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The map label for this gene is ileS

Identifier: 15669137

GI number: 15669137

Start: 877540

End: 880659

Strand: Reverse

Name: ileS

Synonym: MJ0947

Alternate gene names: 15669137

Gene position: 880659-877540 (Counterclockwise)

Preceding gene: 15669138

Following gene: 15669136

Centisome position: 52.89

GC content: 33.69

Gene sequence:

>3120_bases
ATGAAAAAAGTAGAGCCTGTTAATTTTAGAGAGTTGGATAAGAAGATAAAAAAGTTCTGGGAAGAGAATGACATATATCA
AAAAGTAAAGAAAAAGAATGAAAGAAATAAGGAATTTTATTTTGTTGATGGTCCTCCATACTGTTCTGGAGCTATACACT
TAGGGACTGCATGGAATAAGATAATTAAAGACACTTATCTAAGATTTAAGAGAATGCAAGGTTATAATGTTTTGGATAAA
GCTGGATGGGACATGCATGGATTGCCAATAGAAGTTAAAGTTGAAAATGAATTTGGAATAAAGAACAAGAAAGAGATAGA
AACAAAAATTGGAGTAAAGCAATTTATAGAAAAGTGTAAAGAATTCGCTTTAAAACATAAGGAAATTATGGAAAAGCAAT
TTAAAAACTTAGGAGTTTGGTTAGATTGGGAAAACGCCTATATGCCAATAACTAAGGAATATATGGAAATTGGATGGTGG
ACATTAAAGGTTGCTCATGAGAAGGGATTATTAACAAGAGATTTAAGGGTTGTCTATTGGTGTCCAAGATGTGAAACTGC
CTTAGCGGAGCATGAGGTTAGAGGAGAGTATAAGGAAGTTTATGACCCATCCGTTTATGTAAAATTCAGATTAGCAAATG
AAGAAAACACATACATTGTTATTTGGACAACAACACCATGGACTTTAGTTGCTAACTTGGCTGTTACTGTCCATCCAGAT
TATGACTATGCATATGTAGAAGTTGAATTTGATGACAAAAAAGAGGTTTGGATTATTGCTGAAAAGTTAGTTGAGGAAGT
TATAAACAAAGCTAAAAAATTCCATAACATCAAAAACTACAAAATAATCAAAAAAGTTAAAGGAAAAGAATTGGAAGGTA
TAAAATATATTCATCCATTATTAGAAGAGAATGAGAGACAGAAAGAATTTGCAGAATTAGAAAATGCTCATACAGTTATT
TTAGGAGAGCATGTAACCTTAGAGGGAGGAACTGGGTTGGTTCATACTGCCCCAGGACACGGGGAAGAGGACTTTGAAGT
TGGTAAAAAATACAATTTGCCAATCTATTCACCAATAGACGATGAAGGTAAATATGTAGAAGGAAAATGGAAGGGCGTTT
TTGTTAAAGATGCGGATGCTGAAATAATTGAAACCCTAAAAAACAAAGGATTGTTAGTTTATGCTGGAAAGATAAAACAC
AGCTATCCACACTGTTGGAGATGTAAAACTCCTCTATTATTTAGAGCTACAGAGCAGTGGTTCTTAGAGATATCAAAGAT
TAAAGATAACATTATAGAGCATGCTAAAACAGTTCAGTGGATACCACACTGGGTTGAAACAAGATATATAAATGGAGTTA
