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The map label for this gene is 15669329

Identifier: 15669329

GI number: 15669329

Start: 1081427

End: 1082476

Strand: Direct

Name: 15669329

Synonym: MJ1142

Alternate gene names: NA

Gene position: 1081427-1082476 (Clockwise)

Preceding gene: 15669328

Following gene: 15669330

Centisome position: 64.95

GC content: 36.95

Gene sequence:

>1050_bases
ATGTTATCAAAAATTAAAGATTCAATAAACTCATTGAGAGGAATTACAGAGAAAAAATTGGAAAAGAAGGATGGAACTAA
ATACATCATGTTCGGAGGTAAAGGAGGAGTTGGAAAAACAACAATGAGTGCTGCAACAGGAGTTTATTTGGCTGAAAAAG
GACTGAAAGTTGTTATCGTCTCAACAGACCCAGCTCACTCTTTGAGAGATATCTTTGAGCAAGAGTTTGGACATGAGCCA
ACAAAGGTTAAGGGCTATGACAACCTATATGTTGTAGAGATAGACCCACAGAAGGCTATGGAAGAGTATAAAGAAAAATT
AAAAGCTCAAATTGAAGAAAACCCATTCTTAGGAGAGATGTTAGAAGACCAATTAGAGATGGCCGCTCTCTCCCCAGGAA
CTGATGAAAGTGCTGCATTTGATGTTTTCCTCAAATATATGGATAGCAATGAGTTTGATGTAGTTATATTTGACACCGCT
CCAACTGGACACACTTTAAGGTTTTTAGGAATGCCAGAGGTTATGGACAAGTATATGACAAAGCTTATAAAGTTGAGGAA
GCAGATGAGCGGATTTATGAAGATGATGAAAAAGCTTTTACCATTTGGAGGTAAAGATGAAGATATCGATTACGATAAGA
TGTTGGAAGAATTAGAGAAGATGAAGGAGAGAATAGTTAGAGCAAGAAACATCTTATCAGACCCAGAGAGAACTGCATTT
AGATTAGTGGTTATTCCAGAGGAGATGAGTATCTTAGAGAGTGAGAGGGCAATGAAAGCTCTTCAAAAGTATGGTATTCC
AATCGATGCAGTTATTGTAAATCAACTCATTCCAGAGGATGTTCAGTGTGATTTCTGTAGAGCAAGAAGAGAGTTGCAGT
TGAAGAGATTAGAGATGATTAAAGAGAAATTTGGAGACAAGGTTATTGCCTATGTCCCTCTCTTAAGAACTGAGGCAAAG
GGTATTGAAACATTAAAACAGATAGCAAAAATATTGTATGGTGAAGAGGAGAAAGAAGAACAAAAAATAGAGCAAAAGGT
TGGCCAATAA

Upstream 100 bases:

>100_bases
GACAACCTTTATTAAGGGATGGTTGTATAAATACTTTGGTCGATGTTGATGAACTAATTACAAGATTAAAATCATTATAA
TAATAAGAGGGTGAAAATAA

Downstream 100 bases:

>100_bases
ATTATTTTTAATTTTTAATTTTTCTTTTTAACTGAGGGTATAATGACAATAACTCAAATGATAAGTGAGATTTTAATGCA
CAATACTGTATATAATTATA

Product: arsenical pump-driving ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLSKIKDSINSLRGITEKKLEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHEP
TKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEMLEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTA
PTGHTLRFLGMPEVMDKYMTKLIKLRKQMSGFMKMMKKLLPFGGKDEDIDYDKMLEELEKMKERIVRARNILSDPERTAF
RLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMIKEKFGDKVIAYVPLLRTEAK
GIETLKQIAKILYGEEEKEEQKIEQKVGQ

Sequences:

>Translated_349_residues
MLSKIKDSINSLRGITEKKLEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHEP
TKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEMLEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTA
PTGHTLRFLGMPEVMDKYMTKLIKLRKQMSGFMKMMKKLLPFGGKDEDIDYDKMLEELEKMKERIVRARNILSDPERTAF
RLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMIKEKFGDKVIAYVPLLRTEAK
GIETLKQIAKILYGEEEKEEQKIEQKVGQ
>Mature_349_residues
MLSKIKDSINSLRGITEKKLEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHEP
TKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEMLEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTA
PTGHTLRFLGMPEVMDKYMTKLIKLRKQMSGFMKMMKKLLPFGGKDEDIDYDKMLEELEKMKERIVRARNILSDPERTAF
RLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMIKEKFGDKVIAYVPLLRTEAK
GIETLKQIAKILYGEEEKEEQKIEQKVGQ

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family

Homologues:

Organism=Homo sapiens, GI50428938, Length=324, Percent_Identity=36.1111111111111, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17557003, Length=334, Percent_Identity=35.6287425149701, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71990781, Length=155, Percent_Identity=30.9677419354839, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320103, Length=314, Percent_Identity=32.1656050955414, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586297, Length=318, Percent_Identity=35.5345911949685, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARSA_METJA (Q58542)

Other databases:

- EMBL:   L77117
- PIR:   E64442
- RefSeq:   NP_248134.1
- ProteinModelPortal:   Q58542
- SMR:   Q58542
- GeneID:   1452038
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1142
- NMPDR:   fig|243232.1.peg.1171
- TIGR:   MJ1142
- HOGENOM:   HBG646947
- OMA:   IPEEMSI
- ProtClustDB:   CLSK876470
- BioCyc:   MJAN243232:MJ_1142-MONOMER
- BRENDA:   3.6.3.16
- InterPro:   IPR003348
- TIGRFAMs:   TIGR00345

Pfam domain/function: NA

EC number: =3.6.3.16

Molecular weight: Translated: 39919; Mature: 39919

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKIKDSINSLRGITEKKLEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIV
CCHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEEE
STDPAHSLRDIFEQEFGHEPTKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEM
ECCCCHHHHHHHHHHHCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHH
LEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTAPTGHTLRFLGMPEVMDKYMT
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHH
KLIKLRKQMSGFMKMMKKLLPFGGKDEDIDYDKMLEELEKMKERIVRARNILSDPERTAF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
RLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMI
EEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KEKFGDKVIAYVPLLRTEAKGIETLKQIAKILYGEEEKEEQKIEQKVGQ
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLSKIKDSINSLRGITEKKLEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIV
CCHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEEE
STDPAHSLRDIFEQEFGHEPTKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEM
ECCCCHHHHHHHHHHHCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHH
LEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTAPTGHTLRFLGMPEVMDKYMT
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHH
KLIKLRKQMSGFMKMMKKLLPFGGKDEDIDYDKMLEELEKMKERIVRARNILSDPERTAF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
RLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMI
EEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KEKFGDKVIAYVPLLRTEAKGIETLKQIAKILYGEEEKEEQKIEQKVGQ
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087