Click here to switch to the map view.

The map label for this gene is fwdC

Identifier: 15669360

GI number: 15669360

Start: 1110567

End: 1111388

Strand: Direct

Name: fwdC

Synonym: MJ1171

Alternate gene names: 15669360

Gene position: 1110567-1111388 (Clockwise)

Preceding gene: 15669359

Following gene: 15669361

Centisome position: 66.7

GC content: 35.28

Gene sequence:

>822_bases
ATGAAGGAGTTAATTCTAACATTACAAAAGGAAATTATTGTTCCAGTAGAGATGGATAAAGTATTGCCAGAAGTTATTGA
GAACATGAGCTTAGAGGAAATAAAAAACATTGAGTTAGTCCAAGGAAGAAAAAGAATTAAAGTTGCTGACATCTTTGATG
TTGAATTAAATGATATTGAAGGAGAACCAAGAATTGTAATTAAAAACTCAAGTCCAAAATTAAAATACATTGGTTCAAAG
ATGACAAAGGGAGAGATTGTTGTTGAAGGAGATGCTGGAATGTATGTTGGGGCAGAGATGAAGGGAGGAAAGATAGTTGT
TAATGGAAATGCTGAGAGCTGGGCTGGACAGAATATGAAAGGAGGAGAGCTTTTAATCAAAGGAAATGCAGGAGATTACG
TTGGTTCTGCGTATAGGGGAGACTGGAGAGGTATGAGTGGAGGAACAATTATTGTTGAAGGAAACGCTGGAAATGAGATT
GGAGAGTTTATGAGTAAAGGTCTCATACATATAAAAGGAAATGTTGGAATAATGGCTGGAATTCATCAAAATGGAGGAAT
AATTATTATTGATGGAGATGTTGATGTGAGAGTTGGAGGAGAGATGAAGGCAGGAGCTATAGTTGTCTATGGAAAGGTTG
AAGAGATTTTACCTTCATTCAAGTTTGAGGGTATTGTGGAGAATCCAGTTATAAAATTAAGTAAAAAAGACGCTGGAACA
CCAATAGCAGGAACCTTCTATAAGTTTAGTGGAGATTATGTCTATAATAAACCAAAAGGGCAGTTATATATTTCAGTTGA
TAGCAATCCAGATTTAATTTAA

Upstream 100 bases:

>100_bases
GATGAAAACTATGCAGTTCCAGAATTAACCTACTATGCATATGGAACGGCTGTTATAGTTGAGAAAATTGACTGATAAAA
AATAATAAGCCGGTGATGGT

Downstream 100 bases:

>100_bases
TTTTGAAAAACATATTTCTTATTTTTCTACAAAGTTTCATAAAATCTCAATAGAAATTCTTTTTTATTATCGAAGCATAA
AACTATTTATACAAATATTT

Product: formylmethanofuran dehydrogenase subunit FwdC

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit C

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIEGEPRIVIKNSSPKLKYIGSK
MTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMKGGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEI
GEFMSKGLIHIKGNVGIMAGIHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGT
PIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI

Sequences:

>Translated_273_residues
MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIEGEPRIVIKNSSPKLKYIGSK
MTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMKGGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEI
GEFMSKGLIHIKGNVGIMAGIHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGT
PIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI
>Mature_273_residues
MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIEGEPRIVIKNSSPKLKYIGSK
MTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMKGGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEI
GEFMSKGLIHIKGNVGIMAGIHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGT
PIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile

COG id: COG2218

COG function: function code C; Formylmethanofuran dehydrogenase subunit C

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdC/fmdC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDC_METJA (Q58571)

Other databases:

- EMBL:   L77117
- PIR:   B64446
- RefSeq:   NP_248165.1
- ProteinModelPortal:   Q58571
- SMR:   Q58571
- GeneID:   1452069
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1171
- NMPDR:   fig|243232.1.peg.1202
- TIGR:   MJ1171
- HOGENOM:   HBG541237
- OMA:   YVGSAYR
- ProtClustDB:   CLSK876482
- BioCyc:   MJAN243232:MJ_1171-MONOMER
- BRENDA:   1.2.99.5
- GO:   GO:0015948
- InterPro:   IPR017550
- InterPro:   IPR002489
- Gene3D:   G3DSA:2.160.20.60
- TIGRFAMs:   TIGR03122

Pfam domain/function: PF01493 GXGXG; SSF69336 Glu_synthase_C

EC number: =1.2.99.5

Molecular weight: Translated: 29462; Mature: 29462

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIE
CCHHHEEEHHHEEEEECHHHHHHHHHHCCCHHHHCCEEEECCCCEEEEEEEEEEEEECCC
GEPRIVIKNSSPKLKYIGSKMTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMK
CCCEEEEECCCCCEEEECCCCCCCEEEEECCCCEEEEEEECCCEEEECCCCCCCCCCCCC
GGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEIGEFMSKGLIHIKGNVGIMAG
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCEEEEECCEEEEEE
IHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGT
EECCCCEEEEECCEEEEECCCCCCCEEEEEECHHHHCCCCCCCCEECCCEEEEECCCCCC
PIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI
CEEEEEEEEECCEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIE
CCHHHEEEHHHEEEEECHHHHHHHHHHCCCHHHHCCEEEECCCCEEEEEEEEEEEEECCC
GEPRIVIKNSSPKLKYIGSKMTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMK
CCCEEEEECCCCCEEEECCCCCCCEEEEECCCCEEEEEEECCCEEEECCCCCCCCCCCCC
GGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEIGEFMSKGLIHIKGNVGIMAG
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCEEEEECCEEEEEE
IHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGT
EECCCCEEEEECCEEEEECCCCCCCEEEEEECHHHHCCCCCCCCEECCCEEEEECCCCCC
PIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI
CEEEEEEEEECCEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087