AGTTCGTTGGAGACTGGAATATAAGTAGGCAGAGATACTGGGGAATCCCTATTCCAGTATGGGTGTGTGAGAAGTGTGGA
AAATACATTGTTGTAGGAAGTGTTGAAGAATTAGAAGAGAAGATGATAAATAAAGATGAAGTTGGAGAGATTAATGATTT
ACACAAACCAACAGTTGATAAAATAAAGCTGAGATGTGAATGTGGAGGAGAAATGAAAAGAGTTCCAGATGTCTTAGATG
TTTGGTTTGACTCTGGTTTAGCTCCTTATGCTTCAATTGGAGTAAAAGAGCTTAAAAAAGCAGACTTTATAACAGAGGGA
CATGACCAAGTTACTAAATGGTTTTATTCACAGCATGCACTCTCAGCAATAGTATTTAACGATATTCCATACAAAAAGTG
TTTAATGCATGGCTTCACTTTAGATGAGCATGGAGACAAGATGAGTAAGAGTTTGGGTAATGTAGTTAATCCAGATGATG
TCGTTGAAAAGTATGGGGCTGATTTATTAAGGTTTTATTTATTGAGTGCAAATAAGGTTTGGGAAGATTTAAGGTTTGTA
TGGAGTGAGATGGATGATGTTTTAAGCTTATTCAACACTTTATGGAACGCCTATATGTTTGCTGTAAATTACATGGTGTT
AGATAACTTTAAACCAGATGAAAAATACTTTGAATATTTAAAAGATGAGGATAGATGGATTGTAAGCAGAATAAACAGTG
TTGCTAAGATAGCAATTGAAAATCTTGAAGTCCCATACTTCCACACATACACTTGGACATTAAAGGATTTCATATTAAAT
GACTTAAGTAGATGGTATATTAGGTTGATTAGAGACAGAACATGGAAAGAGAAGGATGACGCTGATAAATTAGCAGCATA
TCAAACACTCTACTATGTCTTATTAAAGTTAGCTACAATATTGGCTCCAGTAGCTCCACATACTGCTGAGGCAATATATC
AAAACCTAAAAACAGAAGATATGGAAGAAAGTATCTTCATGAATAAAATAGAGGTTGATGAAGAGTTTATTGATGAGGAG
TTAGAGAGAGATATGGCAATAGTTAGAGATGTCGTTGATGCAATCTACAGAGGAAGGGATAGGATAAAATACACCTTAAG
ATACCCATTGAAAGAAATAACTATTGCTGGTGGAGAAGAGGTTAAAAAAGCTGTAGAGAGATTTGAATACATAATAAAAG
AGCAAGGTAATGTTAAAAATATCAAATTTGGAGAGGTTGAAGGTAGCAAGTATATAATAAAGCCAAACTACAGAGAGTTA
GGTAAGAGATATAGAAGTGAGGTTCCAAAGGTTGTTGAGGCATTAAATAAAGCAGATGCTAAGGAGTTGATGGAGAGGTT
GAAAGAAGGAGCTGTAATATTAGATGGATATGAGATTAAGCCAGAATATGTTGAAATTAGATTGGAAATTCCTGAACATA
TAGCAGGAGTTGAATTCTCAAAGGGAACTGTCTTTATAAATACCGAGATTACTGATGATTTGATAAAAGAGGGGCTAATG
AGAGAGGTTATAAGAAGAATCCAAGCTATGAGGAAGGATATGGATTTAGATATTGAGGAGAAGATTAAAATTAAAGTTGA
GGGCATTGACTTAGATGAATTTAAGGAGATTATTGAGAGGGAAGTTAGAGGTCAGTTTGTTGATGAGATAAAGGCAGATT
ACGAAAAAGATTGGGAGATAAAAACACCAAATGGAGAGAAATACAACGTTAAAATTGCTATTGAGAGAATAAATAAATAA

