Click here to switch to the map view.

The map label for this gene is 15669421

Identifier: 15669421

GI number: 15669421

Start: 1180244

End: 1182148

Strand: Reverse

Name: 15669421

Synonym: MJ1236

Alternate gene names: NA

Gene position: 1182148-1180244 (Counterclockwise)

Preceding gene: 15669422

Following gene: 15669420

Centisome position: 71.0

GC content: 35.8

Gene sequence:

>1905_bases
TTGTCAGCAGAGGAAGTTTTAGAAAATATAAGAAAAGAGATAATAAAAAAATCACCAAAAGAGGCGAAAATAGTTGATGT
TCAGTTTGAGGGGCCTGAAGTCGTTGTCTATGTAAAAAATCCAGAAATTTTCACAAATGAAATTATTAAAAGCCTTGCTA
AGGATTTGAGGAAAAGAATTTCCATAAGACCAGACCCATCTGTTTTAGTTGAGCCAGAAATAGCTAAACAGAAAATTTTA
GAAATTGTCCCTGAAGAGGCAGAAATAACTAACTTTGTTTTTGATGCAAACACTGGGGAAGTCATAATAGAATCAAAGAA
ACCTGGATTGGTTATAGGTAAAGAAGGAAAAACACTGGAAATGATTAAAAAAGCAATAAGATGGGCACCTAAACCAGTAA
GAACTCCACCAATACAATCAGAGACAATAAAAGCAATTAGGGCCACACTTTATAGGGAGAGACATGAGGTTAAAGAAATT
TTAAGAAGAATTGGAAGGAGAATACATAGAGATATAGTTGTTAGAGGAGATTATTGGATAAGAGTATCTTTCTTAGGAGG
AGCAAGAGAAGTTGGTAGGTCTTGCTTATATGTTCAAACACCAGACACAAGGGTATTAATTGATTGTGGTATCAATGTAG
CATGTGAAGATAAGGCATTTCCTCACTTTGATGCTCCAGAATTCTCAATTGAAGATTTAGATGCTGTTATAGTTACTCAT
GCTCACTTAGATCACTGTGGTTTTATTCCCGGTTTGTTTAGATATGGTTATGACGGTCCTGTTTACTGCACAAGACCAAC
AAGGGATTTAATGACTTTATTGCAAAAAGATTATTTAGAGATAGCTAAAAAAGAGGGTAAAGAAGTTCCTTACACCTCAA
AAGATATAAAAACATGTGTTAAGCACACAATACCAATTGATTATGGAGTTACAACAGACATAAGCCCAACAATAAAATTA
ACCCTACATAATGCTGGACACGTTTTAGGTTCTGCTATTGCCCATTTACATATAGGAGAGGGGTTGTATAACTTAGCCTA
TACTGGAGACATCAAGTTTGAGACATCAAGGCTGTTAGAGCCGGCTGTTTGCCAATTCCCAAGATTAGAAACATTGATAA
TTGAATCTACTTATGGGGCTTATGATGATGTTCTGCCAGAGAGGGAAGAGGCAGAGAGAGAGCTTTTGAGGGTTGTTAGT
GAAACAACAGATAGAGGAGGAAAGGTTTTAATTCCAGTATTTGGAGTTGGAAGAGCTCAGGAGTTAATGCTTGTTTTAGA
AGAAGGATACAATCAAGGCATATTTAACGCTCCTGTCTATTTAGACGGAATGATTTGGGAAGCTACTGCTATACATACTG
CATATCCAGAGTATTTATCAAAAGAAATGAGGCAGAAGATATTCCACGAAGGAGATAATCCATTCTTATCTGAAGTATTT
AAGAGGGTTGGAAGCACTAATGAAAGAAGGAAAGTTATTGATAGTGATGAACCATGTGTAATCTTAGCAACATCTGGAAT
GCTTACTGGAGGGCCGAGTGTTGAGTATCTAAAACACTTAGCTCCAGATGAGAAAAATGCAATAATATTTGTTGGTTATC
AAGCAGAGGGAACTTTGGGTAGAAAGGTTCAGAGCGGTTGGAAAGAGATTCCAATCATTACAAGAAATGGAAAGACAAAA
TCAATTCCAATAAATCTACAGGTTTATACAATTGAAGGATTTTCAGGACATAGTGATAGAAAGCAGTTAATTAAGTATAT
CAGAAGATTGAAGCCTTCACCAGAGAAGATAATTATGGTTCATGGAGAAGAGAGTAAGTGCTTAGATTTTGCAGATACAG
TTAGAAGATTGTTCAAAAAACAAACTTATGTGCCAATGAACTTGGATGCTATAAGGGTTAAGTAA

Upstream 100 bases:

>100_bases
TTTAATTTTAACATTTTTTCATAAACAATTACAAAATATTATCAAAATTTTCAATTTAAAACACGGCAGAGATTTTTAAA
AGTTAAGGAGGAGGATTATT

Downstream 100 bases:

