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The map label for this gene is 15669436

Identifier: 15669436

GI number: 15669436

Start: 1192970

End: 1193731

Strand: Direct

Name: 15669436

Synonym: MJ1250

Alternate gene names: NA

Gene position: 1192970-1193731 (Clockwise)

Preceding gene: 15669435

Following gene: 15669438

Centisome position: 71.65

GC content: 34.12

Gene sequence:

>762_bases
ATGAAGATAAAGATTGGCAAAGTTGAAAAAAGATTAAATCAAATTATTGAAGAGGAAGGAGCTGTCTATTTAACTCTATT
AGACCCAGAAGAAGAAAATATTGAAGAGATAGCTGAAAATGTTAAGGATTATGCAGATGCAATAATGGTTGGAGGAAGTA
TTGGAATTGTTAATTTAGATGAAACAGTTAAAAAAATAAAAAAGATAACTAAGCTCCCAATAATTCTATTCCCTGGAAAT
GTTGATGGATTGTCAAGATATGCTGACGCTGTGTTTTACATGAGCCTAATGAACTCAGCAAACACTTATTGGGTTGTAAC
AGCCCCAACTTTAGGGGCGATAACAATTTTAAAATATAATTTAGAGCCAATTCCAATGGCTTATCTCTGCATAGAACCAG
CAAAAAAAACAGCCGTTGGTTATGTTGGGGAGATTAGAGAGATACCTCAAAACAAACCAAAAATAACTGCAATGTATTGT
TTATCTGCAAAGTTCTTTGGAATGAGATGGGCTTATTTAGAGGCTGGTAGTGGGGCATCTTACCCAGTAAACAATGAGAC
TATAGCCTTATCAAAAAAACTCTCTGGAATTAATATAATTGTTGGTGGAGGAATTAGAAAGCCAGAGATTGCCTATGAGA
AAGTTTTAGCTGGAGCTGATGCTATAGTTACTGGTAATTTGTTGGAAGAGAATCCTAAAGCTGTTGAGATGATGTATGAT
GCTATTAAAAAAGCTGGAAAAGAGAAATTGAAAAATAAGTAA

Upstream 100 bases:

>100_bases
TGGGAGGAACTCGATATAAAAGAAGATGAAGGCTATTTAAAGATTAAGATAAAATATTATCCAAAGGAAATTATGTATAA
AAAATAAATCCTGTGAGATT

Downstream 100 bases:

>100_bases
AAGAATTTAAACGGTTATCTATTTTTTACCTTTTTCGCAACAAATCCAATGTATGATGCAAAGTTTTTTAAAAAGCTTTT
GTAAATAAATTTATCTAATG

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKIKIGKVEKRLNQIIEEEGAVYLTLLDPEEENIEEIAENVKDYADAIMVGGSIGIVNLDETVKKIKKITKLPIILFPGN
VDGLSRYADAVFYMSLMNSANTYWVVTAPTLGAITILKYNLEPIPMAYLCIEPAKKTAVGYVGEIREIPQNKPKITAMYC
LSAKFFGMRWAYLEAGSGASYPVNNETIALSKKLSGINIIVGGGIRKPEIAYEKVLAGADAIVTGNLLEENPKAVEMMYD
AIKKAGKEKLKNK

Sequences:

>Translated_253_residues
MKIKIGKVEKRLNQIIEEEGAVYLTLLDPEEENIEEIAENVKDYADAIMVGGSIGIVNLDETVKKIKKITKLPIILFPGN
VDGLSRYADAVFYMSLMNSANTYWVVTAPTLGAITILKYNLEPIPMAYLCIEPAKKTAVGYVGEIREIPQNKPKITAMYC
LSAKFFGMRWAYLEAGSGASYPVNNETIALSKKLSGINIIVGGGIRKPEIAYEKVLAGADAIVTGNLLEENPKAVEMMYD
AIKKAGKEKLKNK
>Mature_253_residues
MKIKIGKVEKRLNQIIEEEGAVYLTLLDPEEENIEEIAENVKDYADAIMVGGSIGIVNLDETVKKIKKITKLPIILFPGN
VDGLSRYADAVFYMSLMNSANTYWVVTAPTLGAITILKYNLEPIPMAYLCIEPAKKTAVGYVGEIREIPQNKPKITAMYC
LSAKFFGMRWAYLEAGSGASYPVNNETIALSKKLSGINIIVGGGIRKPEIAYEKVLAGADAIVTGNLLEENPKAVEMMYD
AIKKAGKEKLKNK

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_METJA (Q58647)

Other databases:

- EMBL:   L77117
- PIR:   A64456
- RefSeq:   NP_248246.1
- ProteinModelPortal:   Q58647
- SMR:   Q58647
- GeneID:   1452148
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1250
- NMPDR:   fig|243232.1.peg.1283
- TIGR:   MJ1250
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- BioCyc:   MJAN243232:MJ_1250-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 27797; Mature: 27797

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: BINDING 204-204

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKIGKVEKRLNQIIEEEGAVYLTLLDPEEENIEEIAENVKDYADAIMVGGSIGIVNLD
CEEECHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCCEEEEEHH
ETVKKIKKITKLPIILFPGNVDGLSRYADAVFYMSLMNSANTYWVVTAPTLGAITILKYN
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEC
LEPIPMAYLCIEPAKKTAVGYVGEIREIPQNKPKITAMYCLSAKFFGMRWAYLEAGSGAS
CCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCEEEEEEECCCCCC
YPVNNETIALSKKLSGINIIVGGGIRKPEIAYEKVLAGADAIVTGNLLEENPKAVEMMYD
CCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCEEECCHHHCCCHHHHHHHH
AIKKAGKEKLKNK
HHHHHHHHHHCCC
>Mature Secondary Structure
MKIKIGKVEKRLNQIIEEEGAVYLTLLDPEEENIEEIAENVKDYADAIMVGGSIGIVNLD
CEEECHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCCEEEEEHH
ETVKKIKKITKLPIILFPGNVDGLSRYADAVFYMSLMNSANTYWVVTAPTLGAITILKYN
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEC
LEPIPMAYLCIEPAKKTAVGYVGEIREIPQNKPKITAMYCLSAKFFGMRWAYLEAGSGAS
CCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCEEEEEEECCCCCC
YPVNNETIALSKKLSGINIIVGGGIRKPEIAYEKVLAGADAIVTGNLLEENPKAVEMMYD
CCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCEEECCHHHCCCHHHHHHHH
AIKKAGKEKLKNK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087