Upstream 100 bases:

>100_bases
TATTTGAGTAAGATAATTTCAAGAATTAGTCGATTAAAAGAATTTAAAAGCAATTTGGATGAGATAGTTTCAGATATAAT
CTCAAACATGAGGTGAGTGG

Downstream 100 bases:

>100_bases
AAATTTCTTTTTAGTTTTCTTTAATACTTTTACTTTTATTTCTATTTTTAATTGTTTTTAATTTATAAAACTAAGACAAT
ATTATTCTGTGTGATAATAT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1039; Mature: 1039

Protein sequence:

>1039_residues
MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNKIIKDTYLRFKRMQGYNVLDK
AGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCKEFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWW
TLKVAHEKGLLTRDLRVVYWCPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD
YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPLLEENERQKEFAELENAHTVI
LGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPIDDEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKH
SYPHCWRCKTPLLFRATEQWFLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCG
KYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGLAPYASIGVKELKKADFITEG
HDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFV
WSEMDDVLSLFNTLWNAYMFAVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILN
DLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTEDMEESIFMNKIEVDEEFIDEE
LERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEEVKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYREL
GKRYRSEVPKVVEALNKADAKELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLM
REVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEIKTPNGEKYNVKIAIERINK

Sequences:

>Translated_1039_residues
MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNKIIKDTYLRFKRMQGYNVLDK
AGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCKEFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWW
TLKVAHEKGLLTRDLRVVYWCPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD
YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPLLEENERQKEFAELENAHTVI
LGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPIDDEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKH
SYPHCWRCKTPLLFRATEQWFLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCG
KYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGLAPYASIGVKELKKADFITEG
HDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFV
WSEMDDVLSLFNTLWNAYMFAVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILN
DLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTEDMEESIFMNKIEVDEEFIDEE
LERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEEVKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYREL
GKRYRSEVPKVVEALNKADAKELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLM
REVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEIKTPNGEKYNVKIAIERINK
>Mature_1039_residues
MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNKIIKDTYLRFKRMQGYNVLDK
AGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCKEFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWW
TLKVAHEKGLLTRDLRVVYWCPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD
YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPLLEENERQKEFAELENAHTVI
LGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPIDDEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKH
SYPHCWRCKTPLLFRATEQWFLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCG
KYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGLAPYASIGVKELKKADFITEG
HDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFV
WSEMDDVLSLFNTLWNAYMFAVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILN
DLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTEDMEESIFMNKIEVDEEFIDEE
LERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEEVKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYREL
GKRYRSEVPKVVEALNKADAKELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLM
REVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEIKTPNGEKYNVKIAIERINK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1047, Percent_Identity=33.1423113658071, Blast_Score=551, Evalue=1e-156,
Organism=Homo sapiens, GI94721241, Length=1047, Percent_Identity=33.1423113658071, Blast_Score=551, Evalue=1e-156,
Organism=Homo sapiens, GI46852147, Length=784, Percent_Identity=32.015306122449, Blast_Score=354, Evalue=2e-97,
Organism=Homo sapiens, GI5454158, Length=845, Percent_Identity=23.4319526627219, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI268370293, Length=884, Percent_Identity=22.8506787330317, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI268370297, Length=884, Percent_Identity=22.8506787330317, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI268370295, Length=867, Percent_Identity=22.8373702422145, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI7661872, Length=182, Percent_Identity=25.8241758241758, Blast_Score=68, Evalue=5e-11,
Organism=Escherichia coli, GI2367096, Length=788, Percent_Identity=34.010152284264, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1790708, Length=852, Percent_Identity=24.2957746478873, Blast_Score=209, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17541896, Length=1012, Percent_Identity=33.7944664031621, Blast_Score=514, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI71980946, Length=802, Percent_Identity=30.4239401496259, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI72001587, Length=875, Percent_Identity=24.2285714285714, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17510661, Length=838, Percent_Identity=23.7470167064439, Blast_Score=191, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1040, Percent_Identity=33.1730769230769, Blast_Score=521, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6325217, Length=861, Percent_Identity=29.3844367015099, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6321531, Length=819, Percent_Identity=23.8095238095238, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6323414, Length=561, Percent_Identity=21.0338680926916, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574730, Length=1020, Percent_Identity=30.7843137254902, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24668547, Length=1020, Percent_Identity=30.7843137254902, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24668543, Length=1020, Percent_Identity=30.7843137254902, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI281366294, Length=779, Percent_Identity=30.6803594351733, Blast_Score=336, Evalue=5e-92,
Organism=Drosophila melanogaster, GI17864482, Length=851, Percent_Identity=23.6192714453584, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24653289, Length=851, Percent_Identity=23.6192714453584, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21355675, Length=831, Percent_Identity=23.826714801444, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21355409, Length=183, Percent_Identity=27.8688524590164, Blast_Score=73, Evalue=9e-13,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_METJA (Q58357)

