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The map label for this gene is ycdQ [C]

Identifier: 15669407

GI number: 15669407

Start: 1164978

End: 1165709

Strand: Reverse

Name: ycdQ [C]

Synonym: MJ1222

Alternate gene names: 15669407

Gene position: 1165709-1164978 (Counterclockwise)

Preceding gene: 15669408

Following gene: 15669405

Centisome position: 70.01

GC content: 31.83

Gene sequence:

>732_bases
GTGGAGATAATGAAAAAGCAAAACAGCCAAATTAATGAGATTAATAAAGATGAGATATTTGTAGTCGTTCCTGCATTCAA
TGAAGAAAAGATGATTGGAGAAACTTTAAAGAATTTAAAAAAAGAGGGCTATAAAAATATAGTAGTTGTTGATGATGGTT
CAATGGATAAAACTTCAGAGATAGCTAAAAAAGAGGGAGTTATAGTCTGTAGGCATATATTGAATAGAGGGTTAGGGGGA
GCTTTAGGGACTGGGATTAAATGTGCTCTGCTATATAAACCAAAAATCATCATTACCTTTGATGCAGATGGGCAACATCA
TCCAAAAGACGTTGAGAAGGTTGTTAAGCCAGTATTATTTGAAGGCTATGATATGGCTATTGGTAGTAGGATGATGGATA
AGAATGAGTTAAAGAATATGCCATTAGTTAAAAGGATTGGGAATTTTGGCTTAAATTTTATAACTTATTTGATGGGAGGG
TATTTTGTTACAGACAGCCAAAGTGGATTGAGAGCTTTCTCTTATGAAGCGGCTAAGAAAATAATAGGGGATTTAAAGAG
TGATAGGTATGAAGTTTCCTCTGAATTTATAATTTTAGCTAAAAAACATGGATTAAAGCTTAAAGAAGTGCCAATAAAAA
CTATATATACTGAATATTCGATGAGTAGAGGAACTAATGTAATAACTGGGTTTAAAATTTTATTTAAGTTGATTATGCAG
AAGATTTTTTAA

Upstream 100 bases:

>100_bases
GTTATCTCCCAAAAATACAACCTTGCATTTGCCGATACTATAGCCTTAGCCATCTTTATATGTGGGGTTGTTGGGGCATT
TGCCTTCTGTAAGGTTATAG

Downstream 100 bases:

>100_bases
AATGGAAAAATAAGAGTTTTTAATATTTTATTTTTTGATTTATCTTTCCAACTTTGTATTTTAAGCCAATGTAGCCACCA
ACATCTAATAACACTATGTT

Product: dolichol-P-glucose synthetase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MEIMKKQNSQINEINKDEIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSEIAKKEGVIVCRHILNRGLGG
ALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMDKNELKNMPLVKRIGNFGLNFITYLMGG
YFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEVSSEFIILAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIMQ
KIF

Sequences:

>Translated_243_residues
MEIMKKQNSQINEINKDEIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSEIAKKEGVIVCRHILNRGLGG
ALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMDKNELKNMPLVKRIGNFGLNFITYLMGG
YFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEVSSEFIILAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIMQ
KIF
>Mature_243_residues
MEIMKKQNSQINEINKDEIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSEIAKKEGVIVCRHILNRGLGG
ALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMDKNELKNMPLVKRIGNFGLNFITYLMGG
YFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEVSSEFIILAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIMQ
KIF

Specific function: Unknown

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7019323, Length=240, Percent_Identity=27.9166666666667, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI4503363, Length=235, Percent_Identity=26.8085106382979, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25146207, Length=246, Percent_Identity=27.2357723577236, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71999402, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325029, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582769, Length=245, Percent_Identity=30.6122448979592, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24585265, Length=237, Percent_Identity=28.2700421940928, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1222_METJA (Q58619)

Other databases:

- EMBL:   L77117
- PIR:   E64452
- RefSeq:   NP_248217.1
- ProteinModelPortal:   Q58619
- GeneID:   1452118
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1222
- NMPDR:   fig|243232.1.peg.1254
- TIGR:   MJ1222
- HOGENOM:   HBG752660
- OMA:   KTIYTEY
- ProtClustDB:   CLSK876495
- BioCyc:   MJAN243232:MJ_1222-MONOMER
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: 2.4.1.83

Molecular weight: Translated: 27429; Mature: 27429

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMKKQNSQINEINKDEIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSE
CCCHHHCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IAKKEGVIVCRHILNRGLGGALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLF
HHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHH
EGYDMAIGSRMMDKNELKNMPLVKRIGNFGLNFITYLMGGYFVTDSQSGLRAFSYEAAKK
CCCCHHHHHHHCCHHHHCCCHHHHHHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHH
IIGDLKSDRYEVSSEFIILAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIMQ
HHHHHCCCCEECCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KIF
HHC
>Mature Secondary Structure
MEIMKKQNSQINEINKDEIFVVVPAFNEEKMIGETLKNLKKEGYKNIVVVDDGSMDKTSE
CCCHHHCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IAKKEGVIVCRHILNRGLGGALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLF
HHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHH
EGYDMAIGSRMMDKNELKNMPLVKRIGNFGLNFITYLMGGYFVTDSQSGLRAFSYEAAKK
CCCCHHHHHHHCCHHHHCCCHHHHHHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHH
IIGDLKSDRYEVSSEFIILAKKHGLKLKEVPIKTIYTEYSMSRGTNVITGFKILFKLIMQ
HHHHHCCCCEECCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KIF
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087