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The map label for this gene is fwdD

Identifier: 15669357

GI number: 15669357

Start: 1108108

End: 1108509

Strand: Direct

Name: fwdD

Synonym: MJ1168

Alternate gene names: 15669357

Gene position: 1108108-1108509 (Clockwise)

Preceding gene: 15669356

Following gene: 15669358

Centisome position: 66.55

GC content: 36.07

Gene sequence:

>402_bases
ATGAAGTTTTTCTTAAACACAGGCAGAACTATTTGGCAAGGGGAGGCAATGGAGGCTGGAAAAAACCTTGATTTGTATGT
TAAAGCTGCTGGAGTAGTTTATATCAACGAAGAAGATATGGAGAAATTAGGAGTTAAAGAAGGAGATAAAGTTAAAGTTA
AGTCAGAATATGGAGAAGTTGTAGTTTATGTAAAAAAAGCAACTGAAAGAATGCCAGAAGGAATGATTTACATCCCAATG
GGACCTTGGGCAAACTGTGTTGTTAAACCAGACACACACAGCACTGGAATGCCGACATTTAAAGGATATCCTGGCTTTTA
CGTTGAAGTTGAGAAGACAGACGAAGAATTTTTAGATATGAGGTCTTTAATGAGAAAAAAATACATTGAAGCTGTTGAAT
AA

Upstream 100 bases:

>100_bases
ATCAAGATTTATGTGGTGGATGTGGAGCTTGCATAGAAGCATGCCCAGTTAATGCTATAGAGTTAGTTTTTAAAAGAAAA
TAAGCTAAATTGGTGAGATA

Downstream 100 bases:

>100_bases
ACCAAATATTAATAAATGGTGATAAGATGGAATATATCATAAAAAATGGAATTGTTTATGACCCATTAAATGGGATTAAT
GGAGAAAAAATGGATATATG

Product: formylmethanofuran dehydrogenase subunit FwdD

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MKFFLNTGRTIWQGEAMEAGKNLDLYVKAAGVVYINEEDMEKLGVKEGDKVKVKSEYGEVVVYVKKATERMPEGMIYIPM
GPWANCVVKPDTHSTGMPTFKGYPGFYVEVEKTDEEFLDMRSLMRKKYIEAVE

Sequences:

>Translated_133_residues
MKFFLNTGRTIWQGEAMEAGKNLDLYVKAAGVVYINEEDMEKLGVKEGDKVKVKSEYGEVVVYVKKATERMPEGMIYIPM
GPWANCVVKPDTHSTGMPTFKGYPGFYVEVEKTDEEFLDMRSLMRKKYIEAVE
>Mature_133_residues
MKFFLNTGRTIWQGEAMEAGKNLDLYVKAAGVVYINEEDMEKLGVKEGDKVKVKSEYGEVVVYVKKATERMPEGMIYIPM
GPWANCVVKPDTHSTGMPTFKGYPGFYVEVEKTDEEFLDMRSLMRKKYIEAVE

Specific function: Unknown

COG id: COG1153

COG function: function code C; Formylmethanofuran dehydrogenase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDD_METJA (Q58568)

Other databases:

- EMBL:   L77117
- PIR:   G64445
- RefSeq:   NP_248162.1
- ProteinModelPortal:   Q58568
- SMR:   Q58568
- GeneID:   1452066
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1168
- NMPDR:   fig|243232.1.peg.1199
- TIGR:   MJ1168
- HOGENOM:   HBG541497
- OMA:   GRTIWQG
- ProtClustDB:   CLSK876481
- BioCyc:   MJAN243232:MJ_1168-MONOMER
- InterPro:   IPR009010
- InterPro:   IPR012040
- InterPro:   IPR006657
- Gene3D:   G3DSA:2.40.40.20
- PIRSF:   PIRSF015873

Pfam domain/function: PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: 1.2.99.5

Molecular weight: Translated: 15207; Mature: 15207

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFLNTGRTIWQGEAMEAGKNLDLYVKAAGVVYINEEDMEKLGVKEGDKVKVKSEYGEV
CEEEECCCCEEEECCHHHCCCCCEEEEEEEEEEEECCHHHHHCCCCCCCEEEEECCCCEE
VVYVKKATERMPEGMIYIPMGPWANCVVKPDTHSTGMPTFKGYPGFYVEVEKTDEEFLDM
EEEEEHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
RSLMRKKYIEAVE
HHHHHHHHHHHCC
>Mature Secondary Structure
MKFFLNTGRTIWQGEAMEAGKNLDLYVKAAGVVYINEEDMEKLGVKEGDKVKVKSEYGEV
CEEEECCCCEEEECCHHHCCCCCEEEEEEEEEEEECCHHHHHCCCCCCCEEEEECCCCEE
VVYVKKATERMPEGMIYIPMGPWANCVVKPDTHSTGMPTFKGYPGFYVEVEKTDEEFLDM
EEEEEHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
RSLMRKKYIEAVE
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087