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The map label for this gene is mat

Identifier: 15669394

GI number: 15669394

Start: 1151375

End: 1152595

Strand: Direct

Name: mat

Synonym: MJ1208

Alternate gene names: 15669394

Gene position: 1151375-1152595 (Clockwise)

Preceding gene: 15669393

Following gene: 15669406

Centisome position: 69.15

GC content: 34.64

Gene sequence:

>1221_bases
ATGAGAAACATAATTGTAAAAAAATTAGATGTTGAACCAATTGAAGAAAGACCAACTGAAATTGTTGAGAGGAAGGGATT
GGGGCATCCAGATTCAATTTGTGATGGTATTGCTGAGAGTGTTAGTAGGGCTTTATGTAAGATGTACATGGAGAAGTTTG
GAACTATTTTGCACCACAATACAGACCAAGTTGAGCTTGTAGGGGGACATGCATATCCTAAGTTTGGAGGAGGAGTAATG
GTAAGCCCTATTTATATTTTATTATCTGGAAGAGCAACAATGGAAATCTTAGATAAGGAGAAAAATGAAGTTATAAAGCT
CCCAGTAGGAACAACTGCTGTTAAAGCTGCTAAAGAATATTTAAAGAAGGTTTTAAGAAATGTTGATGTTGATAAAGATG
TTATTATTGACTGCAGAATTGGGCAGGGAAGTATGGATTTAGTTGATGTCTTTGAGAGACAAAAGAATGAAGTTCCTTTA
GCTAATGATACATCATTTGGAGTAGGTTATGCTCCATTATCAACAACAGAGAGGTTAGTTTTAGAAACAGAGAGATTTTT
AAATAGTGATGAGTTAAAGAATGAGATTCCAGCTGTAGGAGAGGACATAAAGGTTATGGGATTAAGAGAGGGTAAGAAGA
TAACTTTAACCATTGCTATGGCTGTTGTTGATAGGTATGTTAAAAATATTGAGGAATATAAGGAAGTTATTGAAAAGGTT
AGAAAGAAGGTTGAAGATTTAGCTAAGAAGATAGCTGATGGATATGAGGTTGAAATTCATATAAATACAGCAGATGATTA
TGAGAGGGAGAGTGTCTATCTAACAGTTACTGGAACATCAGCAGAGATGGGGGATGATGGTTCAGTTGGGAGAGGAAATA
GAGTTAATGGATTGATAACTCCATTCAGACCTATGAGTATGGAGGCAGCAAGTGGTAAAAACCCAGTAAATCACGTTGGT
AAAATCTACAATATCTTAGCAAACTTAATAGCAAACGATATTGCCAAATTGGAAGGAGTTAAAGAGTGCTATGTTAGAAT
ATTAAGCCAAATTGGTAAGCCAATCAATGAGCCAAAGGCTTTAGATATAGAAATTATAACTGAAGATAGCTATGATATAA
AGGATATTGAACCAAAAGCAAAAGAGATAGCCAATAAATGGTTAGATAACATCATGGAAGTTCAAAAGATGATTGTTGAA
GGAAAAGTAACTACATTCTAA

Upstream 100 bases:

>100_bases
AGGGAGTTTTTAGCTTTCTATTTTATAAGAGGATTAACTTTAAATATAAAAAATTTATTTTATCATTTTACTTATTGATA
ATTAGGACATGGTGATATAG

Downstream 100 bases:

>100_bases
ATCTAAATAAATTATAATTTCTTAGAAATTTCTATAATGTCTTCAACAATTTTTCCAAAATGTTTTGCTTTTTCTGTTTC
TTCAAAGTCCTCTTTTAGGA

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHNTDQVELVGGHAYPKFGGGVM
VSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEYLKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPL
ANDTSFGVGYAPLSTTERLVLETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKV
RKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLITPFRPMSMEAASGKNPVNHVG
KIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKALDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVE
GKVTTF

Sequences:

>Translated_406_residues
MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHNTDQVELVGGHAYPKFGGGVM
VSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEYLKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPL
ANDTSFGVGYAPLSTTERLVLETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKV
RKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLITPFRPMSMEAASGKNPVNHVG
KIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKALDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVE
GKVTTF
>Mature_406_residues
MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHNTDQVELVGGHAYPKFGGGVM
VSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEYLKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPL
ANDTSFGVGYAPLSTTERLVLETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKV
RKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLITPFRPMSMEAASGKNPVNHVG
KIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKALDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVE
GKVTTF

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METK_METJA (Q58605)

Other databases:

- EMBL:   L77117
- PIR:   G64450
- RefSeq:   NP_248203.1
- ProteinModelPortal:   Q58605
- GeneID:   1452105
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1208
- NMPDR:   fig|243232.1.peg.1240
- TIGR:   MJ1208
- HOGENOM:   HBG297280
- OMA:   RPMSMEA
- ProtClustDB:   PRK04439
- BioCyc:   MJAN243232:MJ_1208-MONOMER
- BRENDA:   2.5.1.6
- HAMAP:   MF_00136
- InterPro:   IPR002795
- ProDom:   PD011777

Pfam domain/function: PF01941 AdoMet_Synthase

EC number: =2.5.1.6

Molecular weight: Translated: 45253; Mature: 45253

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHN
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDQVELVGGHAYPKFGGGVMVSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEY
CCCEEEEECCCCCCCCCCEECCEEEHEECCCHHHHHHHCCCCCEEEECCCHHHHHHHHHH
LKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPLANDTSFGVGYAPLSTTERLV
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKV
HHHHHHCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLIT
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEC
PFRPMSMEAASGKNPVNHVGKIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVEGKVTTF
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHN
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDQVELVGGHAYPKFGGGVMVSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEY
CCCEEEEECCCCCCCCCCEECCEEEHEECCCHHHHHHHCCCCCEEEECCCHHHHHHHHHH
LKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPLANDTSFGVGYAPLSTTERLV
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKV
HHHHHHCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLIT
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEC
PFRPMSMEAASGKNPVNHVGKIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVEGKVTTF
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 10660563