BacMap

Definition	Methanocaldococcus jannaschii DSM 2661 chromosome, complete genome.
Accession	NC_000909
Length	1,664,970

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The map label for this gene is psmB [H]

Identifier: 15669422

GI number: 15669422

Start: 1182388

End: 1183062

Strand: Reverse

Name: psmB [H]

Synonym: MJ1237

Alternate gene names: 15669422

Gene position: 1183062-1182388 (Counterclockwise)

Preceding gene: 15669423

Following gene: 15669421

Centisome position: 71.06

GC content: 34.07

Gene sequence:

>675_bases
ATGGATGTAATGAAAGGAACAACAACCGTTGGTTTAATTTGTGACGATGCAGTAATTTTAGCGACAGATAAAAGGGCATC
ATTAGGTAATTTAGTAGCTGACAAAGAAGCAAAAAAATTATATAAGATAGATGATTACATAGCGATGACCATTGCGGGAA
GTGTTGGAGACGCTCAAGCGATAGTTAGGTTATTAATTGCTGAGGCAAAACTATACAAAATGAGAACTGGGAGAAATATC
CCTCCATTGGCATGTGCTACCCTATTGAGTAATATATTGCATTCAAGTAGAATGTTCCCTTTTTTAACTCAGATAATTAT
TGGTGGGTATGATTTATTGGAAGGAGCTAAATTATTTTCATTAGACCCATTAGGAGGAATGAACGAAGAAAAAACTTTTA
CAGCTACTGGTTCTGGTTCTCCAATTGCCTATGGGGTTTTAGAAGCTGGATATGATAGAGATATGTCAGTTGAAGAAGGG
ATAAAATTAGCCCTAAATGCATTAAAATCAGCAATGGAAAGAGACACATTTTCAGGAAATGGTATATCATTAGCTGTTAT
AACAAAAGATGGTGTTAAGATATTTGAGGATGAAGAGATTGAAAAAATCTTAGATAGTATGAAAGCTAAACCTAAGAAAA
AAACCACAAAAAGAAGTAGAAGAAAGAGCAAATAA

Upstream 100 bases:

>100_bases
TAAGATTTATGAACAAAATAAAATTTTTATTTATTGAAATATTATTAGAAAGCTATTAAAAGTGAGAAATAGGAAATAGG
TAATTATTTAAGGTGAAAGA

Downstream 100 bases:

>100_bases
AATAAATTAGATATGGAATTGTTAGAATTAAGCTAAAGGCTAATAAGTTTAATATAAGATTAAAAATTTTAAGAAAAATA
TAGATAAAAATCTATAAAAT

Product: proteasome subunit beta PsmB

Products: NA

Alternate protein names: 20S proteasome beta subunit; Proteasome core protein PsmB [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRTGRNI
PPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEG
IKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK

Sequences:

>Translated_224_residues
MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRTGRNI
PPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEG
IKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK
>Mature_224_residues
MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRTGRNI
PPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEG
IKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family [H]

Homologues:

Organism=Homo sapiens, GI73747875, Length=208, Percent_Identity=31.7307692307692, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI4758970, Length=208, Percent_Identity=31.7307692307692, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI4506201, Length=191, Percent_Identity=32.9842931937173, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI23110925, Length=194, Percent_Identity=35.0515463917526, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4506193, Length=200, Percent_Identity=29.5, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4506205, Length=208, Percent_Identity=31.7307692307692, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI4506191, Length=194, Percent_Identity=34.020618556701, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI153791216, Length=229, Percent_Identity=31.0043668122271, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4506203, Length=220, Percent_Identity=28.6363636363636, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI22538465, Length=182, Percent_Identity=25.8241758241758, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI195539356, Length=141, Percent_Identity=32.6241134751773, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI156713442, Length=206, Percent_Identity=24.7572815533981, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4506185, Length=206, Percent_Identity=24.7572815533981, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4506183, Length=127, Percent_Identity=27.5590551181102, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI68303563, Length=206, Percent_Identity=28.1553398058252, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4506189, Length=210, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4506195, Length=189, Percent_Identity=26.4550264550265, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535357, Length=189, Percent_Identity=27.5132275132275, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508499, Length=195, Percent_Identity=32.3076923076923, Blast_Score=90, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17508495, Length=191, Percent_Identity=31.413612565445, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541700, Length=193, Percent_Identity=25.9067357512953, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554384, Length=194, Percent_Identity=26.8041237113402, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17508493, Length=183, Percent_Identity=30.6010928961749, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508491, Length=213, Percent_Identity=28.169014084507, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325360, Length=206, Percent_Identity=29.6116504854369, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324731, Length=186, Percent_Identity=30.6451612903226, Blast_Score=88, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6322459, Length=204, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321574, Length=207, Percent_Identity=28.9855072463768, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319430, Length=207, Percent_Identity=26.5700483091787, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320849, Length=193, Percent_Identity=26.4248704663212, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321692, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323547, Length=190, Percent_Identity=27.8947368421053, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130281, Length=209, Percent_Identity=31.1004784688995, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24639979, Length=202, Percent_Identity=32.1782178217822, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653999, Length=199, Percent_Identity=31.1557788944724, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355573, Length=187, Percent_Identity=32.620320855615, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24652553, Length=187, Percent_Identity=32.620320855615, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573221, Length=189, Percent_Identity=33.8624338624339, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24584895, Length=215, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24664391, Length=195, Percent_Identity=31.7948717948718, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17737605, Length=202, Percent_Identity=26.2376237623762, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355629, Length=190, Percent_Identity=23.1578947368421, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281360341, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586406, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586400, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586402, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581176, Length=211, Percent_Identity=25.1184834123223, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922898, Length=144, Percent_Identity=28.4722222222222, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17933602, Length=172, Percent_Identity=27.906976744186, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 24286; Mature: 24286

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00854 PROTEASOME_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA
CCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHH
IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCEEE
LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN
ECCCCCCCCCCEEEECCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK
CEEEEEEECCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA
CCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHH
IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCEEE
LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN
ECCCCCCCCCCEEEECCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK
CEEEEEEECCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA