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The map label for this gene is rpoA1

Identifier: 15669231

GI number: 15669231

Start: 974606

End: 978631

Strand: Direct

Name: rpoA1

Synonym: MJ1042

Alternate gene names: 15669231

Gene position: 974606-978631 (Clockwise)

Preceding gene: 15669230

Following gene: 15669232

Centisome position: 58.54

GC content: 35.54

Gene sequence:

>4026_bases
ATGGAGAGGTATGAAATCCCTAAAGAGATTGGAGAAATAATGTTTGGCTTGTTGTCTCCAGATTACATAAGACAGATGTC
AGTTGCTAAGATAGTTACACCAGACACTTATGATGAAGATGGTTATCCAATAGATGGAGGTTTAATGGACACAAGATTGG
GAGTTATAGACCCAGGTTTAGTTTGCAAAACATGTGGAGGAAGGATTGGAGAGTGTCCAGGGCATTTTGGGCATATAGAG
TTGGCTAAACCAGTAATTCATATAGGATTTGCCAAAACAATATACAAGATATTGAAGGCAGTTTGCCCACACTGTGGAAG
AGTAGCAATAAGTGAAACTAAGAGGAAAGAAATTTTGGAAAAGATGGAAAAATTAGAGAGAGATGGAGGAAACAAGTGGG
AGGTTTGTGAAGAGGTTTATAAAGAAGCTTCAAAAGTTACAATCTGCCCACACTGTGGAGAGATAAAGTATGATATAAAG
TTTGAGAAACCAACAACCTACTACAGAATTGATGGAAATGAGGAAAAAACATTAACTCCATCAGATGTTAGAGAGATTTT
AGAGAAGATTCCAGATGAAGATTGTATCTTACTCGGCTTAAACCCAGAGGTTGCAAGGCCAGAGTGGATGGTTCTCACCG
TTTTGCCAGTTCCACCAGTAACTGTAAGGCCATCAATTACCTTGGAAACTGGAGAGAGAAGTGAAGACGATTTAACTCAC
AAGTTAGTTGATATCATCAGAATCAACAATAGATTAGAGGAGAATATAGAAGGAGGAGCACCAAACTTAATTATTGAGGA
TTTATGGAATCTGTTGCAGTATCACGTAAATACCTACTTCGATAACGAAGCTCCAGGTATTCCACCAGCTAAGCACAGAA
GTGGAAGACCATTAAAAACCTTAGCTCAGAGATTAAAAGGTAAAGAAGGAAGGTTCAGATACAACTTAGCTGGTAAGAGG
GTTAATTTCTCATCAAGAACAGTTATCTCTCCAGACCCATGTTTAAGTATTAATGAAGTTGGAGTTCCAGAGGTTGTGGC
TAAAGAGCTAACCGTCCCAGAGAAGGTAACGAAATACAACATTGAGAGAATTAGGCAGTTATTAAGAAATGGTTCAGAGA
AACACCCAGGAGTTAATTATGTTATAAGAAAGATGATTGGTAGAGATGGAACAGAGCAGGAATATAAGGTTAAGATAACT
GAAAGCAATAAAGACTTCTGGGCAGAGAATATAAGAGAAGGAGATATTGTTGAAAGGCACTTAATGGATGGAGATATTGT
CTTATACAACAGACAGCCATCACTGCATAGAATGTCTATTATGGCACATAGAGTTAGAGTTCTCCCATACAGAACATTTA
GACACAATTTATGCGTATGTGTAGATGGAGACACCACAGTGTTGTTAGATGGGAAATTAATTAAAATTAAGGACTTAGAA
GATAAATGGAAAGATGTCAAAGTTTTAACTTCAGATGATTTAAATCCAAAACTAACTTCATTAAGCAAGTATTGGAAATT
AAACGCAGATGAGTATGGAAAGAAGATTTATAAAATAAAAACAGAGCTTGGAAGAGAAATTATAGCAACAGAAGACCATC
CATTCTATACAACAAATGGTAGAAAGAGATGCGGTGAGTTGAAAGTTGGAGATGAAGTTATAATATATCCAAACGACTTC
CCAATGTTTGAAGATGACAATAGAGTAATAGTTGATGAAGAAAAAATCAAGAAGGTAATTAATAACATTGGAGGAACTTA
CAAAAATAAAATTATTAATGAGCTAAAAGATAGGAAGTTAATTCCTTTGACATACAATGACCAAAAGGCATCAATATTGG
CAAGGATTGTTGGACATGTAATGGGAGATGGTTCTTTAATAATAAACAATAAAAATTCAAGAGTTGTATTTAGAGGAGAT
ATTGAGGATTTAAAAACAATAAAAGAGGACTTAAAAGAATTAGGTTATGATGGGGAGGAAATAAAACTACATGAAGGAGA
AACTGAAATAACAGATTACAACGGCAAGAAAAGAATAATTAAAGGCAAAGGTTATAGCTTTGAAGTTAGGAAAAAATCGT
TATGCATACTATTAAAAGCCCTTGGTTGTGTAGGTGGAGATAAAACTAAAAAGATGTATGGCATTCCAAATTGGATTAAA
ACTGCTCCAAAGTATATAAAGAAAGAGTTTTTATCAGCCTACTTCGGTTCGGAATTAACAACTCCAAAAATTAGAAATCA
TGGGACTTCATTTAAAGAGTTATCATTCAAAATAGCTAAGATTGAGGAGATATTTGACGAAGATAGATTCATTAAAGACA
TTAAAGAGATGCTAAAAGAATTTGGTATTGAATTAAAGGTTAGGGTTGAAGAAGGCAATCTAAGAAAAGATGGTTATAAA
ACAAAAGTTTATGTTGCGTCAATATACAACCATAAAGAATTCTTTGGAAGAATTGGATATACCTATGCTAACAAAAAAGA
AACATTAGCAAGATATGCTTATGAATACCTCCTTACAAAAGAGAAATATCTAAAAGACAGAAACATTAAAAAATTAGAAA
ATAACACCAAATTTATTACATTTGATAAGTTTATAAAAGAGAAATGCCTTAAGAATGGATTTGTAAAAGAAAAAATTGTA
AGTATTGAAGAAACAAAAGTAGATTATGTCTATGATATAACTACAATCTCAGAAACTCACAATTTCATTGCAAACGGCTT
TTTAACAGGAAATTGCCCGCCCTACAACGCTGACTTTGATGGAGATGAGATGAACTTACACGTTCCACAATCAGAGGAGG
CAAGAGCAGAGGCAGAAGCTTTAATGCTTGTAGAAAAACACATCCTTTCACCAAGATTTGGAGGGCCTATAATTGGAGCT
ATACACGACTTTATTTCAGGAGCTTATCTCTTAACCTCAAACTACTTCACAAAAGATGAAGCTACTTTAATCTTAAGAAG
TGGGGGAATAAAGGATGAGTTATGGGAGCCAGATAAGGTAGAGAATGGAGTTCCATTATACTCCGGTAAGAAGATATTCA
GTAAAGCATTACCAAAAGGATTGAATTTGAGATATAAAGCAAAGATTTGTAGAAAGTGTGATGTGTGCAAAAAAGAGGAA
TGTGAATACGATGCCTATGTTGTAATAAAAGATGGGGAGTTAATTAAAGGAGTTATTGATAAAAACGGTTACGGGGCAGA
GGCAGGTTTAATCTTACACACAATAGTTAAAGAGTTTGGTCCAGAAGCTGGAAGAAAATTCCTTGACTCAGCTACTAAGA
TGGCAATAAGGGCAGTGATGTTAAGAGGATTTACTACAGGAATTGATGATGAAGATTTACCAGAAGAAGCATTAAAAGAG
ATTGAAAAAGTCTTAGATGAGGCAGAAGAGAAAGTTAAAGAAATCATCGAGAAATATGAAAGAGGAGAACTTGAATTGCT
TCCAGGTTTGAACTTGGAGGAGTCAAGGGAGGCATATATAAGCAATGTTTTAAGAGAGGCAAGAGACAAAGCTGGAGCTA
TTGCTGAGAGATACTTAGGTTTGGATAACCATGCGGTTATCATGGCAGTTACTGGGGCGAGAGGGAACATCTTAAACTTA
ACACAGATGGCGGCATGTTTAGGGCAGCAGTCAGTTAGAGGTAAGAGAATCTTTAGAGGTTACAGGGGTAGAGTATTGCC
TCATTTCGAAAAAGGAGATTTAGGAGCAAGGTCTCACGGGTTTGTTAGAAGTAGTTATAAGAAGGGGTTAAGTCCAACAG
AGTTCTTCTTCCACGCTATGGGAGGTAGAGAAGGATTGGTTGACCAGGCAGTTAGAACTGCTCAGTCTGGTTACATGCAG
AGAAGATTAATTAACGCTCTACAAGACTTAAAGACAGAGTTCGATGGAACCGTTAGAGATTCAAGAGGAATTATGATTCA
ATTTAAGTATGGAGAGGATGGAATTGACCCAATGCTTGCTGATAGAGGTAAGGCAGTAAATATTGACAGAATAATTGATA
AGGTTAAGATGAAGTATAACCAATAA