>100_bases
TTAATTTTATGTGCCTTTCAAAACTGTTTAATTCTATTTGTTAAATTTTTTCAAAATATTAAAATCAAATCAATTCGGAA
TGAAAATTTATTAATTCATT

Product: putative mRNA 3'-end processing factor 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSAEEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTNEIIKSLAKDLRKRISIRPDPSVLVEPEIAKQKIL
EIVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLEMIKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEI
LRRIGRRIHRDIVVRGDYWIRVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFSIEDLDAVIVTH
AHLDHCGFIPGLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDIKTCVKHTIPIDYGVTTDISPTIKL
TLHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKFETSRLLEPAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVS
ETTDRGGKVLIPVFGVGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDNPFLSEVF
KRVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGYQAEGTLGRKVQSGWKEIPIITRNGKTK
SIPINLQVYTIEGFSGHSDRKQLIKYIRRLKPSPEKIIMVHGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK

Sequences:

>Translated_634_residues
MSAEEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTNEIIKSLAKDLRKRISIRPDPSVLVEPEIAKQKIL
EIVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLEMIKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEI
LRRIGRRIHRDIVVRGDYWIRVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFSIEDLDAVIVTH
AHLDHCGFIPGLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDIKTCVKHTIPIDYGVTTDISPTIKL
TLHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKFETSRLLEPAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVS
ETTDRGGKVLIPVFGVGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDNPFLSEVF
KRVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGYQAEGTLGRKVQSGWKEIPIITRNGKTK
SIPINLQVYTIEGFSGHSDRKQLIKYIRRLKPSPEKIIMVHGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK
>Mature_633_residues
SAEEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTNEIIKSLAKDLRKRISIRPDPSVLVEPEIAKQKILE
IVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLEMIKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEIL
RRIGRRIHRDIVVRGDYWIRVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFSIEDLDAVIVTHA
HLDHCGFIPGLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDIKTCVKHTIPIDYGVTTDISPTIKLT
LHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKFETSRLLEPAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVSE
TTDRGGKVLIPVFGVGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDNPFLSEVFK
RVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGYQAEGTLGRKVQSGWKEIPIITRNGKTKS
IPINLQVYTIEGFSGHSDRKQLIKYIRRLKPSPEKIIMVHGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI33300633, Length=459, Percent_Identity=33.1154684095861, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI7706427, Length=427, Percent_Identity=31.3817330210773, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI34101288, Length=372, Percent_Identity=23.1182795698925, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32564696, Length=462, Percent_Identity=32.2510822510823, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI32566029, Length=444, Percent_Identity=31.981981981982, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17559452, Length=379, Percent_Identity=23.4828496042216, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323307, Length=440, Percent_Identity=32.9545454545455, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21358523, Length=455, Percent_Identity=32.0879120879121, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24648013, Length=466, Percent_Identity=30.68669527897, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI21358013, Length=376, Percent_Identity=23.936170212766, Blast_Score=93, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1236_METJA (Q58633)

Other databases:

- EMBL:   L77117
- PIR:   C64454
- RefSeq:   NP_248231.1
- ProteinModelPortal:   Q58633
- SMR:   Q58633
- GeneID:   1452132
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1236
- NMPDR:   fig|243232.1.peg.1268
- TIGR:   MJ1236
- HOGENOM:   HBG297590
- OMA:   VEFEGPE
- ProtClustDB:   CLSK862608
- BioCyc:   MJAN243232:MJ_1236-MONOMER
- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108
- SMART:   SM00322
- SMART:   SM00849
- TIGRFAMs:   TIGR03675

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL

EC number: NA

Molecular weight: Translated: 71762; Mature: 71631

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTNEIIKSLAKDLRKRI
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
SIRPDPSVLVEPEIAKQKILEIVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLE
CCCCCCCEEECCHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEECCCCCEEECCCCCHHH
MIKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEILRRIGRRIHRDIVVRGDYWI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEE
RVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFSIEDLDAVIVTH
EEEEECCHHHHCCCEEEEECCCCEEEEECCCCEEECCCCCCCCCCCCCCHHHCCEEEEEE
AHLDHCGFIPGLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDIKTCV
HHHHHCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KHTIPIDYGVTTDISPTIKLTLHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKFETSRLLE
HHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEEECCCCEEEEEECCEEECHHHCCC
PAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVSETTDRGGKVLIPVFGVGRAQ
HHHHCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
ELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDNPFLSEVF
HHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
KRVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGYQAEGTLG
HHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCHH
RKVQSGWKEIPIITRNGKTKSIPINLQVYTIEGFSGHSDRKQLIKYIRRLKPSPEKIIMV
HHHHCCHHHCCEEEECCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEE
HGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEC
>Mature Secondary Structure 
SAEEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTNEIIKSLAKDLRKRI
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
SIRPDPSVLVEPEIAKQKILEIVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLE
CCCCCCCEEECCHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEECCCCCEEECCCCCHHH
MIKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEILRRIGRRIHRDIVVRGDYWI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEE
RVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFSIEDLDAVIVTH
EEEEECCHHHHCCCEEEEECCCCEEEEECCCCEEECCCCCCCCCCCCCCHHHCCEEEEEE
AHLDHCGFIPGLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDIKTCV
HHHHHCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KHTIPIDYGVTTDISPTIKLTLHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKFETSRLLE
HHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEEECCCCEEEEEECCEEECHHHCCC
PAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVSETTDRGGKVLIPVFGVGRAQ
HHHHCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
ELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDNPFLSEVF
HHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
KRVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGYQAEGTLG
HHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCHH
RKVQSGWKEIPIITRNGKTKSIPINLQVYTIEGFSGHSDRKQLIKYIRRLKPSPEKIIMV
HHHHCCHHHCCEEEECCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEE
HGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087