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The map label for this gene is mtd

Identifier: 15669224

GI number: 15669224

Start: 966335

End: 967168

Strand: Reverse

Name: mtd

Synonym: MJ1035

Alternate gene names: 15669224

Gene position: 967168-966335 (Counterclockwise)

Preceding gene: 15669240

Following gene: 161579523

Centisome position: 58.09

GC content: 39.33

Gene sequence:

>834_bases
TTGGTCGTAAAAATAGGAATAATAAAGTGTGGTAACATAGGAATGTCCCCAGTTGTTGATTTAGCATTAGATGAGAGAGC
AGATAGAAAGGATATAGCAGTTAGAGTCTTAGGTAGTGGGGCAAAGATGGACCCAGAATCAGTTGAAGAGGTAACAAAGA
AGATGGTTGAGGAAGTTAAGCCAGACTTCATCATCTACATAGGTCCAAATCCAGCCGCTCCAGGGCCTAAGAAGGCAAGA
GAAATTTTAAGTCAAAGTGGAATTCCTGCAGTGATTATTGGAGACGCTCCAGGATTAAGAGTTAAGGATGAGATGGAACA
GCAAGGTTTAGGATACATAATTATAAAATGTGACCCAATGATTGGTGCAAGAAGGGAGTTTTTAGACCCTGTTGAAATGG
CATTATTCAATGCAGATGTTATAAGGGTTTTAGCTGGAACTGGAGCTTTAAGAATCGTTCAAGAGGCAATTGATAAGATG
ATTGACGCAGTTAAAGAGGGCAAAGAAATAGAATTACCAAAGATTGTTATTACAGAACAGAAGGCAGTTGAAGCTATGGA
ATTCACAAACCCTTACGCAAAGGCAAAGGCCATGGCTGCATTTACAATTGCTGAGAAGGTTGGAGATGTTGATGTTAAAG
GTTGTTTCATGACAAAAGAGGCAGAGAAATATATCCCAATCGTTGCCTCTGCTCATGAAATGATTAGATATGCCGCTAAG
TTGGTAGATGAAGCAAGAGAGTTAGAAAAAGCAATGGATGCTGTTAGTAGAAAACCACATCACCCAGAAGGAAAGAGATT
GAGCAAAAAAGCATTAATGGAGAAACCAGAATAA

Upstream 100 bases:

>100_bases
ATTATATATCAGGTGAATATTCCAAATAAGTAGTAAGATATTTATTGGATAAGCTTGGATAATACTAATATCCCTATTAA
GTAATAAAAAAGGTGATAAC

Downstream 100 bases:

>100_bases
ATTAATCCTTTTTAATTCTATTTTAATTTTTTCCTTTTATTATTTTGCAAATCTCTTTTAGTAACTGCAGTTTATTTCCT
TTATAATCAACCTCTACACA

Product: F420-dependent methylenetetrahydromethanopterin dehydrogenase

Products: NA

Alternate protein names: MTD; Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVKPDFIIYIGPNPAAPGPKKAR
EILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPMIGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKM
IDAVKEGKEIELPKIVITEQKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE

Sequences:

>Translated_277_residues
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVKPDFIIYIGPNPAAPGPKKAR
EILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPMIGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKM
IDAVKEGKEIELPKIVITEQKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE
>Mature_277_residues
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVKPDFIIYIGPNPAAPGPKKAR
EILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPMIGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKM
IDAVKEGKEIELPKIVITEQKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE

Specific function: Catalyzes the reversible reduction of methenyl- H(4)MPT(+) to methylene-H(4)MPT

COG id: COG1927

COG function: function code C; Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTD_METJA (Q58441)

Other databases:

- EMBL:   L77117
- PIR:   B64429
- RefSeq:   NP_248029.1
- ProteinModelPortal:   Q58441
- SMR:   Q58441
- GeneID:   1451932
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1035
- NMPDR:   fig|243232.1.peg.1066
- TIGR:   MJ1035
- HOGENOM:   HBG538567
- OMA:   IVASAHE
- ProtClustDB:   PRK00994
- BioCyc:   MJAN243232:MJ_1035-MONOMER
- BRENDA:   1.5.99.9
- GO:   GO:0015948
- HAMAP:   MF_00058
- InterPro:   IPR002844
- PIRSF:   PIRSF005627
- ProDom:   PD017604

Pfam domain/function: PF01993 MTD; SSF102324 MeTD

EC number: =1.5.99.9

Molecular weight: Translated: 30306; Mature: 30306

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
CEEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PDFIIYIGPNPAAPGPKKAREILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
CCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEECCC
IGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKMIDAVKEGKEIELPKIVITEQ
CCCHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECH
KAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHH
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
CEEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PDFIIYIGPNPAAPGPKKAREILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
CCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEECCC
IGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKMIDAVKEGKEIELPKIVITEQ
CCCHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECH
KAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHH
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087