Upstream 100 bases:

>100_bases
ATTAAAAGACCTTGCTTAACCTTAATCTTGCCTTATTACAATATTTTTAGAAAAATAAAAAGTAAAAATAAAAGCAAATC
CTTAATCTTTGGTGATATTG

Downstream 100 bases:

>100_bases
ATCTCTAAATTCAAAAATTTCAAAACTTTTTCAAAACAATTTTTACATCTTTTAATTTTTTAAGGTGAGAATACATGGAC
ATGGAAGCATTAAAACAAAA

Product: DNA-directed RNA polymerase subunit alpha

Products: NA

Alternate protein names: Mja rpol A' intein

Number of amino acids: Translated: 1341; Mature: 1341

Protein sequence:

>1341_residues
MERYEIPKEIGEIMFGLLSPDYIRQMSVAKIVTPDTYDEDGYPIDGGLMDTRLGVIDPGLVCKTCGGRIGECPGHFGHIE
LAKPVIHIGFAKTIYKILKAVCPHCGRVAISETKRKEILEKMEKLERDGGNKWEVCEEVYKEASKVTICPHCGEIKYDIK
FEKPTTYYRIDGNEEKTLTPSDVREILEKIPDEDCILLGLNPEVARPEWMVLTVLPVPPVTVRPSITLETGERSEDDLTH
KLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGIPPAKHRSGRPLKTLAQRLKGKEGRFRYNLAGKR
VNFSSRTVISPDPCLSINEVGVPEVVAKELTVPEKVTKYNIERIRQLLRNGSEKHPGVNYVIRKMIGRDGTEQEYKVKIT
ESNKDFWAENIREGDIVERHLMDGDIVLYNRQPSLHRMSIMAHRVRVLPYRTFRHNLCVCVDGDTTVLLDGKLIKIKDLE
DKWKDVKVLTSDDLNPKLTSLSKYWKLNADEYGKKIYKIKTELGREIIATEDHPFYTTNGRKRCGELKVGDEVIIYPNDF
PMFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKLIPLTYNDQKASILARIVGHVMGDGSLIINNKNSRVVFRGD
IEDLKTIKEDLKELGYDGEEIKLHEGETEITDYNGKKRIIKGKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIK
TAPKYIKKEFLSAYFGSELTTPKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKEFGIELKVRVEEGNLRKDGYK
TKVYVASIYNHKEFFGRIGYTYANKKETLARYAYEYLLTKEKYLKDRNIKKLENNTKFITFDKFIKEKCLKNGFVKEKIV
SIEETKVDYVYDITTISETHNFIANGFLTGNCPPYNADFDGDEMNLHVPQSEEARAEAEALMLVEKHILSPRFGGPIIGA
IHDFISGAYLLTSNYFTKDEATLILRSGGIKDELWEPDKVENGVPLYSGKKIFSKALPKGLNLRYKAKICRKCDVCKKEE
CEYDAYVVIKDGELIKGVIDKNGYGAEAGLILHTIVKEFGPEAGRKFLDSATKMAIRAVMLRGFTTGIDDEDLPEEALKE
IEKVLDEAEEKVKEIIEKYERGELELLPGLNLEESREAYISNVLREARDKAGAIAERYLGLDNHAVIMAVTGARGNILNL
TQMAACLGQQSVRGKRIFRGYRGRVLPHFEKGDLGARSHGFVRSSYKKGLSPTEFFFHAMGGREGLVDQAVRTAQSGYMQ
RRLINALQDLKTEFDGTVRDSRGIMIQFKYGEDGIDPMLADRGKAVNIDRIIDKVKMKYNQ

Sequences:

>Translated_1341_residues
MERYEIPKEIGEIMFGLLSPDYIRQMSVAKIVTPDTYDEDGYPIDGGLMDTRLGVIDPGLVCKTCGGRIGECPGHFGHIE
LAKPVIHIGFAKTIYKILKAVCPHCGRVAISETKRKEILEKMEKLERDGGNKWEVCEEVYKEASKVTICPHCGEIKYDIK
FEKPTTYYRIDGNEEKTLTPSDVREILEKIPDEDCILLGLNPEVARPEWMVLTVLPVPPVTVRPSITLETGERSEDDLTH
KLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGIPPAKHRSGRPLKTLAQRLKGKEGRFRYNLAGKR
VNFSSRTVISPDPCLSINEVGVPEVVAKELTVPEKVTKYNIERIRQLLRNGSEKHPGVNYVIRKMIGRDGTEQEYKVKIT
ESNKDFWAENIREGDIVERHLMDGDIVLYNRQPSLHRMSIMAHRVRVLPYRTFRHNLCVCVDGDTTVLLDGKLIKIKDLE
DKWKDVKVLTSDDLNPKLTSLSKYWKLNADEYGKKIYKIKTELGREIIATEDHPFYTTNGRKRCGELKVGDEVIIYPNDF
PMFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKLIPLTYNDQKASILARIVGHVMGDGSLIINNKNSRVVFRGD
IEDLKTIKEDLKELGYDGEEIKLHEGETEITDYNGKKRIIKGKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIK
TAPKYIKKEFLSAYFGSELTTPKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKEFGIELKVRVEEGNLRKDGYK
TKVYVASIYNHKEFFGRIGYTYANKKETLARYAYEYLLTKEKYLKDRNIKKLENNTKFITFDKFIKEKCLKNGFVKEKIV
SIEETKVDYVYDITTISETHNFIANGFLTGNCPPYNADFDGDEMNLHVPQSEEARAEAEALMLVEKHILSPRFGGPIIGA
IHDFISGAYLLTSNYFTKDEATLILRSGGIKDELWEPDKVENGVPLYSGKKIFSKALPKGLNLRYKAKICRKCDVCKKEE
CEYDAYVVIKDGELIKGVIDKNGYGAEAGLILHTIVKEFGPEAGRKFLDSATKMAIRAVMLRGFTTGIDDEDLPEEALKE
IEKVLDEAEEKVKEIIEKYERGELELLPGLNLEESREAYISNVLREARDKAGAIAERYLGLDNHAVIMAVTGARGNILNL
TQMAACLGQQSVRGKRIFRGYRGRVLPHFEKGDLGARSHGFVRSSYKKGLSPTEFFFHAMGGREGLVDQAVRTAQSGYMQ
RRLINALQDLKTEFDGTVRDSRGIMIQFKYGEDGIDPMLADRGKAVNIDRIIDKVKMKYNQ
>Mature_1341_residues
MERYEIPKEIGEIMFGLLSPDYIRQMSVAKIVTPDTYDEDGYPIDGGLMDTRLGVIDPGLVCKTCGGRIGECPGHFGHIE
LAKPVIHIGFAKTIYKILKAVCPHCGRVAISETKRKEILEKMEKLERDGGNKWEVCEEVYKEASKVTICPHCGEIKYDIK
FEKPTTYYRIDGNEEKTLTPSDVREILEKIPDEDCILLGLNPEVARPEWMVLTVLPVPPVTVRPSITLETGERSEDDLTH
KLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGIPPAKHRSGRPLKTLAQRLKGKEGRFRYNLAGKR
VNFSSRTVISPDPCLSINEVGVPEVVAKELTVPEKVTKYNIERIRQLLRNGSEKHPGVNYVIRKMIGRDGTEQEYKVKIT
ESNKDFWAENIREGDIVERHLMDGDIVLYNRQPSLHRMSIMAHRVRVLPYRTFRHNLCVCVDGDTTVLLDGKLIKIKDLE
DKWKDVKVLTSDDLNPKLTSLSKYWKLNADEYGKKIYKIKTELGREIIATEDHPFYTTNGRKRCGELKVGDEVIIYPNDF
PMFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKLIPLTYNDQKASILARIVGHVMGDGSLIINNKNSRVVFRGD
IEDLKTIKEDLKELGYDGEEIKLHEGETEITDYNGKKRIIKGKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIK
TAPKYIKKEFLSAYFGSELTTPKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKEFGIELKVRVEEGNLRKDGYK
TKVYVASIYNHKEFFGRIGYTYANKKETLARYAYEYLLTKEKYLKDRNIKKLENNTKFITFDKFIKEKCLKNGFVKEKIV
SIEETKVDYVYDITTISETHNFIANGFLTGNCPPYNADFDGDEMNLHVPQSEEARAEAEALMLVEKHILSPRFGGPIIGA
IHDFISGAYLLTSNYFTKDEATLILRSGGIKDELWEPDKVENGVPLYSGKKIFSKALPKGLNLRYKAKICRKCDVCKKEE
CEYDAYVVIKDGELIKGVIDKNGYGAEAGLILHTIVKEFGPEAGRKFLDSATKMAIRAVMLRGFTTGIDDEDLPEEALKE
IEKVLDEAEEKVKEIIEKYERGELELLPGLNLEESREAYISNVLREARDKAGAIAERYLGLDNHAVIMAVTGARGNILNL
TQMAACLGQQSVRGKRIFRGYRGRVLPHFEKGDLGARSHGFVRSSYKKGLSPTEFFFHAMGGREGLVDQAVRTAQSGYMQ
RRLINALQDLKTEFDGTVRDSRGIMIQFKYGEDGIDPMLADRGKAVNIDRIIDKVKMKYNQ