Other databases:

- EMBL:   L77117
- PIR:   C64418
- RefSeq:   NP_247942.1
- ProteinModelPortal:   Q58357
- SMR:   Q58357
- GeneID:   1451844
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0947
- NMPDR:   fig|243232.1.peg.979
- TIGR:   MJ0947
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   MJAN243232:MJ_0947-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 122235; Mature: 122235

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 603-603

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNK
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECHHHHH
IIKDTYLRFKRMQGYNVLDKAGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCK
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWWTLKVAHEKGLLTRDLRVVYW
HHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHCCEEEEEEECCCCCEEECCEEEEE
CPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD
CCCHHHHHHHHHHCCCHHHHCCCEEEEEEEEECCCCCEEEEEECCCHHEEEEEEEEEECC
YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPL
CCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH
LEENERQKEFAELENAHTVILGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPID
HCCCHHHHHHHHHCCCCEEEEECEEEEECCCCEEECCCCCCCCHHHCCCEECCCCCCCCC
DEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKHSYPHCWRCKTPLLFRATEQW
CCCCEEECEEEEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEECHHH
FLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEECCCCCCCEECCCCCHHHHHHHCC
KYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGL
CEEEECCHHHHHHHHCCCCCCCCCHHCCCCCHHHEEEEECCCCCHHHCHHHHHHHHCCCC
APYASIGVKELKKADFITEGHDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDK
CHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHH
MSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFVWSEMDDVLSLFNTLWNAYMF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILN
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
DLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTED
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
MEESIFMNKIEVDEEFIDEELERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEECCCHH
VKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYRELGKRYRSEVPKVVEALNKADA
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCH
KELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLM
HHHHHHHHCCCEEEECEECCCCEEEEEEECCHHHCCCEECCCEEEEECCCCHHHHHHHHH
REVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEI
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
KTPNGEKYNVKIAIERINK
ECCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNK
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECHHHHH
IIKDTYLRFKRMQGYNVLDKAGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCK
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWWTLKVAHEKGLLTRDLRVVYW
HHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHCCEEEEEEECCCCCEEECCEEEEE
CPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD
CCCHHHHHHHHHHCCCHHHHCCCEEEEEEEEECCCCCEEEEEECCCHHEEEEEEEEEECC
YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPL
CCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH
LEENERQKEFAELENAHTVILGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPID
HCCCHHHHHHHHHCCCCEEEEECEEEEECCCCEEECCCCCCCCHHHCCCEECCCCCCCCC
DEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKHSYPHCWRCKTPLLFRATEQW
CCCCEEECEEEEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEECHHH
FLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEECCCCCCCEECCCCCHHHHHHHCC
KYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGL
CEEEECCHHHHHHHHCCCCCCCCCHHCCCCCHHHEEEEECCCCCHHHCHHHHHHHHCCCC
APYASIGVKELKKADFITEGHDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDK
CHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHH
MSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFVWSEMDDVLSLFNTLWNAYMF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILN
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
DLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTED
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
MEESIFMNKIEVDEEFIDEELERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEECCCHH
VKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYRELGKRYRSEVPKVVEALNKADA
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCH
KELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLM
HHHHHHHHCCCEEEECEECCCCEEEEEEECCHHHCCCEECCCEEEEECCCCHHHHHHHHH
REVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEI
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
KTPNGEKYNVKIAIERINK
ECCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087