHKGRFEYIVESFGEARHASSQGLNPI
CHHHHHHHHHCHHHHHHCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHH
EILSRVILDLKNLPLEKIKVDKIYSSSITPTIIKGGIQSNIIPDYAYVLFDVRSVEKDII
HHHHHHHHHHHCCCHHHEEHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KKIDDFLSQKNYSKHIKSSLNPERHYANFYMLENKELINKLSKHFKISFFNATCEAYYFN
HHHHHHHHCCCHHHHHHHCCCCCHHHEEEEEEECHHHHHHHHHHEEEEEECCHHHHHHHH
KFLKADTIIYGVGKLELAHSKEEYLNLNDFDRGIKEVEKLAELMIE
HHHHHCEEEEECCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087