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DOD-type homing endonuclease domain

Homologues:

Organism=Homo sapiens, GI4505939, Length=500, Percent_Identity=43.6, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI39725938, Length=508, Percent_Identity=37.992125984252, Blast_Score=342, Evalue=1e-93,
Organism=Homo sapiens, GI103471997, Length=453, Percent_Identity=34.4370860927152, Blast_Score=225, Evalue=2e-58,
Organism=Escherichia coli, GI2367335, Length=499, Percent_Identity=27.2545090180361, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71987878, Length=482, Percent_Identity=40.8713692946058, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25145495, Length=438, Percent_Identity=39.9543378995434, Blast_Score=321, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI71998295, Length=466, Percent_Identity=30.9012875536481, Blast_Score=197, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320061, Length=475, Percent_Identity=44.8421052631579, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6324690, Length=436, Percent_Identity=40.3669724770642, Blast_Score=326, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6324917, Length=445, Percent_Identity=33.2584269662921, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI17530899, Length=477, Percent_Identity=43.6058700209644, Blast_Score=385, Evalue=1e-106,
Organism=Drosophila melanogaster, GI281360912, Length=502, Percent_Identity=38.8446215139442, Blast_Score=343, Evalue=4e-94,
Organism=Drosophila melanogaster, GI17647875, Length=451, Percent_Identity=33.2594235033259, Blast_Score=214, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOA1_METJA (Q58445)

Other databases:

