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The map label for this gene is 15669575

Identifier: 15669575

GI number: 15669575

Start: 1333197

End: 1333736

Strand: Reverse

Name: 15669575

Synonym: MJ1385

Alternate gene names: NA

Gene position: 1333736-1333197 (Counterclockwise)

Preceding gene: 15669577

Following gene: 15669574

Centisome position: 80.11

GC content: 33.15

Gene sequence:

>540_bases
ATGGTTGTTGAGGTTTTAAGATTAGGACATAGAGGAGACAGAGATAAGAGGATATCAACCCACGTAGCTTTAACCGCAAG
AGCCTTAGGAGCAGATAAAATAATTTTTACAACTGAAGATGAACACGTTGAAAATAGTGTTAAAAAAGTTGTAGAGAGTT
GGGGAGGAAACTTTGAGTTTGTTGTTGAAAAACATTGGAGAAAATATATTAGAGAATTTAAAAAAAGAGGGATTGTAGTT
CATCTAACAATGTATGGGGCTAATATAAATGAGATAATGCCAGAGATTAGAGAAATAAGCAGAGATAAAGATATATTAGT
TATAGTTGGGGCTGAAAAAGTGCCAAAGGAGGTTTATGAATTGGCTGATTATAATGTATCTGTTGGTAACCAACCACACT
CCGAAGTTGCTGCTTTGGCAATCTTTTTAGATAGATTGTTTGAGGGTAAAACACTTTATAGAGATTTTGAAGATGCAAAG
ATAAAGATAGTCCCATCAAAAGATGGAAAAGTAGTTATAAGAGAAAAGCAAAATAAATAA

Upstream 100 bases:

>100_bases
ATATGGATGTAGAGATTTGGAAAGTTGTTTTAACAACTGCATCATATATTTTCAAATATTTATGACTTAGAGTATAAATA
ATTTATGATGAGGGATTATT

Downstream 100 bases:

>100_bases
TATCAAAATATATTGGGGGATACTATGGAAATCCAACTTCCAGATATAGAGGAAATAAAGTTAGAGGATGTTTTGATAAA
GAGGAGGTCAGTTAGGGAAT

Product: tRNA 2'-O-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEFVVEKHWRKYIREFKKRGIVV
HLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYELADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAK
IKIVPSKDGKVVIREKQNK

Sequences:

>Translated_179_residues
MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEFVVEKHWRKYIREFKKRGIVV
HLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYELADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAK
IKIVPSKDGKVVIREKQNK
>Mature_179_residues
MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEFVVEKHWRKYIREFKKRGIVV
HLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYELADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAK
IKIVPSKDGKVVIREKQNK

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRM56_METJA (Q58780)

Other databases:

- EMBL:   L77117
- PIR:   H64472
- RefSeq:   NP_248388.1
- ProteinModelPortal:   Q58780
- SMR:   Q58780
- GeneID:   1452288
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1385
- NMPDR:   fig|243232.1.peg.1425
- TIGR:   MJ1385
- HOGENOM:   HBG297370
- OMA:   GHRPERD
- ProtClustDB:   PRK03958
- BioCyc:   MetaCyc:MONOMER-2005
- BioCyc:   MJAN243232:MJ_1385-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00077
- InterPro:   IPR002845
- PIRSF:   PIRSF016123
- ProDom:   PD016584

Pfam domain/function: PF01994 DUF127

EC number: NA

Molecular weight: Translated: 20573; Mature: 20573

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: BINDING 82-82

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEF
CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEE
VVEKHWRKYIREFKKRGIVVHLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYE
EHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAKIKIVPSKDGKVVIREKQNK
HHCCCEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEF
CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEE
VVEKHWRKYIREFKKRGIVVHLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYE
EHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAKIKIVPSKDGKVVIREKQNK
HHCCCEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087