Click here to switch to the map view.

The map label for this gene is corA

Identifier: 15669222

GI number: 15669222

Start: 965086

End: 966039

Strand: Direct

Name: corA

Synonym: MJ1033

Alternate gene names: 15669222

Gene position: 965086-966039 (Clockwise)

Preceding gene: 15669221

Following gene: 15669223

Centisome position: 57.96

GC content: 31.03

Gene sequence:

>954_bases
ATGATTACGGTAATTGCTATAGCTAAAGATGGCAGTATTGTCGAGCCAAAACTTGATGAAATTAGCTTTGAAGATTATAG
ACTTATTTGGATTGATTGTTATGACCCAAAAGATGAAGAGCTATATAAACTCTCTAAAAAAATTGGTATTTCTGTCTCTG
ATTTACAAATTGGTTTAGATGAGCAGGAAATTCCAAGGGTAGAGGAAGATGAGGACTTTTACTTAATTATTTACAAAGCT
CCATTATTTGAAGAGGATATTACAACAACATCCTTAGGTATCTATATTAAGAATAACCTCCTACTAACAATCCACTCGGA
TAAAATAAAGGCTATTGGAAGATTGCATAAATTAATATCAACAAAAAAACCAAGAATTGTATTTGAAAGAGGAATTGGCT
TTTTATTATACCATATATTAAATGAGATTACAAGGAGTTATTCAAGAATTTTAATGAATTTAGAAGATGAGTTGGAGGAG
TTGGAGGATAAATTATTAGCTGGCTATGACAGAGAGGTTATGGAAAAAATTTTAGGATTAAGAAAAACTTTGGTTTATTT
TCATAAATCTTTAATAGCTAATAGGGATGTCTTAGTTTTATTAAAGAGAAAGTATCTTCCAATAACCACAAAAGAAGACA
GAGAGAACTTTGAAGACCTTTACTACGACACTTTACAGTTAATTGATATGTCAGCAACCTATAGAGAGGTTTTAACCTCA
ATGATGGATATAACCCTCTCATTAGAAAATATAAAGATGAACCAAATTATGAAAATCCTAACTATGGTTACGACAATTTT
CGCTGTTCCCATGTGGATTACTGGAATATACGGGATGAACTTCTCTTATTTACCTTTAGCAAACAACCCTCAAGGTTTTT
GGCTTGTAATGGCTTTGATGGTTGTAATAATTATGATATTTGTCTATATATTTAGAAGGTCAGGATGGATTTAG

Upstream 100 bases:

>100_bases
TACATATCTATTGTTATTATTCTTTCAGTTATCCTATTTACAAAAAGTTCAAAAGAAGATAAATTCAAAAAATTAAAAAA
TAGCATCACAAAGGGCTAAT

Downstream 100 bases:

>100_bases
AGGGAGAAAATGATTATATGGCCATCTTATATAGATAAAAAGAAAAGTAGGAGAGAAGGAAGAAAAGTTCCAGAAGAGTT
AGCTATAGAAAAGCCATCTT

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MITVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISVSDLQIGLDEQEIPRVEEDEDFYLIIYKA
PLFEEDITTTSLGIYIKNNLLLTIHSDKIKAIGRLHKLISTKKPRIVFERGIGFLLYHILNEITRSYSRILMNLEDELEE
LEDKLLAGYDREVMEKILGLRKTLVYFHKSLIANRDVLVLLKRKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTS
MMDITLSLENIKMNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALMVVIIMIFVYIFRRSGWI

Sequences:

>Translated_317_residues
MITVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISVSDLQIGLDEQEIPRVEEDEDFYLIIYKA
PLFEEDITTTSLGIYIKNNLLLTIHSDKIKAIGRLHKLISTKKPRIVFERGIGFLLYHILNEITRSYSRILMNLEDELEE
LEDKLLAGYDREVMEKILGLRKTLVYFHKSLIANRDVLVLLKRKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTS
MMDITLSLENIKMNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALMVVIIMIFVYIFRRSGWI
>Mature_317_residues
MITVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISVSDLQIGLDEQEIPRVEEDEDFYLIIYKA
PLFEEDITTTSLGIYIKNNLLLTIHSDKIKAIGRLHKLISTKKPRIVFERGIGFLLYHILNEITRSYSRILMNLEDELEE
LEDKLLAGYDREVMEKILGLRKTLVYFHKSLIANRDVLVLLKRKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTS
MMDITLSLENIKMNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALMVVIIMIFVYIFRRSGWI

Specific function: Mediates influx of magnesium ions

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Homologues:

Organism=Escherichia coli, GI2367297, Length=298, Percent_Identity=20.8053691275168, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORA_METJA (Q58439)

Other databases:

- EMBL:   L77117
- PIR:   H64428
- RefSeq:   NP_248027.1
- ProteinModelPortal:   Q58439
- SMR:   Q58439
- GeneID:   1451930
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1033
- NMPDR:   fig|243232.1.peg.1064
- TIGR:   MJ1033
- HOGENOM:   HBG541091
- OMA:   LMELHED
- ProtClustDB:   CLSK876434
- BioCyc:   MJAN243232:MJ_1033-MONOMER
- InterPro:   IPR004488
- InterPro:   IPR002523
- PANTHER:   PTHR21535:SF1
- TIGRFAMs:   TIGR00383

Pfam domain/function: PF01544 CorA

EC number: NA

Molecular weight: Translated: 37142; Mature: 37142

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xca9f0b0)-; HASH(0xdf52124)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISVSDLQIGLD
CEEEEEEECCCCCCCCCHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEHEEECCC
EQEIPRVEEDEDFYLIIYKAPLFEEDITTTSLGIYIKNNLLLTIHSDKIKAIGRLHKLIS
HHHCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCEEEEEECHHHHHHHHHHHHHC
TKKPRIVFERGIGFLLYHILNEITRSYSRILMNLEDELEELEDKLLAGYDREVMEKILGL
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RKTLVYFHKSLIANRDVLVLLKRKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTS
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MMDITLSLENIKMNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
VVIIMIFVYIFRRSGWI
HHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MITVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISVSDLQIGLD
CEEEEEEECCCCCCCCCHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEHEEECCC
EQEIPRVEEDEDFYLIIYKAPLFEEDITTTSLGIYIKNNLLLTIHSDKIKAIGRLHKLIS
HHHCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCEEEEEECHHHHHHHHHHHHHC
TKKPRIVFERGIGFLLYHILNEITRSYSRILMNLEDELEELEDKLLAGYDREVMEKILGL
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RKTLVYFHKSLIANRDVLVLLKRKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTS
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MMDITLSLENIKMNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
VVIIMIFVYIFRRSGWI
HHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087