- EMBL:   L77117
- RefSeq:   NP_248036.1
- ProteinModelPortal:   Q58445
- GeneID:   1451939
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1042
- NMPDR:   fig|243232.1.peg.1073
- TIGR:   MJ1042
- HOGENOM:   HBG499785
- OMA:   HKLVDII
- ProtClustDB:   CLSK2567402
- BioCyc:   MJAN243232:MJ_1042-MONOMER
- BRENDA:   2.7.7.6
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012758
- PRINTS:   PR00379
- SMART:   SM00305
- SMART:   SM00306
- SMART:   SM00663
- TIGRFAMs:   TIGR01443
- TIGRFAMs:   TIGR01445
- TIGRFAMs:   TIGR02390

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 152783; Mature: 152783

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50818 INTEIN_C_TER; PS50819 INTEIN_ENDONUCLEASE; PS50817 INTEIN_N_TER; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERYEIPKEIGEIMFGLLSPDYIRQMSVAKIVTPDTYDEDGYPIDGGLMDTRLGVIDPGL
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHCCCCCCCCCC
VCKTCGGRIGECPGHFGHIELAKPVIHIGFAKTIYKILKAVCPHCGRVAISETKRKEILE
HHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KMEKLERDGGNKWEVCEEVYKEASKVTICPHCGEIKYDIKFEKPTTYYRIDGNEEKTLTP
HHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCH
SDVREILEKIPDEDCILLGLNPEVARPEWMVLTVLPVPPVTVRPSITLETGERSEDDLTH
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEECCEEEEECCCCCHHHHHH
KLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGIPPAKHRSGRPLKT
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LAQRLKGKEGRFRYNLAGKRVNFSSRTVISPDPCLSINEVGVPEVVAKELTVPEKVTKYN
HHHHHCCCCCCEEEEECCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
IERIRQLLRNGSEKHPGVNYVIRKMIGRDGTEQEYKVKITESNKDFWAENIREGDIVERH
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCHHHHH
LMDGDIVLYNRQPSLHRMSIMAHRVRVLPYRTFRHNLCVCVDGDTTVLLDGKLIKIKDLE
HCCCCEEEECCCCCHHHHHHHHHHHHHCEEHHHCCCEEEEECCCEEEEECCEEEEEECCC
DKWKDVKVLTSDDLNPKLTSLSKYWKLNADEYGKKIYKIKTELGREIIATEDHPFYTTNG
CCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCCCEEECCC
RKRCGELKVGDEVIIYPNDFPMFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKL
HHHCCCEECCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCEE
IPLTYNDQKASILARIVGHVMGDGSLIINNKNSRVVFRGDIEDLKTIKEDLKELGYDGEE
EEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCE
IKLHEGETEITDYNGKKRIIKGKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIK
EEEECCCCEEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCEECCCCHHHH
TAPKYIKKEFLSAYFGSELTTPKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKE
HHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGIELKVRVEEGNLRKDGYKTKVYVASIYNHKEFFGRIGYTYANKKETLARYAYEYLLTK
CCCEEEEEEECCCCCCCCCEEEEEEEEHHCCHHHHHHCCCEECCHHHHHHHHHHHHHHHH
EKYLKDRNIKKLENNTKFITFDKFIKEKCLKNGFVKEKIVSIEETKVDYVYDITTISETH
HHHHHCCCHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEHHHHH
NFIANGFLTGNCPPYNADFDGDEMNLHVPQSEEARAEAEALMLVEKHILSPRFGGPIIGA
HHHHCCEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IHDFISGAYLLTSNYFTKDEATLILRSGGIKDELWEPDKVENGVPLYSGKKIFSKALPKG
HHHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
LNLRYKAKICRKCDVCKKEECEYDAYVVIKDGELIKGVIDKNGYGAEAGLILHTIVKEFG
CCEEHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEHHHCCCCCCCHHHHHHHHHHHHHC
PEAGRKFLDSATKMAIRAVMLRGFTTGIDDEDLPEEALKEIEKVLDEAEEKVKEIIEKYE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RGELELLPGLNLEESREAYISNVLREARDKAGAIAERYLGLDNHAVIMAVTGARGNILNL
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHH
TQMAACLGQQSVRGKRIFRGYRGRVLPHFEKGDLGARSHGFVRSSYKKGLSPTEFFFHAM
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHC
GGREGLVDQAVRTAQSGYMQRRLINALQDLKTEFDGTVRDSRGIMIQFKYGEDGIDPMLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCHHH
DRGKAVNIDRIIDKVKMKYNQ
CCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MERYEIPKEIGEIMFGLLSPDYIRQMSVAKIVTPDTYDEDGYPIDGGLMDTRLGVIDPGL
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHCCCCCCCCCC
VCKTCGGRIGECPGHFGHIELAKPVIHIGFAKTIYKILKAVCPHCGRVAISETKRKEILE
HHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KMEKLERDGGNKWEVCEEVYKEASKVTICPHCGEIKYDIKFEKPTTYYRIDGNEEKTLTP
HHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCH
SDVREILEKIPDEDCILLGLNPEVARPEWMVLTVLPVPPVTVRPSITLETGERSEDDLTH
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEECCEEEEECCCCCHHHHHH
KLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGIPPAKHRSGRPLKT
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LAQRLKGKEGRFRYNLAGKRVNFSSRTVISPDPCLSINEVGVPEVVAKELTVPEKVTKYN
HHHHHCCCCCCEEEEECCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
IERIRQLLRNGSEKHPGVNYVIRKMIGRDGTEQEYKVKITESNKDFWAENIREGDIVERH
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCHHHHH
LMDGDIVLYNRQPSLHRMSIMAHRVRVLPYRTFRHNLCVCVDGDTTVLLDGKLIKIKDLE
HCCCCEEEECCCCCHHHHHHHHHHHHHCEEHHHCCCEEEEECCCEEEEECCEEEEEECCC
DKWKDVKVLTSDDLNPKLTSLSKYWKLNADEYGKKIYKIKTELGREIIATEDHPFYTTNG
CCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCCCEEECCC
RKRCGELKVGDEVIIYPNDFPMFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKL
HHHCCCEECCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCEE
IPLTYNDQKASILARIVGHVMGDGSLIINNKNSRVVFRGDIEDLKTIKEDLKELGYDGEE
EEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCE
IKLHEGETEITDYNGKKRIIKGKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIK
EEEECCCCEEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCEECCCCHHHH
TAPKYIKKEFLSAYFGSELTTPKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKE
HHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGIELKVRVEEGNLRKDGYKTKVYVASIYNHKEFFGRIGYTYANKKETLARYAYEYLLTK
CCCEEEEEEECCCCCCCCCEEEEEEEEHHCCHHHHHHCCCEECCHHHHHHHHHHHHHHHH
EKYLKDRNIKKLENNTKFITFDKFIKEKCLKNGFVKEKIVSIEETKVDYVYDITTISETH
HHHHHCCCHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEHHHHH
NFIANGFLTGNCPPYNADFDGDEMNLHVPQSEEARAEAEALMLVEKHILSPRFGGPIIGA
HHHHCCEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IHDFISGAYLLTSNYFTKDEATLILRSGGIKDELWEPDKVENGVPLYSGKKIFSKALPKG
HHHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
LNLRYKAKICRKCDVCKKEECEYDAYVVIKDGELIKGVIDKNGYGAEAGLILHTIVKEFG
CCEEHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEHHHCCCCCCCHHHHHHHHHHHHHC
PEAGRKFLDSATKMAIRAVMLRGFTTGIDDEDLPEEALKEIEKVLDEAEEKVKEIIEKYE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RGELELLPGLNLEESREAYISNVLREARDKAGAIAERYLGLDNHAVIMAVTGARGNILNL
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHH
TQMAACLGQQSVRGKRIFRGYRGRVLPHFEKGDLGARSHGFVRSSYKKGLSPTEFFFHAM
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHC
GGREGLVDQAVRTAQSGYMQRRLINALQDLKTEFDGTVRDSRGIMIQFKYGEDGIDPMLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCHHH
DRGKAVNIDRIIDKVKMKYNQ
CCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087